Gentamicin extended release from an injectable polymeric implant

Journal of Controlled Release

Volumn 117, Issue 1, 2007, Pages 90-96

  Krasko, Michal Y ^a   Golenser, Jacob ^b   Nyska, Abraham ^c   Nyska, Meir ^d   Brin, Yaron S ^d   Domb, Abraham J ^a,e,f  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^c David R Bloom Center for Pharmacy ^*  (Israel)

^d MEIR MEDICAL CENTER   (Israel)

^e David R Bloom Center for Pharmacy   (Israel)

^f Alex Grass Center for Synthesis and Drug Design   (Israel)

Author keywords

Antibiotic; Gentamicin; Injectable polyner; Osteomyelitis; poly(ester anhydride); Staphylococcus aureus

Indexed keywords

GENTAMICIN; INJECTABLE POLYMERS; OSTEOMYELITIS; STAPHYLOCOCCUS AUREUS;

BIODEGRADATION; IMPLANTS (SURGICAL); POLYESTERS; POLYMERS; POLYMETHYL METHACRYLATES; TOXICITY;

ANTIBIOTICS;

ACID ANHYDRIDE; BUFFER; GENTAMICIN; POLY(SEBACIC ACID CO RICINOLEIC ACID ESTER ANHYDRIDE); POLYMER; UNCLASSIFIED DRUG;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL INFECTION; BIODEGRADABLE IMPLANT; CONTROLLED RELEASE FORMULATION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG FORMULATION; DRUG MONITORING; DRUG SCREENING; DRUG STABILITY; GAMMA IRRADIATION; HISTOPATHOLOGY; IMPLANTATION; IN VITRO STUDY; IN VIVO STUDY; INJECTION; INSTRUMENT STERILIZATION; MALE; NONHUMAN; OSTEOMYELITIS; PRIORITY JOURNAL; RAT; SHELF LIFE; STAPHYLOCOCCUS AUREUS; STORAGE;

ANIMALS; ANTI-BACTERIAL AGENTS; CHEMISTRY, PHARMACEUTICAL; DECANOIC ACIDS; DELAYED-ACTION PREPARATIONS; DRUG IMPLANTS; DRUG STABILITY; DRUG STORAGE; GAMMA RAYS; GENTAMICINS; INJECTIONS; MALE; MICROBIAL SENSITIVITY TESTS; MOLECULAR WEIGHT; OSTEOMYELITIS; POLYMERS; RATS; RATS, WISTAR; RICINOLEIC ACIDS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS; VISCOSITY;

EID: 33846573851     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.10.010     Document Type: Article

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