Group Up-and-Down Designs in Toxicity Studies

Statistical Methods for Dose-Finding Experiments

Volumn , Issue , 2006, Pages 115-130

  Ivanova, Anastasia ^a   Flournoy, Nancy ^b  

^a IL   (United States)

^b UNIVERSITY OF MISSOURI   (United States)

Author keywords

Empirical mean estimator; First order Markovian procedures; Fully sequential designs in phase I clinical trials; Group up and down design of Tsutakawa; Maximum likelihood estimator (MLE); Start up phase study and classical start up rule; Up and down designs; Up and down designs in toxicity studies

Indexed keywords

MAXIMUM LIKELIHOOD ESTIMATION;

FIRST ORDER MARKOVIAN; GROUP UP-AND-DOWN DESIGN OF TSUTAKAWA; IN-PHASE; MAXIMUM LIKELIHOOD ESTIMATORS (MLE); MEAN ESTIMATORS; START-UP PHASE; UP-AND-DOWN DESIGNS IN TOXICITY STUDIES;

TOXICITY;

EID: 36849076925     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/0470861258.ch5     Document Type: Chapter

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