메뉴 건너뛰기




Volumn 167, Issue 2, 2008, Pages 358-366

Use of artificial neural networks to determine cognitive impairment and therapeutic effectiveness in Alzheimer's transgenic mice

Author keywords

Alzheimer's disease; Behavioral assessment; Classifier; Discriminant function analysis; Neural networks; Transgenic mice

Indexed keywords

CAFFEINE;

EID: 36849046294     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2007.08.008     Document Type: Article
Times cited : (6)

References (45)
  • 1
    • 0034213103 scopus 로고    scopus 로고
    • Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research
    • Agatonovic-Kustrin S., and Beresford R. Basic concepts of artificial neural network (ANN) modeling and its application in pharmaceutical research. J Pharm Biomed Anal 22 (2000) 717-727
    • (2000) J Pharm Biomed Anal , vol.22 , pp. 717-727
    • Agatonovic-Kustrin, S.1    Beresford, R.2
  • 2
    • 26944479675 scopus 로고    scopus 로고
    • Automatic seizure detection in EEG using logistic regression and artificial neural network
    • Alkan A., Koklukaya E., and Subasi A. Automatic seizure detection in EEG using logistic regression and artificial neural network. J Neurosci Meth 148 (2005) 167-176
    • (2005) J Neurosci Meth , vol.148 , pp. 167-176
    • Alkan, A.1    Koklukaya, E.2    Subasi, A.3
  • 3
    • 0035830686 scopus 로고    scopus 로고
    • Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes
    • Arendash G.W., King D.L., Gordon M.W., Morgan D., Hatcher J.M., Hope C.E., et al. Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes. Brain Res 891 (2001) 42-53
    • (2001) Brain Res , vol.891 , pp. 42-53
    • Arendash, G.W.1    King, D.L.2    Gordon, M.W.3    Morgan, D.4    Hatcher, J.M.5    Hope, C.E.6
  • 4
    • 2442587216 scopus 로고    scopus 로고
    • Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forbrain
    • Arendash G.W., Lewis J., Leighty R.E., McGowan E., Cracchiolo J.R., Hutton M., et al. Multi-metric behavioral comparison of APPsw and P301L models for Alzheimer's disease: linkage of poorer cognitive performance to tau pathology in forbrain. Brain Res 1012 (2004) 29-41
    • (2004) Brain Res , vol.1012 , pp. 29-41
    • Arendash, G.W.1    Lewis, J.2    Leighty, R.E.3    McGowan, E.4    Cracchiolo, J.R.5    Hutton, M.6
  • 5
    • 33750984544 scopus 로고    scopus 로고
    • Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production
    • Arendash G.W., Schleif W., Rezai-Zadeh K., Jackson E.K., Zacharia L.C., Cracchiolo J.R., et al. Caffeine protects Alzheimer's mice against cognitive impairment and reduces brain beta-amyloid production. Neuroscience 142 (2006) 941-952
    • (2006) Neuroscience , vol.142 , pp. 941-952
    • Arendash, G.W.1    Schleif, W.2    Rezai-Zadeh, K.3    Jackson, E.K.4    Zacharia, L.C.5    Cracchiolo, J.R.6
  • 6
    • 0026580903 scopus 로고
    • Application of neural networks to the interpretation of laboratory data in cancer diagnosis
    • Astion M.L., and Wilding P. Application of neural networks to the interpretation of laboratory data in cancer diagnosis. Clin Chem 38 (1992) 34-38
    • (1992) Clin Chem , vol.38 , pp. 34-38
    • Astion, M.L.1    Wilding, P.2
  • 7
    • 0032212323 scopus 로고    scopus 로고
    • Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images
    • Boland M.V., Markey M.K., and Murphy R.F. Automated recognition of patterns characteristic of subcellular structures in fluorescence microscopy images. Cytometry 33 (1998) 366-375
    • (1998) Cytometry , vol.33 , pp. 366-375
    • Boland, M.V.1    Markey, M.K.2    Murphy, R.F.3
  • 8
    • 0028281153 scopus 로고
    • Diagnostic ECG classification based on neural networks
    • Bortolan G., and Willems J.L. Diagnostic ECG classification based on neural networks. J Electrocardiol 26 Suppl. (1993) 75-79
    • (1993) J Electrocardiol , vol.26 , Issue.SUPPL , pp. 75-79
    • Bortolan, G.1    Willems, J.L.2
  • 9
    • 0036317637 scopus 로고    scopus 로고
    • Acoustic identification of female Steller sea lions (Eumetopias jubatus)
    • Campbell G.S., Gisiner R.C., Helweg D.A., and Milette L.L. Acoustic identification of female Steller sea lions (Eumetopias jubatus). J Acoustical Soc Am 111 (2002) 2920-2928
    • (2002) J Acoustical Soc Am , vol.111 , pp. 2920-2928
    • Campbell, G.S.1    Gisiner, R.C.2    Helweg, D.A.3    Milette, L.L.4
  • 12
    • 34548215219 scopus 로고    scopus 로고
    • Enhanced cognitive activity - over and above social or physical activity - is required to protect Alzheimer's mice against cognitive impairment, reduce Aβ deposition, and increase synaptic area
    • Cracchiolo J.R., Mori T., Nazian S., Tan J., Potter H., and Arendash G.W. Enhanced cognitive activity - over and above social or physical activity - is required to protect Alzheimer's mice against cognitive impairment, reduce Aβ deposition, and increase synaptic area. Neurobiol Learn Memory 88 (2007) 277-294
    • (2007) Neurobiol Learn Memory , vol.88 , pp. 277-294
    • Cracchiolo, J.R.1    Mori, T.2    Nazian, S.3    Tan, J.4    Potter, H.5    Arendash, G.W.6
  • 13
    • 0033040026 scopus 로고    scopus 로고
    • Quantifying complex patterns of bioacoustic variation: Use of a neural network to compare killer whale (Orcinus orca) dialects
    • Deecke V.B., Ford J.K., and Spong P. Quantifying complex patterns of bioacoustic variation: Use of a neural network to compare killer whale (Orcinus orca) dialects. J Acoustical Soc Am 105 (1999) 2499-2507
    • (1999) J Acoustical Soc Am , vol.105 , pp. 2499-2507
    • Deecke, V.B.1    Ford, J.K.2    Spong, P.3
  • 14
    • 0037805286 scopus 로고    scopus 로고
    • Detection of subclinical brain electrical activity changes in Huntington's disease using artificial neural networks
    • deTommaso M., DeCarlo F., Difruscolo O., Massafra R., Sciruicchio V., and Bellotti R. Detection of subclinical brain electrical activity changes in Huntington's disease using artificial neural networks. Clin Neurophysiol 114 (2003) 1237-1245
    • (2003) Clin Neurophysiol , vol.114 , pp. 1237-1245
    • deTommaso, M.1    DeCarlo, F.2    Difruscolo, O.3    Massafra, R.4    Sciruicchio, V.5    Bellotti, R.6
  • 15
    • 0042666812 scopus 로고    scopus 로고
    • The relationship between neuropsychological performance and daily functioning in individuals with Alzheimer's disease: ecological validity of neuropsychological tests
    • Farias S.T., Harrell E., Neumann C., and Houtz A. The relationship between neuropsychological performance and daily functioning in individuals with Alzheimer's disease: ecological validity of neuropsychological tests. Arch Clin Neuropsychol 18 (2003) 655-672
    • (2003) Arch Clin Neuropsychol , vol.18 , pp. 655-672
    • Farias, S.T.1    Harrell, E.2    Neumann, C.3    Houtz, A.4
  • 16
    • 0033758332 scopus 로고    scopus 로고
    • Data mining and electroencephalography
    • Flexer A. Data mining and electroencephalography. Stat Meth Med Res 9 (2000) 395-413
    • (2000) Stat Meth Med Res , vol.9 , pp. 395-413
    • Flexer, A.1
  • 17
    • 0037442845 scopus 로고    scopus 로고
    • Review and comparison of methods to study the contribution of variables in artificial neural network models
    • Gevrey M., Dimopoulos I., and Lek S. Review and comparison of methods to study the contribution of variables in artificial neural network models. Ecol Model 160 (2003) 249-264
    • (2003) Ecol Model , vol.160 , pp. 249-264
    • Gevrey, M.1    Dimopoulos, I.2    Lek, S.3
  • 18
    • 0027627472 scopus 로고
    • Classification of drug-induced behaviors using a multi-layer feed-forward neural network
    • Gonzalez L.P., and Arnaldo C.M. Classification of drug-induced behaviors using a multi-layer feed-forward neural network. Comput Methods Programs Biomed 40 (1993) 167-173
    • (1993) Comput Methods Programs Biomed , vol.40 , pp. 167-173
    • Gonzalez, L.P.1    Arnaldo, C.M.2
  • 20
    • 0034137046 scopus 로고    scopus 로고
    • Classifying postures of freely moving rodents with the help of Fourier descriptors and a neural network
    • Heeren D.J., and Cools A.R. Classifying postures of freely moving rodents with the help of Fourier descriptors and a neural network. Behav Res Methods Instrum Comput 32 (2000) 56-62
    • (2000) Behav Res Methods Instrum Comput , vol.32 , pp. 56-62
    • Heeren, D.J.1    Cools, A.R.2
  • 21
    • 0035165228 scopus 로고    scopus 로고
    • Quantitative assessment of vocal development in the zebra finch using self-organizing neural networks
    • Janata P. Quantitative assessment of vocal development in the zebra finch using self-organizing neural networks. J Acoustical Soc Am 110 (2001) 2593-2603
    • (2001) J Acoustical Soc Am , vol.110 , pp. 2593-2603
    • Janata, P.1
  • 22
    • 10044297055 scopus 로고    scopus 로고
    • Lifelong immunization with human β-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging
    • Jensen M.T., Mottin D.M., Cracchiolo J.R., Leighty R.E., and Arendash G.W. Lifelong immunization with human β-amyloid (1-42) protects Alzheimer's transgenic mice against cognitive impairment throughout aging. Neuroscience 130 (2005) 667-684
    • (2005) Neuroscience , vol.130 , pp. 667-684
    • Jensen, M.T.1    Mottin, D.M.2    Cracchiolo, J.R.3    Leighty, R.E.4    Arendash, G.W.5
  • 23
    • 0030870046 scopus 로고    scopus 로고
    • Opening the black box: The relationship between neural networks and linear discriminant functions
    • Kemp R.A., MacAulay C., and Palcic B. Opening the black box: The relationship between neural networks and linear discriminant functions. Anal Cell Pathol 14 (1997) 19-30
    • (1997) Anal Cell Pathol , vol.14 , pp. 19-30
    • Kemp, R.A.1    MacAulay, C.2    Palcic, B.3
  • 24
    • 0031907485 scopus 로고    scopus 로고
    • Recognition of daily life motor activity classes using an artificial neural network
    • Kiani K., Snijders C.J., and Gelsema E.S. Recognition of daily life motor activity classes using an artificial neural network. Arch Phys Med Rehabil 79 (1998) 147-154
    • (1998) Arch Phys Med Rehabil , vol.79 , pp. 147-154
    • Kiani, K.1    Snijders, C.J.2    Gelsema, E.S.3
  • 25
    • 0026680856 scopus 로고
    • Evaluation of a neural-network classifier for PET scans of normal and Alzheimer's disease subjects
    • Kippenhan J.S., Barker W.W., Pascal S., Nagel J., and Duara R. Evaluation of a neural-network classifier for PET scans of normal and Alzheimer's disease subjects. J Nucl Med 33 (1992) 1459-1467
    • (1992) J Nucl Med , vol.33 , pp. 1459-1467
    • Kippenhan, J.S.1    Barker, W.W.2    Pascal, S.3    Nagel, J.4    Duara, R.5
  • 26
    • 3042694083 scopus 로고    scopus 로고
    • Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Abeta deposition
    • Leighty R.E., Nilsson L.N.G., Potter H., Costa D.A., Low M.A., Bales K.R., et al. Use of multimetric statistical analysis to characterize and discriminate between the performance of four Alzheimer's transgenic mouse lines differing in Abeta deposition. Behav Brain Res 153 (2004) 107-121
    • (2004) Behav Brain Res , vol.153 , pp. 107-121
    • Leighty, R.E.1    Nilsson, L.N.G.2    Potter, H.3    Costa, D.A.4    Low, M.A.5    Bales, K.R.6
  • 27
    • 0030428001 scopus 로고    scopus 로고
    • Application of neural networks to modelling nonlinear relationships in ecology
    • Lek S., Delacoste M., Baran P., Dimopoulos I., Lauga J., and Aulagnier S. Application of neural networks to modelling nonlinear relationships in ecology. Ecol Model 90 (1996) 39-52
    • (1996) Ecol Model , vol.90 , pp. 39-52
    • Lek, S.1    Delacoste, M.2    Baran, P.3    Dimopoulos, I.4    Lauga, J.5    Aulagnier, S.6
  • 28
    • 0344604541 scopus 로고    scopus 로고
    • Artificial neural networks as a tool in ecological modelling, an introduction
    • Lek S., and Guegan J.F. Artificial neural networks as a tool in ecological modelling, an introduction. Ecol Model 120 (1999) 65-73
    • (1999) Ecol Model , vol.120 , pp. 65-73
    • Lek, S.1    Guegan, J.F.2
  • 29
    • 0026578134 scopus 로고
    • Introduction of a neuronal network as a tool for diagnostic analysis and classification based on experimental pathologic data
    • Nafe R., and Choritz H. Introduction of a neuronal network as a tool for diagnostic analysis and classification based on experimental pathologic data. Exp Toxicol Pathol 44 (1992) 17-24
    • (1992) Exp Toxicol Pathol , vol.44 , pp. 17-24
    • Nafe, R.1    Choritz, H.2
  • 30
    • 1642528070 scopus 로고    scopus 로고
    • Assessing the cognitive abilities that differentiate patients with Alzheimer's disease from normals: single and multiple factor models
    • Ownby R.L., Loewenstein D.A., Schram L., and Acevedo A. Assessing the cognitive abilities that differentiate patients with Alzheimer's disease from normals: single and multiple factor models. Int J Geriatr Psychiatry 19 (2004) 232-242
    • (2004) Int J Geriatr Psychiatry , vol.19 , pp. 232-242
    • Ownby, R.L.1    Loewenstein, D.A.2    Schram, L.3    Acevedo, A.4
  • 32
    • 0033801419 scopus 로고    scopus 로고
    • Acoustic identification of twelve species of echolocating bat by discriminant function analysis and artificial neural networks
    • Parsons S., and Jones G. Acoustic identification of twelve species of echolocating bat by discriminant function analysis and artificial neural networks. J Exp Biol 203 (2000) 2641-2656
    • (2000) J Exp Biol , vol.203 , pp. 2641-2656
    • Parsons, S.1    Jones, G.2
  • 33
    • 0026332221 scopus 로고
    • Neural networks as a tool for utilizing laboratory information: comparison with linear discriminant analysis and with classification and regression trees
    • Reibnegger G., Weiss G., Werner-Felmayer G., Judmaier G., and Wachter H. Neural networks as a tool for utilizing laboratory information: comparison with linear discriminant analysis and with classification and regression trees. Proc Natl Acad Sci USA 88 (1991) 11426-11430
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 11426-11430
    • Reibnegger, G.1    Weiss, G.2    Werner-Felmayer, G.3    Judmaier, G.4    Wachter, H.5
  • 34
    • 0029986888 scopus 로고    scopus 로고
    • Classification of quantitative EEG data by an artificial neural network: a preliminary study
    • Riquelme L.A., Zanuto B.S., Murer M.G., and Lombardo R.J. Classification of quantitative EEG data by an artificial neural network: a preliminary study. Neuropsychobiology 33 (1996) 106-112
    • (1996) Neuropsychobiology , vol.33 , pp. 106-112
    • Riquelme, L.A.1    Zanuto, B.S.2    Murer, M.G.3    Lombardo, R.J.4
  • 35
    • 0032548892 scopus 로고    scopus 로고
    • Review of neural network applications in sleep research
    • Robert C., Guilpin C., and Limoge A. Review of neural network applications in sleep research. J Neurosci Meth 79 (1998) 187-193
    • (1998) J Neurosci Meth , vol.79 , pp. 187-193
    • Robert, C.1    Guilpin, C.2    Limoge, A.3
  • 36
    • 0032886820 scopus 로고    scopus 로고
    • Use of SHIRPA and discriminant analysis to characterize marked differences in the behavioral phenotype of six inbred mouse strains
    • Rogers D.C., Jones D.N.C., Nelson P.R., Jones C.M., Quilter C.A., Robinson T.L., et al. Use of SHIRPA and discriminant analysis to characterize marked differences in the behavioral phenotype of six inbred mouse strains. Behav Brain Res 105 (1999) 207-217
    • (1999) Behav Brain Res , vol.105 , pp. 207-217
    • Rogers, D.C.1    Jones, D.N.C.2    Nelson, P.R.3    Jones, C.M.4    Quilter, C.A.5    Robinson, T.L.6
  • 38
    • 0022471098 scopus 로고
    • Learning representations by back-propagating errors
    • Rumelhart D.E., Hinton G.E., and Williams R.J. Learning representations by back-propagating errors. Nature 323 (1986) 533-536
    • (1986) Nature , vol.323 , pp. 533-536
    • Rumelhart, D.E.1    Hinton, G.E.2    Williams, R.J.3
  • 40
    • 33644857555 scopus 로고    scopus 로고
    • Neural networks for longitudinal studies in Alzheimer's disease
    • Tandon R., Adak S., and Kaye J.A. Neural networks for longitudinal studies in Alzheimer's disease. Artif Intel Med 36 (2006) 245-255
    • (2006) Artif Intel Med , vol.36 , pp. 245-255
    • Tandon, R.1    Adak, S.2    Kaye, J.A.3
  • 42
    • 33646459451 scopus 로고    scopus 로고
    • A responder analysis of memantine treatment in patients with Alzheimer's disease maintained on donezepil
    • Van Dyck C.H., et al. A responder analysis of memantine treatment in patients with Alzheimer's disease maintained on donezepil. Am J Geriatr Psychiatry 14 (2006) 428-437
    • (2006) Am J Geriatr Psychiatry , vol.14 , pp. 428-437
    • Van Dyck, C.H.1
  • 43
    • 0027670237 scopus 로고
    • Analytic methods to differentiate similar electroencephalographic spectra: Neural network and discriminant analysis
    • Veselis R.A., Reinsel R., and Wronski M. Analytic methods to differentiate similar electroencephalographic spectra: Neural network and discriminant analysis. J Clin Mon 9 (1993) 257-267
    • (1993) J Clin Mon , vol.9 , pp. 257-267
    • Veselis, R.A.1    Reinsel, R.2    Wronski, M.3
  • 44
    • 0030327681 scopus 로고    scopus 로고
    • Understanding neural networks as statistical tools
    • Warner B., and Misra M. Understanding neural networks as statistical tools. Am Stat 50 (1996) 284-293
    • (1996) Am Stat , vol.50 , pp. 284-293
    • Warner, B.1    Misra, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.