메뉴 건너뛰기




Volumn 213, Issue 4, 2007, Pages 360-368

The p53-Mdm2 network in progenitor cell expansion during mouse postnatal development

Author keywords

Cell cycle arrest; Cerebellar proliferation; Haematopoiesis; Spermatogenesis

Indexed keywords

CASPASE 3; DOXORUBICIN; PROTEIN MDM2; PROTEIN P53;

EID: 36749082463     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2238     Document Type: Article
Times cited : (49)

References (36)
  • 1
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997;88:323-331.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 3
    • 0035211073 scopus 로고    scopus 로고
    • The p53 functional circuit
    • Jin S, Levine AJ. The p53 functional circuit. J Cell Sci 2001;114:4139-4140.
    • (2001) J Cell Sci , vol.114 , pp. 4139-4140
    • Jin, S.1    Levine, A.J.2
  • 4
    • 18344377030 scopus 로고    scopus 로고
    • The p53 pathway: Positive and negative feedback loops
    • Harris SL, Levine AJ. The p53 pathway: positive and negative feedback loops. Oncogene 2005;24:2899-2908.
    • (2005) Oncogene , vol.24 , pp. 2899-2908
    • Harris, S.L.1    Levine, A.J.2
  • 5
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A, Oren M. Mdm2 promotes the rapid degradation of p53. Nature 1997;387:296-299.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 6
    • 0031583962 scopus 로고    scopus 로고
    • Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53
    • Honda R, Tanaka H, Yasuda H. Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53. FEBS Lett 1997;420:25-27.
    • (1997) FEBS Lett , vol.420 , pp. 25-27
    • Honda, R.1    Tanaka, H.2    Yasuda, H.3
  • 7
  • 8
    • 0027244853 scopus 로고
    • The p53-mdm-2 autoregulatory feedback loop
    • Wu X, Bayle JH, Olson D, Levine AJ. The p53-mdm-2 autoregulatory feedback loop. Genes Dev 1993;7:1126-1132.
    • (1993) Genes Dev , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 9
    • 14644437751 scopus 로고    scopus 로고
    • MDM2 is a central node in the p53 pathway: 12 years and counting
    • Bond GL, Hu W, Levine AJ. MDM2 is a central node in the p53 pathway: 12 years and counting. Curr Cancer Drug Targets 2005;5:3-8.
    • (2005) Curr Cancer Drug Targets , vol.5 , pp. 3-8
    • Bond, G.L.1    Hu, W.2    Levine, A.J.3
  • 10
    • 0028823020 scopus 로고    scopus 로고
    • Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 1995;378:203-206.
    • Montes de Oca Luna R, Wagner DS, Lozano G. Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53. Nature 1995;378:203-206.
  • 11
    • 0028834902 scopus 로고
    • Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53
    • Jones SN, Roe AE, Donehower LA, Bradley A. Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53. Nature 1995;378:206-208.
    • (1995) Nature , vol.378 , pp. 206-208
    • Jones, S.N.1    Roe, A.E.2    Donehower, L.A.3    Bradley, A.4
  • 13
    • 0032549711 scopus 로고    scopus 로고
    • ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways
    • Zhang Y, Xiong Y, Yarbrough WG. ARF promotes MDM2 degradation and stabilizes p53: ARF-INK4a locus deletion impairs both the Rb and p53 tumor suppression pathways. Cell 1998;92:725-734.
    • (1998) Cell , vol.92 , pp. 725-734
    • Zhang, Y.1    Xiong, Y.2    Yarbrough, W.G.3
  • 14
    • 0032549704 scopus 로고    scopus 로고
    • The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
    • Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, et al. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 1998;92:713- 723.
    • (1998) Cell , vol.92 , pp. 713-723
    • Pomerantz, J.1    Schreiber-Agus, N.2    Liegeois, N.J.3    Silverman, A.4    Alland, L.5    Chin, L.6
  • 15
    • 0033959744 scopus 로고    scopus 로고
    • MDM2 - master regulator of the p53 tumor suppressor protein
    • Momand J, Wu HH, Dasgupta G. MDM2 - master regulator of the p53 tumor suppressor protein. Gene 2000;242:15-29.
    • (2000) Gene , vol.242 , pp. 15-29
    • Momand, J.1    Wu, H.H.2    Dasgupta, G.3
  • 16
    • 0032417695 scopus 로고    scopus 로고
    • Over-expression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis
    • Jones SN, Hancock AR, Vogel H, Donehower LA, Bradley A. Over-expression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis. Proc Natl Acad Sci USA 1998;95:15608-15612.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 15608-15612
    • Jones, S.N.1    Hancock, A.R.2    Vogel, H.3    Donehower, L.A.4    Bradley, A.5
  • 17
    • 14444281159 scopus 로고    scopus 로고
    • Lundgren K, Montes de Oca Luna R, McNeill YB, Emerick EP, Spencer B, Barfield CR, et al. Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev 1997;11:714-725.
    • Lundgren K, Montes de Oca Luna R, McNeill YB, Emerick EP, Spencer B, Barfield CR, et al. Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53. Genes Dev 1997;11:714-725.
  • 19
    • 0346455759 scopus 로고    scopus 로고
    • Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice
    • Liu G, Parant JM, Lang G, Chau P, Chavez-Reyes A, EI-Naggar AK, et al. Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice. Nat Genet 2004;36:63-68.
    • (2004) Nat Genet , vol.36 , pp. 63-68
    • Liu, G.1    Parant, J.M.2    Lang, G.3    Chau, P.4    Chavez-Reyes, A.5    EI-Naggar, A.K.6
  • 20
    • 21244473773 scopus 로고    scopus 로고
    • Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform
    • Yaylaoglu MB, Titmus A, Visel A, Alvarez-Bolado G, Thaller C, Eichele G. Comprehensive expression atlas of fibroblast growth factors and their receptors generated by a novel robotic in situ hybridization platform. Dev Dyn 2005;234:371-386.
    • (2005) Dev Dyn , vol.234 , pp. 371-386
    • Yaylaoglu, M.B.1    Titmus, A.2    Visel, A.3    Alvarez-Bolado, G.4    Thaller, C.5    Eichele, G.6
  • 22
    • 27744547091 scopus 로고    scopus 로고
    • Slug antagonizes p53-mediated apoptosis of haematopoietic progenitors by repressing puma
    • Wu WS, Heinrichs S, Xu D, Garrison SP, Zambetti GP, Adams JM, et al. Slug antagonizes p53-mediated apoptosis of haematopoietic progenitors by repressing puma. Cell 2005;123:641-653.
    • (2005) Cell , vol.123 , pp. 641-653
    • Wu, W.S.1    Heinrichs, S.2    Xu, D.3    Garrison, S.P.4    Zambetti, G.P.5    Adams, J.M.6
  • 23
    • 0034074467 scopus 로고    scopus 로고
    • ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes
    • Delia D, Mizutani S, Panigone S, Tagliabue E, Fontaneila E, Asada M, et al. ATM protein and p53-serine 15 phosphorylation in ataxia-telangiectasia (AT) patients and at heterozygotes. Br J Cancer 2000;82:1938-1945.
    • (2000) Br J Cancer , vol.82 , pp. 1938-1945
    • Delia, D.1    Mizutani, S.2    Panigone, S.3    Tagliabue, E.4    Fontaneila, E.5    Asada, M.6
  • 24
    • 0037040205 scopus 로고    scopus 로고
    • ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint
    • Nghiem P, Park PK, Kim Ys YS, Desai BN, Schreiber SL. ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint. J Biol Chem 2002;277:4428-4434.
    • (2002) J Biol Chem , vol.277 , pp. 4428-4434
    • Nghiem, P.1    Park, P.K.2    Kim, Y.Y.3    Desai, B.N.4    Schreiber, S.L.5
  • 25
    • 0032892932 scopus 로고    scopus 로고
    • Activation of p53 by oncogenes
    • Lowe SW. Activation of p53 by oncogenes. Endocr Relat Cancer 1999;6:45-48.
    • (1999) Endocr Relat Cancer , vol.6 , pp. 45-48
    • Lowe, S.W.1
  • 28
    • 28844461213 scopus 로고    scopus 로고
    • Decatenation checkpoint deficiency in stem and progenitor cells
    • Damelin M, Sun YE, Sodja VB, Bestor TH. Decatenation checkpoint deficiency in stem and progenitor cells. Cancer Cell 2005;8:479- 484.
    • (2005) Cancer Cell , vol.8 , pp. 479-484
    • Damelin, M.1    Sun, Y.E.2    Sodja, V.B.3    Bestor, T.H.4
  • 29
    • 0036675901 scopus 로고    scopus 로고
    • The molecular and genetic basis of neurological tumours
    • Zhu Y, Parada LF. The molecular and genetic basis of neurological tumours. Nat Rev Cancer 2002;2:616-626.
    • (2002) Nat Rev Cancer , vol.2 , pp. 616-626
    • Zhu, Y.1    Parada, L.F.2
  • 30
    • 2642541662 scopus 로고    scopus 로고
    • Mouse models of childhood cancer of the nervous system
    • Dyer MA. Mouse models of childhood cancer of the nervous system. J Clin Pathol 2004;57:561-576.
    • (2004) J Clin Pathol , vol.57 , pp. 561-576
    • Dyer, M.A.1
  • 31
    • 0034990241 scopus 로고    scopus 로고
    • What can we learn from leukemia as for the process of lineage commitment in haematopoiesis?
    • Schmidt CA, Przybylski GK. What can we learn from leukemia as for the process of lineage commitment in haematopoiesis? Int Rev Immunol 2001;20:107-115.
    • (2001) Int Rev Immunol , vol.20 , pp. 107-115
    • Schmidt, C.A.1    Przybylski, G.K.2
  • 32
    • 0345269984 scopus 로고    scopus 로고
    • Germline p53 mutations in a cohort with childhood sarcoma: Sex differences in cancer risk
    • Hwang SJ, Lozano G, Amos CI, Strong LC. Germline p53 mutations in a cohort with childhood sarcoma: sex differences in cancer risk. Am J Hum Genet 2003;72:975-983.
    • (2003) Am J Hum Genet , vol.72 , pp. 975-983
    • Hwang, S.J.1    Lozano, G.2    Amos, C.I.3    Strong, L.C.4
  • 33
    • 0037115539 scopus 로고    scopus 로고
    • Tissue-specific induction of p53 targets in vivo
    • Fei P, Bernhard EJ, El-Deiry WS. Tissue-specific induction of p53 targets in vivo. Cancer Res 2002;62:7316-7327.
    • (2002) Cancer Res , vol.62 , pp. 7316-7327
    • Fei, P.1    Bernhard, E.J.2    El-Deiry, W.S.3
  • 34
  • 35
    • 20444369867 scopus 로고    scopus 로고
    • Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells
    • Yang Y, Ludwig RL, Jensen JP, et al. Small molecule inhibitors of HDM2 ubiquitin ligase activity stabilize and activate p53 in cells. Cancer Cell 2005;7:547-559.
    • (2005) Cancer Cell , vol.7 , pp. 547-559
    • Yang, Y.1    Ludwig, R.L.2    Jensen, J.P.3
  • 36
    • 11144315535 scopus 로고    scopus 로고
    • Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors
    • Issaeva N, Bozko P, Enge M, Protopopova M, Verhoef LG, Masucci M. Small molecule RITA binds to p53, blocks p53-HDM-2 interaction and activates p53 function in tumors. Nat Med 2004;10:1321-1328.
    • (2004) Nat Med , vol.10 , pp. 1321-1328
    • Issaeva, N.1    Bozko, P.2    Enge, M.3    Protopopova, M.4    Verhoef, L.G.5    Masucci, M.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.