Pasty injectable biodegradable polymers derived from natural acids

Journal of Biomedical Materials Research - Part A

Volumn 83, Issue 4, 2007, Pages 1138-1145

  Krasko, Michal Y ^a,b   Domb, Abraham J ^a,b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Controlled release; Fatty acids; Gelling polymers; Poly(ester anhydride)s; Ricinoleic acid

Indexed keywords

CHROMATOGRAPHY; DRUG DELIVERY; DRUG PRODUCTS; OLEIC ACID; POLYESTERS; SYNTHESIS (CHEMICAL); TISSUE;

ALKANEDICARBOXYLIC ACIDS; GELLING POLYMERS; RICINOLEIC ACIDS;

BIODEGRADABLE POLYMERS;

ACID ANHYDRIDE; CARBENE; CARBOXYLIC ACID; OLIGOMER; POLYMER; RICINOLEIC ACID;

ARTICLE; BIODEGRADABLE IMPLANT; CHROMATOGRAPHY; MELTING POINT; POLYMERIZATION; SPECTROSCOPY; TRANSESTERIFICATION;

ACIDS; BIOCOMPATIBLE MATERIALS; HYDROLYSIS; MAGNETIC RESONANCE SPECTROSCOPY; POLYMERS; SPECTROPHOTOMETRY, INFRARED;

EID: 36849089627     PISSN: 15493296     EISSN: 15524965     Source Type: Journal    
DOI: 10.1002/jbm.a.31395     Document Type: Article

References (16)

1. Bremer J, Osmundensen H. Fatty acid oxidation and regulation. In: Numa SE, editor. Fatty Acid Metabolism and Its Regulation. Amsterdam: Elsevier; 1984. p 113-147.
2. Teomim D, Nyska A, Domb AJ. Ricinoleic acid-based biopolymers. J Biomed Mater Res 1999;45:258-267.
3. Krasko MY, Kumar N, Domb AJ. Protein and peptide release from in situ gelling polymer. Biomacromolecules 2006;7:2461-2463.
4. Shikanov A, Vaisman B, Krasko MY, Nyska A, Domb AJ. Poly(sebacic acid-coricinoleic acid) biodegradable carrier for paclitaxel: In vitro release and in vivo toxicity. J Biomed Mater Res A 2004;69:47-54.
5. Krasko MY, Shikanov A, Ezra A, Domb AJ. Poly(ester anhydride)s prepared by the insertion of ricinoleic acid into poly (sebacic acid). J Polym Sci Part A: Polym Chem 2003;41:1059-1069.
6. Krasko MY, Domb AJ. Hydrolytic degradation of ricinoleic-sebacic-ester- anhydride copolymers. Biomacromolecules 2005;6:1877-1884.
7. Krasko MY, Golenser J, Nyska A, Nyska M, Domb AJ. Gentamicin extended release from an injectable polymeric implant. J Control Release 2007;117(1):90-96.
8. Shikanov A, Domb AJ. Poly(sebacic acid-co-ricinoleic acid) biodegradable injectable in situ gelling polymer. Biomacromolecules 2006;7:288-296.
9. Borsotti G, Guglienlmetti G, Spera S, Battistel E. Synthesis of phosphatidylcholines containing ricinoleic acid. Tetrahedron 2001;57:10219-10227.
10. Domb AJ, Linden C, Polatcheck I, Benita S. Nystatin-dextran conjugates: Synthesis and characterization. J Polym Sci Part A: Polym Chem 1996;34:12291-1236.
11. Hatefi A, Amsden BJ. Biodegradable injectable in situ forming drug delivery systems. J Control Release 2002;80:9-28.
12. Jackson JK, Zhang X, Llewellen S, Hunter WL, Burt HM. The characterization of novel polymeric paste formulations for intratumoral delivery. Int J Pharmaceutics 2004;270:185-198.
13. Nivasu VM, Reddy TT, Tammishetti S. In situ polymerizable polyethyleneglycol containing polyesterpolyol acrylates for tissue sealant applications. Biomaterials 2004;25:3283-3291.
14. Graham PD, Brodbeck KJ, McHugh AJ. Phase in version dinamics of PLGA solutions related to drug delivery. J Control Release 1999;58:233-245.
15. Choi S, Kim SW. Controlled release of insulin from injectable biodegradable triblock copolymer depot in ZDF rats. Pharm Res 2003;20:2008-2010.
16. Engstrom S, Engstrom L. Phase behaviour of lidocain-monoolein-water system. Int J Pharm 1992;79:113-122.