Dearomatizing anionic cyclization of N-alkyl-N-benzyl(dinaphthyl) phosphinamides. A facile route to γ-(amino)dihydronaphthalenylphosphinic acids

Journal of Organic Chemistry

Volumn 72, Issue 25, 2007, Pages 9704-9712

  Ruiz Gómez, Gloria ^a   Iglesias, María José ^a   Serrano Ruiz, Manuel ^a   López Ortiz, Fernando ^a  

^a UNIVERSITY OF ALMERÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

DEAROMATIZING ANIONIC CYCLIZATION; DIASTEREOSELECTIVITY; ELECTROPHILES; MICROMOLAR SCALE;

AMIDES; AMINO ACIDS; BENZENE; BIOACTIVITY; CELLS; CYCLIZATION; OPTIMIZATION; SYNTHESIS (CHEMICAL); TUMORS;

AROMATIC COMPOUNDS;

AMIDE; AMINO ACID; BROMINE DERIVATIVE; HETEROCYCLIC COMPOUND; NAPHTHALENE DERIVATIVE; NAPHTHALENYL GAMMA AMINOPHOSPHINIC ACID; OXIDE; PHOSPHINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; AROMATIZATION; ARTICLE; BIOLOGICAL ACTIVITY; CANCER INHIBITION; CELL STRAIN K 562; CELL STRAIN LNCAP; CHEMICAL REACTION; CHEMICAL STRUCTURE; CONTROLLED STUDY; CYCLIZATION; FEASIBILITY STUDY; FEMALE; HELA CELL; HUMAN; HUMAN CELL; HYDROLYSIS; MALE; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; REACTION TIME; STEREOCHEMISTRY; SYNTHESIS; TEMPERATURE; TUMOR CELL LINE;

AMIDES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYCLIZATION; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR CONFORMATION; ORGANOPHOSPHORUS COMPOUNDS; PHOSPHINIC ACIDS; STEREOISOMERISM;

EID: 36849059697     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo701607s     Document Type: Article

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