Dose finding using the biased coin up-and-down design and isotonic regression

Biometrics

Volumn 58, Issue 1, 2002, Pages 171-177

  Stylianou, M ^a   Flournoy, N ^b  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b AMERICAN UNIVERSITY   (United States)

Author keywords

Adaptive designs; Inference for stochastic processes; Logistic regression; Quantal estimation; Random walk designs; Response driven designs; Toxicity studies

Indexed keywords

DECISION THEORY; MAXIMUM LIKELIHOOD ESTIMATION; MEAN SQUARE ERROR; RANDOM PROCESSES; REGRESSION ANALYSIS; STOCHASTIC SYSTEMS;

ADAPTIVE DESIGNS; DOSE FINDING; INFERENCE FOR STOCHASTIC PROCESS; ISOTONIC REGRESSION; LOGISTICS REGRESSIONS; QUANTAL ESTIMATION; RANDOM WALK; RANDOM WALK DESIGN; RESPONSE-DRIVEN DESIGN; TOXICITY STUDY;

TOXICITY;

BIOMETRY; ESTIMATION METHOD; TOXICITY;

ARTICLE; DOSE CALCULATION; HUMAN; LOGISTIC REGRESSION ANALYSIS; METHODOLOGY; QUANTITATIVE ANALYSIS; REGRESSION ANALYSIS; TOXICITY TESTING;

EID: 0036191646     PISSN: 0006341X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.0006-341X.2002.00171.x     Document Type: Article

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