Is a Positive Bladder Neck Margin Truly a T4 Lesion in the Prostate Specific Antigen Era? Results From the SEARCH Database

Journal of Urology

Volumn 179, Issue 1, 2008, Pages 124-129

  Buschemeyer III, W Cooper ^a   Hamilton, Robert J ^a   Aronson, William J ^a   Presti Jr , Joseph C ^a   Terris, Martha K ^a   Kane, Christopher J ^a   Amling, Christopher L ^a   Freedland, Stephen J ^a  

^a DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

bladder; neoplasm staging; prostate; prostatectomy; prostatic neoplasms

Indexed keywords

PROSTATE SPECIFIC ANTIGEN;

ADULT; ARTICLE; BLADDER NECK; CLINICAL FEATURE; CONFIDENCE INTERVAL; CONTROLLED STUDY; GLEASON SCORE; HUMAN; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; PROSTATECTOMY; RECURRENCE RISK; SEMINAL VESICLE;

DATABASES, FACTUAL; HUMANS; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; NEOPLASM STAGING; NEOPLASMS, SECOND PRIMARY; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS; URINARY BLADDER;

EID: 36849055557     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.juro.2007.08.130     Document Type: Article

References (13)

1. Greene F.L., Page D.L., and Fleming I.D. AJCC Cancer Staging Manual. 6th ed. (2002), Springer-Verlag, New York
2. Blute M.L., Bostwick D.G., Bergstralh E.J., Slezak J.M., Martin S.K., Amling C.L., et al. Anatomic site-specific positive margins in organ-confined prostate cancer and its impact on outcome after radical prostatectomy. Urology 50 (1997) 733
3. Dash A., Sanda M.G., Yu M., Taylor J.M., Fecko A., and Rubin M.A. Prostate cancer involving the bladder neck: recurrence-free survival and implications for AJCC staging modification. American Joint Committee on Cancer. Urology 60 (2002) 276
4. Obek C., Sadek S., Lai S., Civantos F., Rubinowicz D., and Soloway M.S. Positive surgical margins with radical retropubic prostatectomy: anatomic site-specific pathologic analysis and impact on prognosis. Urology 54 (1999) 682
5. Poulos C.K., Koch M.O., Eble J.N., Daggy J.K., and Cheng L. Bladder neck invasion is an independent predictor of prostate-specific antigen recurrence. Cancer 101 (2004) 1563
6. Yossepowitch O., Engelstein D., Konichezky M., Sella A., Livne P.M., and Baniel J. Bladder neck involvement at radical prostatectomy: positive margins or advanced T4 disease?. Urology 56 (2000) 448
7. Yossepowitch O., Sircar K., Scardino P.T., Ohori M., Kattan M.W., Wheeler T.M., et al. Bladder neck involvement in pathological stage pT4 radical prostatectomy specimens is not an independent prognostic factor. J Urol 168 (2002) 2011
8. Watson R.B., Civantos F., and Soloway M.S. Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis. Urology 48 (1996) 80
9. Concato J., Feinstein A.R., and Holford T.R. The risk of determining risk with multivariable models. Ann Intern Med 118 (1993) 201
10. Freedland S.J., Amling C.L., Dorey F., Kane C.J., Presti Jr. J.C., Terris M.K., et al. Race as an outcome predictor after radical prostatectomy: results from the Shared Equal Access Regional Cancer Hospital (SEARCH) database. Urology 60 (2002) 670
11. Hall G.S., Kramer C.E., and Epstein J.I. Evaluation of radical prostatectomy specimens. a comparative analysis of sampling methods. Am J Surg Pathol 16 (1992) 315
12. Freedland S.J., Aronson W., Presti Jr. J.C., Kane C.J., Terris M.K., Elashoff D., et al. Should a positive surgical margin following radical prostatectomy be pathological stage T2 or T3?. Results from the SEARCH database. J Urol 169 (2003) 2142
13. Aydin H., Tsuzuki T., Hernandez D., Walsh P.C., Partin A.W., and Epstein J.I. Positive proximal (bladder neck) margin at radical prostatectomy confers greater risk of biochemical progression. Urology 64 (2004) 551