-
1
-
-
11344253462
-
Increased incidence of thyroid carcinoma in France: A true epidemic or thyroid nodule management effects? Report from the French Thyroid Cancer Committee
-
Leenhardt L, Grosclaude P, Cherie-Challine L 2004 Increased incidence of thyroid carcinoma in France: a true epidemic or thyroid nodule management effects? Report from the French Thyroid Cancer Committee. Thyroid 14:1056-1060
-
(2004)
Thyroid
, vol.14
, pp. 1056-1060
-
-
Leenhardt, L.1
Grosclaude, P.2
Cherie-Challine, L.3
-
2
-
-
33646442046
-
Increasing incidence of thyroid cancer in the United States, 1973-2002
-
Davies L, Welch HG 2006 Increasing incidence of thyroid cancer in the United States, 1973-2002. JAMA 295:2164-2167
-
(2006)
JAMA
, vol.295
, pp. 2164-2167
-
-
Davies, L.1
Welch, H.G.2
-
3
-
-
33646472399
-
An overview of the management of thyroid cancer
-
Mazzaferri EL, Harmer C, Mallick UK, Kendall-Taylor P, eds, London: Springer-Verlag;
-
Mazzaferri EL 2007 An overview of the management of thyroid cancer. In: Mazzaferri EL, Harmer C, Mallick UK, Kendall-Taylor P, eds. Practical management of thyroid cancer: a multidisciplinary approach. London: Springer-Verlag; 1-28
-
(2007)
Practical management of thyroid cancer: A multidisciplinary approach
, pp. 1-28
-
-
Mazzaferri, E.L.1
-
4
-
-
85031437520
-
-
Ries LAG, Harkins D, Krapcho M, Mariotto A, Miller BA, Feuer EJ, Clegg L, Eisner MP, Horner MJ, Howlader N, Hayat M, Hankey BF, Edwards BK, eds. 2006 SEER cancer statistics review, 1975-2003. Bethesda, MD: National Cancer Institute (http://seer.cancer.gov/csr/1975_2003/. based on November 2005 SEER data submission, posted to the SEER web site, 2006)
-
Ries LAG, Harkins D, Krapcho M, Mariotto A, Miller BA, Feuer EJ, Clegg L, Eisner MP, Horner MJ, Howlader N, Hayat M, Hankey BF, Edwards BK, eds. 2006 SEER cancer statistics review, 1975-2003. Bethesda, MD: National Cancer Institute (http://seer.cancer.gov/csr/1975_2003/. based on November 2005 SEER data submission, posted to the SEER web site, 2006)
-
-
-
-
5
-
-
0032535770
-
A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995
-
Hundahl SA, Fleming ID, Fremgen AM, Menck HR 1998 A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995. Cancer 83:2638-2648
-
(1998)
Cancer
, vol.83
, pp. 2638-2648
-
-
Hundahl, S.A.1
Fleming, I.D.2
Fremgen, A.M.3
Menck, H.R.4
-
6
-
-
12944271053
-
Cancer statistics, 2005
-
Jemal A, Murray T, Ward E, Samuels A, Tiwari RC, Ghafoor A, Feuer EJ, Thun MJ 2005 Cancer statistics, 2005. CA Cancer J Clin 55:10-30
-
(2005)
CA Cancer J Clin
, vol.55
, pp. 10-30
-
-
Jemal, A.1
Murray, T.2
Ward, E.3
Samuels, A.4
Tiwari, R.C.5
Ghafoor, A.6
Feuer, E.J.7
Thun, M.J.8
-
8
-
-
27144526198
-
Mitogen-activated protein kinases in cell-cycle control
-
MacCorkle RA, Tan TH 2005 Mitogen-activated protein kinases in cell-cycle control. Cell Biochem Biophys 43:451-461
-
(2005)
Cell Biochem Biophys
, vol.43
, pp. 451-461
-
-
MacCorkle, R.A.1
Tan, T.H.2
-
9
-
-
0038697566
-
Raf proteins and cancer: B-Raf is identified as a mutational target
-
Mercer KE, Pritchard CA 2003 Raf proteins and cancer: B-Raf is identified as a mutational target. Biochim Biophys Acta 1653:25-40
-
(2003)
Biochim Biophys Acta
, vol.1653
, pp. 25-40
-
-
Mercer, K.E.1
Pritchard, C.A.2
-
10
-
-
2442615800
-
MEK inhibitors: A therapeutic approach to targeting the Ras-MAP kinase pathway in tumors
-
Sebolt-Leopold JS 2004 MEK inhibitors: a therapeutic approach to targeting the Ras-MAP kinase pathway in tumors. Curr Pharm Des 10:1907-1914
-
(2004)
Curr Pharm Des
, vol.10
, pp. 1907-1914
-
-
Sebolt-Leopold, J.S.1
-
11
-
-
33746434378
-
Cancer targets in the Ras pathway
-
Rodriguez-Viciana P, Tetsu O, Oda K, Okada J, Rauen K, McCormick F 2005 Cancer targets in the Ras pathway. Cold Spring Harb Symp Quant Biol 70:461-467
-
(2005)
Cold Spring Harb Symp Quant Biol
, vol.70
, pp. 461-467
-
-
Rodriguez-Viciana, P.1
Tetsu, O.2
Oda, K.3
Okada, J.4
Rauen, K.5
McCormick, F.6
-
12
-
-
33646399160
-
Targeting the ERK signaling pathway in cancer therapy
-
Kohno M, Pouyssegur J 2006 Targeting the ERK signaling pathway in cancer therapy. Ann Med 38:200-211
-
(2006)
Ann Med
, vol.38
, pp. 200-211
-
-
Kohno, M.1
Pouyssegur, J.2
-
13
-
-
33646828701
-
Genetics of papillary thyroid cancer initiation: Implications for therapy
-
Fagin JA 2005 Genetics of papillary thyroid cancer initiation: implications for therapy. Trans Am Clin Climatol Assoc 116:259-269
-
(2005)
Trans Am Clin Climatol Assoc
, vol.116
, pp. 259-269
-
-
Fagin, J.A.1
-
14
-
-
21244457181
-
BRAF mutation in thyroid cancer
-
Xing M 2005 BRAF mutation in thyroid cancer. Endocr Relat Cancer 12:245-262
-
(2005)
Endocr Relat Cancer
, vol.12
, pp. 245-262
-
-
Xing, M.1
-
15
-
-
28044443680
-
Alterations of the BRAF gene in thyroid tumors
-
Ciampi R, Nikiforov YE 2005 Alterations of the BRAF gene in thyroid tumors. Endocr Pathol 16:163-172
-
(2005)
Endocr Pathol
, vol.16
, pp. 163-172
-
-
Ciampi, R.1
Nikiforov, Y.E.2
-
16
-
-
33645307434
-
Pathogenetic mechanisms in thyroid follicular-cell neoplasia
-
Kondo T, Ezzat S, Asa SL 2006 Pathogenetic mechanisms in thyroid follicular-cell neoplasia. Nat Rev Cancer 6:292-306
-
(2006)
Nat Rev Cancer
, vol.6
, pp. 292-306
-
-
Kondo, T.1
Ezzat, S.2
Asa, S.L.3
-
17
-
-
33645683121
-
Is BRAF the Achilles' heel of thyroid cancer?
-
Chiloeches A, Marais R 2006 Is BRAF the Achilles' heel of thyroid cancer? Clin Cancer Res 12:1661-1664
-
(2006)
Clin Cancer Res
, vol.12
, pp. 1661-1664
-
-
Chiloeches, A.1
Marais, R.2
-
18
-
-
0242468891
-
CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK)
-
Allen LF, Sebolt-Leopold J, Meyer MB 2003 CI-1040 (PD184352), a targeted signal transduction inhibitor of MEK (MAPKK). Semin Oncol 30:105-116
-
(2003)
Semin Oncol
, vol.30
, pp. 105-116
-
-
Allen, L.F.1
Sebolt-Leopold, J.2
Meyer, M.B.3
-
19
-
-
14844285975
-
Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer
-
Rinehart J, Adjei AA, Lorusso PM, Waterhouse D, Hecht JR, Natale RB, Hamid O, Varterasian M, Asbury P, Kaldjian EP, Gulyas S, Mitchell DY, Herrera R, Sebolt-Leopold JS, Meyer MB 2004 Multicenter phase II study of the oral MEK inhibitor, CI-1040, in patients with advanced non-small-cell lung, breast, colon, and pancreatic cancer. J Clin Oncol 22:4456-4462
-
(2004)
J Clin Oncol
, vol.22
, pp. 4456-4462
-
-
Rinehart, J.1
Adjei, A.A.2
Lorusso, P.M.3
Waterhouse, D.4
Hecht, J.R.5
Natale, R.B.6
Hamid, O.7
Varterasian, M.8
Asbury, P.9
Kaldjian, E.P.10
Gulyas, S.11
Mitchell, D.Y.12
Herrera, R.13
Sebolt-Leopold, J.S.14
Meyer, M.B.15
-
20
-
-
23944439944
-
Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies
-
Lorusso PM, Adjei AA, Varterasian M, Gadgeel S, Reid J, Mitchell DY, Hanson L, DeLuca P, Bruzek L, Piens J, Asbury P, Van Becelaere K, Herrera R, Sebolt-Leopold J, Meyer MB 2005 Phase I and pharmacodynamic study of the oral MEK inhibitor CI-1040 in patients with advanced malignancies. J Clin Oncol 23:5281-5293
-
(2005)
J Clin Oncol
, vol.23
, pp. 5281-5293
-
-
Lorusso, P.M.1
Adjei, A.A.2
Varterasian, M.3
Gadgeel, S.4
Reid, J.5
Mitchell, D.Y.6
Hanson, L.7
DeLuca, P.8
Bruzek, L.9
Piens, J.10
Asbury, P.11
Van Becelaere, K.12
Herrera, R.13
Sebolt-Leopold, J.14
Meyer, M.B.15
-
21
-
-
31144453233
-
BRAF mutation predicts sensitivity to MEK inhibition
-
Solit DB, Garraway LA, Pratilas CA, Sawai A, Getz G, Basso A, Ye Q, Lobo JM, She Y, Osman I, Golub TR, Sebolt-Leopold J, Sellers WR, Rosen N 2006 BRAF mutation predicts sensitivity to MEK inhibition. Nature 439:358-362
-
(2006)
Nature
, vol.439
, pp. 358-362
-
-
Solit, D.B.1
Garraway, L.A.2
Pratilas, C.A.3
Sawai, A.4
Getz, G.5
Basso, A.6
Ye, Q.7
Lobo, J.M.8
She, Y.9
Osman, I.10
Golub, T.R.11
Sebolt-Leopold, J.12
Sellers, W.R.13
Rosen, N.14
-
22
-
-
0028355893
-
Determination of median lethal and infectious doses in animal model systems
-
Welkos S, O'Brien A 1994 Determination of median lethal and infectious doses in animal model systems. Methods Enzymol 235:29-39
-
(1994)
Methods Enzymol
, vol.235
, pp. 29-39
-
-
Welkos, S.1
O'Brien, A.2
-
23
-
-
18144427143
-
Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors
-
Gray MJ, Wey JS, Belcheva A, McCarty MF, Trevino JG, Evans DB, Ellis LM, Gallick GE 2005 Neuropilin-1 suppresses tumorigenic properties in a human pancreatic adenocarcinoma cell line lacking neuropilin-1 coreceptors. Cancer Res 65:3664-3670
-
(2005)
Cancer Res
, vol.65
, pp. 3664-3670
-
-
Gray, M.J.1
Wey, J.S.2
Belcheva, A.3
McCarty, M.F.4
Trevino, J.G.5
Evans, D.B.6
Ellis, L.M.7
Gallick, G.E.8
-
24
-
-
0033378227
-
Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden
-
Katzenstein HM, Rademaker AW, Senger C, Salwen HR, Nguyen NN, Thorner PS, Litsas L, Cohn SL 1999 Effectiveness of the angiogenesis inhibitor TNP-470 in reducing the growth of human neuroblastoma in nude mice inversely correlates with tumor burden. Clin Cancer Res 5:4273-4278
-
(1999)
Clin Cancer Res
, vol.5
, pp. 4273-4278
-
-
Katzenstein, H.M.1
Rademaker, A.W.2
Senger, C.3
Salwen, H.R.4
Nguyen, N.N.5
Thorner, P.S.6
Litsas, L.7
Cohn, S.L.8
-
26
-
-
18444374405
-
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA 2002 Mutations of the BRAF gene in human cancer. Nature 417:949-954
-
Davies H, Bignell GR, Cox C, Stephens P, Edkins S, Clegg S, Teague J, Woffendin H, Garnett MJ, Bottomley W, Davis N, Dicks E, Ewing R, Floyd Y, Gray K, Hall S, Hawes R, Hughes J, Kosmidou V, Menzies A, Mould C, Parker A, Stevens C, Watt S, Hooper S, Wilson R, Jayatilake H, Gusterson BA, Cooper C, Shipley J, Hargrave D, Pritchard-Jones K, Maitland N, Chenevix-Trench G, Riggins GJ, Bigner DD, Palmieri G, Cossu A, Flanagan A, Nicholson A, Ho JW, Leung SY, Yuen ST, Weber BL, Seigler HF, Darrow TL, Paterson H, Marais R, Marshall CJ, Wooster R, Stratton MR, Futreal PA 2002 Mutations of the BRAF gene in human cancer. Nature 417:949-954
-
-
-
-
27
-
-
20144372793
-
Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation
-
Knauf JA, Ma X, Smith EP, Zhang L, Mitsutake N, Liao XH, Refetoff S, Nikiforov YE, Fagin JA 2005 Targeted expression of BRAFV600E in thyroid cells of transgenic mice results in papillary thyroid cancers that undergo dedifferentiation. Cancer Res 65:4238-4245
-
(2005)
Cancer Res
, vol.65
, pp. 4238-4245
-
-
Knauf, J.A.1
Ma, X.2
Smith, E.P.3
Zhang, L.4
Mitsutake, N.5
Liao, X.H.6
Refetoff, S.7
Nikiforov, Y.E.8
Fagin, J.A.9
-
28
-
-
21644440921
-
Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery
-
Thompson N, Lyons J 2005 Recent progress in targeting the Raf/MEK/ERK pathway with inhibitors in cancer drug discovery. Curr Opin Pharmacol 5:350-356
-
(2005)
Curr Opin Pharmacol
, vol.5
, pp. 350-356
-
-
Thompson, N.1
Lyons, J.2
-
29
-
-
0026761580
-
A biochemical hallmark of apoptosis: Internucleosomal degradation of the genome
-
Compton MM 1992 A biochemical hallmark of apoptosis: internucleosomal degradation of the genome. Cancer Metastasis Rev 11:105-119
-
(1992)
Cancer Metastasis Rev
, vol.11
, pp. 105-119
-
-
Compton, M.M.1
-
30
-
-
0031298259
-
Cleavage of poly(ADP-ribose) polymerase: A sensitive parameter to study cell death
-
Duriez PJ, Shah GM 1997 Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death. Biochem Cell Biol 75:337-349
-
(1997)
Biochem Cell Biol
, vol.75
, pp. 337-349
-
-
Duriez, P.J.1
Shah, G.M.2
-
31
-
-
0029786329
-
Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway
-
Lavoie JN, L'Allemain G, Brunet A, Muller R, Pouyssegur J 1996 Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway. J Biol Chem 271:20608-20616
-
(1996)
J Biol Chem
, vol.271
, pp. 20608-20616
-
-
Lavoie, J.N.1
L'Allemain, G.2
Brunet, A.3
Muller, R.4
Pouyssegur, J.5
-
32
-
-
0032477854
-
Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1)
-
Cheng M, Sexl V, Sherr CJ, Roussel MF 1998 Assembly of cyclin D-dependent kinase and titration of p27Kip1 regulated by mitogen-activated protein kinase kinase (MEK1). Proc Natl Acad Sci USA 95:1091-1096
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 1091-1096
-
-
Cheng, M.1
Sexl, V.2
Sherr, C.J.3
Roussel, M.F.4
-
33
-
-
0034632702
-
The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway
-
Saavedra HI, Knauf JA, Shirokawa JM, Wang J, Ouyang B, Elisei R, Stambrook PJ, Fagin JA 2000 The RAS oncogene induces genomic instability in thyroid PCCL3 cells via the MAPK pathway. Oncogene 19:3948-3954
-
(2000)
Oncogene
, vol.19
, pp. 3948-3954
-
-
Saavedra, H.I.1
Knauf, J.A.2
Shirokawa, J.M.3
Wang, J.4
Ouyang, B.5
Elisei, R.6
Stambrook, P.J.7
Fagin, J.A.8
-
34
-
-
16844367605
-
Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells
-
Mitsutake N, Knauf JA, Mitsutake S, Mesa Jr C, Zhang L, Fagin JA 2005 Conditional BRAFV600E expression induces DNA synthesis, apoptosis, dedifferentiation, and chromosomal instability in thyroid PCCL3 cells. Cancer Res 65:2465-2473
-
(2005)
Cancer Res
, vol.65
, pp. 2465-2473
-
-
Mitsutake, N.1
Knauf, J.A.2
Mitsutake, S.3
Mesa Jr, C.4
Zhang, L.5
Fagin, J.A.6
-
35
-
-
20144387455
-
The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells
-
Melillo RM, Castellone MD, Guarino V, De Falco V, Cirafici AM, Salvatore G, Caiazzo F, Basolo F, Giannini R, Kruhoffer M, Orntoft T, Fusco A, Santoro M 2005 The RET/PTC-RAS-BRAF linear signaling cascade mediates the motile and mitogenic phenotype of thyroid cancer cells. J Clin Invest 115:1068-1081
-
(2005)
J Clin Invest
, vol.115
, pp. 1068-1081
-
-
Melillo, R.M.1
Castellone, M.D.2
Guarino, V.3
De Falco, V.4
Cirafici, A.M.5
Salvatore, G.6
Caiazzo, F.7
Basolo, F.8
Giannini, R.9
Kruhoffer, M.10
Orntoft, T.11
Fusco, A.12
Santoro, M.13
-
36
-
-
33947290100
-
Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant
-
Liu D, Hu S, Hou P, Jiang D, Condouris S, Xing M 2007 Suppression of BRAF/MEK/MAP kinase pathway restores expression of iodide-metabolizing genes in thyroid cells expressing the V600E BRAF mutant. Clin Cancer Res 13:1341-1349
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1341-1349
-
-
Liu, D.1
Hu, S.2
Hou, P.3
Jiang, D.4
Condouris, S.5
Xing, M.6
-
37
-
-
0027943619
-
Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer
-
Mazzaferri EL, Jhiang SM 1994 Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer. Am J Med 97:418-428
-
(1994)
Am J Med
, vol.97
, pp. 418-428
-
-
Mazzaferri, E.L.1
Jhiang, S.M.2
-
39
-
-
33845399067
-
Pathology and genetics of thyroid carcinoma
-
DeLellis RA 2006 Pathology and genetics of thyroid carcinoma. J Surg Oncol 94:662-669
-
(2006)
J Surg Oncol
, vol.94
, pp. 662-669
-
-
DeLellis, R.A.1
-
40
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
Sebolt-Leopold JS, Dudley DT, Herrera R, Van Becelaere K, Wiland A, Gowan RC, Tecle H, Barrett SD, Bridges A, Przybranowski S, Leopold WR, Saltiel AR 1999 Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med 5:810-816
-
(1999)
Nat Med
, vol.5
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
Van Becelaere, K.4
Wiland, A.5
Gowan, R.C.6
Tecle, H.7
Barrett, S.D.8
Bridges, A.9
Przybranowski, S.10
Leopold, W.R.11
Saltiel, A.R.12
-
42
-
-
33750168399
-
Current concepts in RET-related genetics, signaling and therapeutics
-
Plaza-Menacho I, Burzynski GM, de Groot JW, Eggen BJ, Hofstra RM 2006 Current concepts in RET-related genetics, signaling and therapeutics. Trends Genet 22:627-636
-
(2006)
Trends Genet
, vol.22
, pp. 627-636
-
-
Plaza-Menacho, I.1
Burzynski, G.M.2
de Groot, J.W.3
Eggen, B.J.4
Hofstra, R.M.5
-
43
-
-
34249993765
-
Integrative genomic approaches identify IKBKE as a breast cancer oncogene
-
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC 2007 Integrative genomic approaches identify IKBKE as a breast cancer oncogene. Cell 129:1065-1079
-
(2007)
Cell
, vol.129
, pp. 1065-1079
-
-
Boehm, J.S.1
Zhao, J.J.2
Yao, J.3
Kim, S.Y.4
Firestein, R.5
Dunn, I.F.6
Sjostrom, S.K.7
Garraway, L.A.8
Weremowicz, S.9
Richardson, A.L.10
Greulich, H.11
Stewart, C.J.12
Mulvey, L.A.13
Shen, R.R.14
Ambrogio, L.15
Hirozane-Kishikawa, T.16
Hill, D.E.17
Vidal, M.18
Meyerson, M.19
Grenier, J.K.20
Hinkle, G.21
Root, D.E.22
Roberts, T.M.23
Lander, E.S.24
Polyak, K.25
Hahn, W.C.26
more..
-
44
-
-
16444378374
-
Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations
-
Pohl G, Ho CL, Kurman RJ, Bristow R, Wang TL, Shih I 2005 Inactivation of the mitogen-activated protein kinase pathway as a potential target-based therapy in ovarian serous tumors with KRAS or BRAF mutations. Cancer Res 65:1994-2000
-
(2005)
Cancer Res
, vol.65
, pp. 1994-2000
-
-
Pohl, G.1
Ho, C.L.2
Kurman, R.J.3
Bristow, R.4
Wang, T.L.5
Shih, I.6
-
45
-
-
11244304215
-
BRAF and endocrine tumors: Mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors
-
Perren A, Schmid S, Locher T, Saremaslani P, Bonvin C, Heitz PU, Komminoth P 2004 BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors. Endocr Relat Cancer 11:855-860
-
(2004)
Endocr Relat Cancer
, vol.11
, pp. 855-860
-
-
Perren, A.1
Schmid, S.2
Locher, T.3
Saremaslani, P.4
Bonvin, C.5
Heitz, P.U.6
Komminoth, P.7
-
46
-
-
33646791858
-
Uncommon V599E BRAF mutations in Japanese patients with lung cancer
-
Sasaki H, Kawano O, Endo K, Suzuki E, Haneda H, Yukiue H, Kobayashi Y, Yano M, Fujii Y 2006 Uncommon V599E BRAF mutations in Japanese patients with lung cancer. J Surg Res 133:203-206
-
(2006)
J Surg Res
, vol.133
, pp. 203-206
-
-
Sasaki, H.1
Kawano, O.2
Endo, K.3
Suzuki, E.4
Haneda, H.5
Yukiue, H.6
Kobayashi, Y.7
Yano, M.8
Fujii, Y.9
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