Spirofungin A: Stereoselective synthesis and inhibition of isoleucyl-tRNA synthetase

Angewandte Chemie - International Edition

Volumn 46, Issue 46, 2007, Pages 8854-8857

  Marjanovic, Jasmina ^a   Kozmin, Sergey A ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

Metathesis; Natural products; Spiroketals; Stereocontrolled synthesis; tRNA synthetase

Indexed keywords

CHEMICAL EQUATIONS; METATHESIS; POLYKETIDES; SPIROKETALS; STEREOCONTROLLED SYNTHESIS;

CELL PROLIFERATION; RNA; SILICON; STEREOSELECTIVITY; SYNTHESIS (CHEMICAL); TUMORS;

ENZYME INHIBITION;

ANTINEOPLASTIC AGENT; ISOLEUCINE TRANSFER RNA LIGASE; SPIRO COMPOUND; SPIROFUNGIN A; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; DRUG ANTAGONISM; HUMAN; METABOLISM; STREPTOMYCES; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; HUMANS; ISOLEUCINE-TRNA LIGASE; MOLECULAR STRUCTURE; SPIRO COMPOUNDS; STREPTOMYCES;

EID: 36749093348     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200702440     Document Type: Article

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