메뉴 건너뛰기




Volumn 19, Issue 6, 2007, Pages 611-614

Toll-like receptors: paving the path to T cell-driven autoimmunity?

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; TOLL LIKE RECEPTOR;

EID: 36849048443     PISSN: 09527915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.coi.2007.07.022     Document Type: Review
Times cited : (29)

References (32)
  • 4
    • 33947204489 scopus 로고    scopus 로고
    • TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis
    • This study shows that CpG can act directly upon T cells to support survival and proliferation in the absence of Protein Kinase C-theta.
    • Marsland B.J., Nembrini C., Grun K., Reissmann R., Kurrer M., Leipner C., and Kopf M. TLR ligands act directly upon T cells to restore proliferation in the absence of protein kinase C-theta signaling and promote autoimmune myocarditis. J Immunol 178 (2007) 3466-3473. This study shows that CpG can act directly upon T cells to support survival and proliferation in the absence of Protein Kinase C-theta.
    • (2007) J Immunol , vol.178 , pp. 3466-3473
    • Marsland, B.J.1    Nembrini, C.2    Grun, K.3    Reissmann, R.4    Kurrer, M.5    Leipner, C.6    Kopf, M.7
  • 5
    • 33750369226 scopus 로고    scopus 로고
    • Toll-like receptors in systemic autoimmune disease
    • Marshak-Rothstein A. Toll-like receptors in systemic autoimmune disease. Nat Rev Immunol 6 (2006) 823-835
    • (2006) Nat Rev Immunol , vol.6 , pp. 823-835
    • Marshak-Rothstein, A.1
  • 6
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 1 (2001) 135-145
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 8
    • 0037450804 scopus 로고    scopus 로고
    • Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide
    • Caramalho I., Lopes-Carvalho T., Ostler D., Zelenay S., Haury M., and Demengeot J. Regulatory T cells selectively express Toll-like receptors and are activated by lipopolysaccharide. J Exp Med 197 (2003) 403-411
    • (2003) J Exp Med , vol.197 , pp. 403-411
    • Caramalho, I.1    Lopes-Carvalho, T.2    Ostler, D.3    Zelenay, S.4    Haury, M.5    Demengeot, J.6
  • 9
    • 0036570169 scopus 로고    scopus 로고
    • Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
    • Hornung V., Rothenfusser S., Britsch S., Krug A., Jahrsdorfer B., Giese T., Endres S., and Hartmann G. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 168 (2002) 4531-4537
    • (2002) J Immunol , vol.168 , pp. 4531-4537
    • Hornung, V.1    Rothenfusser, S.2    Britsch, S.3    Krug, A.4    Jahrsdorfer, B.5    Giese, T.6    Endres, S.7    Hartmann, G.8
  • 10
    • 0037080024 scopus 로고    scopus 로고
    • Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines
    • Zarember K.A., and Godowski P.J. Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines. J Immunol 168 (2002) 554-561
    • (2002) J Immunol , vol.168 , pp. 554-561
    • Zarember, K.A.1    Godowski, P.J.2
  • 11
    • 32444432610 scopus 로고    scopus 로고
    • Toll-like receptor 2 controls expansion and function of regulatory T cells
    • This study together with reference 12 shows convincing data that TLR2 signaling directly influences regulatory T cell expansion but question whether LPS can influence T cell function directly.
    • Sutmuller R.P., den Brok M.H., Kramer M., Bennink E.J., Toonen L.W., Kullberg B.J., Joosten L.A., Akira S., Netea M.G., and Adema G.J. Toll-like receptor 2 controls expansion and function of regulatory T cells. J Clin Invest 116 (2006) 485-494. This study together with reference 12 shows convincing data that TLR2 signaling directly influences regulatory T cell expansion but question whether LPS can influence T cell function directly.
    • (2006) J Clin Invest , vol.116 , pp. 485-494
    • Sutmuller, R.P.1    den Brok, M.H.2    Kramer, M.3    Bennink, E.J.4    Toonen, L.W.5    Kullberg, B.J.6    Joosten, L.A.7    Akira, S.8    Netea, M.G.9    Adema, G.J.10
  • 12
    • 33646487278 scopus 로고    scopus 로고
    • Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells
    • See comments for reference [11].
    • Liu H., Komai-Koma M., Xu D., and Liew F.Y. Toll-like receptor 2 signaling modulates the functions of CD4+ CD25+ regulatory T cells. Proc Natl Acad Sci USA 103 (2006) 7048-7053. See comments for reference [11].
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7048-7053
    • Liu, H.1    Komai-Koma, M.2    Xu, D.3    Liew, F.Y.4
  • 14
    • 33847388462 scopus 로고    scopus 로고
    • Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways
    • Sawaki J., Tsutsui H., Hayashi N., Yasuda K., Akira S., Tanizawa T., and Nakanishi K. Type 1 cytokine/chemokine production by mouse NK cells following activation of their TLR/MyD88-mediated pathways. Int Immunol 19 (2007) 311-320
    • (2007) Int Immunol , vol.19 , pp. 311-320
    • Sawaki, J.1    Tsutsui, H.2    Hayashi, N.3    Yasuda, K.4    Akira, S.5    Tanizawa, T.6    Nakanishi, K.7
  • 15
    • 33750470437 scopus 로고    scopus 로고
    • The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity
    • Lauzon N.M., Mian F., MacKenzie R., and Ashkar A.A. The direct effects of Toll-like receptor ligands on human NK cell cytokine production and cytotoxicity. Cell Immunol 241 (2006) 102-112
    • (2006) Cell Immunol , vol.241 , pp. 102-112
    • Lauzon, N.M.1    Mian, F.2    MacKenzie, R.3    Ashkar, A.A.4
  • 16
    • 31144458579 scopus 로고    scopus 로고
    • Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes
    • Wesch D., Beetz S., Oberg H.H., Marget M., Krengel K., and Kabelitz D. Direct costimulatory effect of TLR3 ligand poly(I:C) on human gamma delta T lymphocytes. J Immunol 176 (2006) 1348-1354
    • (2006) J Immunol , vol.176 , pp. 1348-1354
    • Wesch, D.1    Beetz, S.2    Oberg, H.H.3    Marget, M.4    Krengel, K.5    Kabelitz, D.6
  • 18
    • 0035175549 scopus 로고    scopus 로고
    • Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung
    • Chen H.D., Fraire A.E., Joris I., Brehm M.A., Welsh R.M., and Selin L.K. Memory CD8+ T cells in heterologous antiviral immunity and immunopathology in the lung. Nat Immunol 2 (2001) 1067-1076
    • (2001) Nat Immunol , vol.2 , pp. 1067-1076
    • Chen, H.D.1    Fraire, A.E.2    Joris, I.3    Brehm, M.A.4    Welsh, R.M.5    Selin, L.K.6
  • 19
    • 0034613727 scopus 로고    scopus 로고
    • Influenza virus lung infection protects from respiratory syncytial virus-induced immunopathology
    • Walzl G., Tafuro S., Moss P., Openshaw P.J., and Hussell T. Influenza virus lung infection protects from respiratory syncytial virus-induced immunopathology. J Exp Med 192 (2000) 1317-1326
    • (2000) J Exp Med , vol.192 , pp. 1317-1326
    • Walzl, G.1    Tafuro, S.2    Moss, P.3    Openshaw, P.J.4    Hussell, T.5
  • 20
    • 22544450733 scopus 로고    scopus 로고
    • Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells
    • Caron G., Duluc D., Fremaux I., Jeannin P., David C., Gascan H., and Delneste Y. Direct stimulation of human T cells via TLR5 and TLR7/8: flagellin and R-848 up-regulate proliferation and IFN-gamma production by memory CD4+ T cells. J Immunol 175 (2005) 1551-1557
    • (2005) J Immunol , vol.175 , pp. 1551-1557
    • Caron, G.1    Duluc, D.2    Fremaux, I.3    Jeannin, P.4    David, C.5    Gascan, H.6    Delneste, Y.7
  • 21
    • 1542297739 scopus 로고    scopus 로고
    • TLR2 is expressed on activated T cells as a costimulatory receptor
    • Komai-Koma M., Jones L., Ogg G.S., Xu D., and Liew F.Y. TLR2 is expressed on activated T cells as a costimulatory receptor. Proc Natl Acad Sci USA 101 (2004) 3029-3034
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 3029-3034
    • Komai-Koma, M.1    Jones, L.2    Ogg, G.S.3    Xu, D.4    Liew, F.Y.5
  • 22
    • 2442592788 scopus 로고    scopus 로고
    • Toll-like receptor ligands directly promote activated CD4+ T cell survival
    • Gelman A.E., Zhang J., Choi Y., and Turka L.A. Toll-like receptor ligands directly promote activated CD4+ T cell survival. J Immunol 172 (2004) 6065-6073
    • (2004) J Immunol , vol.172 , pp. 6065-6073
    • Gelman, A.E.1    Zhang, J.2    Choi, Y.3    Turka, L.A.4
  • 24
    • 33846122035 scopus 로고    scopus 로고
    • The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation
    • This study shows that CpG mediates T cell survival and proliferation through distinct MyD88 motifs.
    • Gelman A.E., LaRosa D.F., Zhang J., Walsh P.T., Choi Y., Sunyer J.O., and Turka L.A. The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4+ T cells and enables CpG oligodeoxynucleotide-mediated costimulation. Immunity 25 (2006) 783-793. This study shows that CpG mediates T cell survival and proliferation through distinct MyD88 motifs.
    • (2006) Immunity , vol.25 , pp. 783-793
    • Gelman, A.E.1    LaRosa, D.F.2    Zhang, J.3    Walsh, P.T.4    Choi, Y.5    Sunyer, J.O.6    Turka, L.A.7
  • 28
    • 29144534608 scopus 로고    scopus 로고
    • Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells
    • Crellin N.K., Garcia R.V., Hadisfar O., Allan S.E., Steiner T.S., and Levings M.K. Human CD4+ T cells express TLR5 and its ligand flagellin enhances the suppressive capacity and expression of FOXP3 in CD4+CD25+ T regulatory cells. J Immunol 175 (2005) 8051-8059
    • (2005) J Immunol , vol.175 , pp. 8051-8059
    • Crellin, N.K.1    Garcia, R.V.2    Hadisfar, O.3    Allan, S.E.4    Steiner, T.S.5    Levings, M.K.6
  • 29
    • 33847125247 scopus 로고    scopus 로고
    • Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression
    • Wan Y.Y., and Flavell R.A. Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression. Nature 445 (2007) 766-770
    • (2007) Nature , vol.445 , pp. 766-770
    • Wan, Y.Y.1    Flavell, R.A.2
  • 30
    • 2442655250 scopus 로고    scopus 로고
    • Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance
    • Yang Y., Huang C.T., Huang X., and Pardoll D.M. Persistent Toll-like receptor signals are required for reversal of regulatory T cell-mediated CD8 tolerance. Nat Immunol 5 (2004) 508-515
    • (2004) Nat Immunol , vol.5 , pp. 508-515
    • Yang, Y.1    Huang, C.T.2    Huang, X.3    Pardoll, D.M.4
  • 31
    • 34249813714 scopus 로고    scopus 로고
    • Cutting edge: TLR2 directly triggers Th1 effector functions
    • Imanishi T., Hara H., Suzuki S., Suzuki N., Akira A., and Saito T. Cutting edge: TLR2 directly triggers Th1 effector functions. J Immunol 178 (2007) 6715-6719
    • (2007) J Immunol , vol.178 , pp. 6715-6719
    • Imanishi, T.1    Hara, H.2    Suzuki, S.3    Suzuki, N.4    Akira, A.5    Saito, T.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.