Brain tau expression and correlation with the H1/H1 tau genotype in frontotemporal lobar degeneration patients

Journal of Neural Transmission

Volumn 114, Issue 12, 2007, Pages 1585-1588

  Llado A ^a   Ezquerra, M ^a   Gaig, C ^a   Sanchez Valle R ^a   Tolosa, E ^a   Molinuevo, J L ^a  

^a HOSPITAL CLÍNIC   (Spain)

Author keywords

Expression; Frontotemporal lobar degeneration; Haplotype; Tau

Indexed keywords

MESSENGER RNA; TAU PROTEIN;

ADULT; AGED; ARTICLE; BRAIN DEGENERATION; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; GENOTYPE; HAPLOTYPE; HETEROZYGOTE; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA SPLICING; TAUOPATHY; TEMPORAL LOBE;

EID: 36749028147     PISSN: 03009564     EISSN: 14351463     Source Type: Journal    
DOI: 10.1007/s00702-007-0786-5     Document Type: Article

References (18)

1. M Baker I Litvan H Houlden J Adamson D Dickson J Perez-Tur J Hardy T Lynch E Bigio M Hutton 1999 Association of an extended haplotype in the tau gene with progressive supranuclear palsy Hum Mol Genet 8 711 715
2. L Buée T Bussière V Buée-Scherrer A Delacourte PR Hof 2000 Tau protein isoforms, phosphorilation and role in neurodegenerative disorders Brain Res Rev 33 95 130
3. TM Caffrey C Joachim S Paracchini MM Esiri R Wade-Martins 2006 Haplotype-specific expression of exon 10 at the human MAPT locus Hum Mol Genet 15 3529 3537
4. NJ Cairns V Zhukareva K Uryu B Zhang E Bigio IR Mackencie M Gearing C Duyckaerts H Yokoo Y Nakazato E Jaros RH Perry VM Lee JQ Trojanowski 2004 Alpha-internexin is present in the pathological inclusions of neuronal intermediate filament inclusion disease Am J Pathol 164 2153 2161
5. CB Chambers JM Lee JC Troncoso S Reich NA Muma 1999 Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease Ann Neurol 46 325 332
6. JW Connell T Rodriguez-Martin GM Gibb NM Kahn AJ Grierson DP Hanger T Revesz PL Lantos BH Anderton JM Gallo 2005 Quantitative analysis of tau isoform transcripts in sporadic tauopathies Brain Res Mol Brain Res 137 104 109
7. M Hutton 2001 Missense and splice site mutations in tau associated with FTDP-17: multiple pathogenic mechanisms Neurology 56 S21 S25
8. Lladó A, Sánchez-Valle R, Rey MJ, Ezquerra M, Tolosa E, Ferrer I, Molinuevo JL (in press) Clinicopathological and genetic correlates of frontotemporal lobar degeneration and corticobasal degeneration. J Neurol XXX
9. GM McKhann MS Albert M Grossman B Miller D Dickson JQ Trojanowski 2001 Report of the work group on frontotemporal dementia and Pick's disease. Clinical and pathological diagnosis of frontotemporal dementia Arch Neurol 58 1803 1809
10. AJ Myers AM Pittman AS Zhao K Rohrer M Kaleem L Marlowe A Lees D Leung IG McKeith RH Perry CM Morris JQ Trojanowski C Clark J Karlawish S Arnold MS Forman V Van Deerlin R de Silva J Hardy 2007 The MAPT H1c risk haplotype is associated with increased expression of tau and especially of 4 repeat containing transcripts Neurobiol Dis 25 561 570
11. M Neumann DM Sampathu LK Kwong AC Truax MC Micsenyi TT Chou J Bruce T Schuck M Grossman CM Clark LF McCluskey BL Miller E Masliah IR Mackenzie H Feldman W Feiden HA Kretzschmar JQ Trojanowski VM Lee 2006 Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis Science 314 130 133
12. P Pastor M Ezquerra JC Perez S Chakraverty J Norton BA Racette D McKeel JS Perlmutter E Tolosa AM Goate 2004 Novel haplotypes in 17q21 are associated with progressive supranuclear palsy Ann Neurol 56 249 258
13. AM Pittman AJ Myers P Abou-Sleiman HC Fung M Kaleem L Marlowe J Duckworth D Leung D Williams L Kilford N Thomas CM Morris D Dickson NW Wood J Hardy AJ Lees R de Silva 2005 Linkage disequilibrium fine mapping and haplotype association analysis of the tau gene in progressive supranuclear palsy and corticobasal degeneration J Med Genet 42 837 846
14. R Rademakers S Melquist M Cruts J Theuns J Del-Favero P Poorkaj M Baker K Sleegers R Crook T De Pooter S Bel Kacem J Adamson D Van den Bossche M Van den Broeck J Gass E Corsmit P De Rijk N Thomas S Engelborghs M Heckman I Litvan J Crook PP De Deyn D Dickson GD Schellenberg C Van Broeckhoven ML Hutton 2005 High-density SNP haplotyping suggests altered regulation of tau gene expression in progressive supranuclear palsy Hum Mol Genet 14 3281 3292
15. J Shi CL Shaw D Du Plessis AM Richardson KL Bailey C Julien C Stopford J Thompson A Varma D Craufurd J Tian S Pickering-Brown D Neary JS Snowden DM Mann 2005 Histopathological changes underlying frontotemporal lobar degeneration with clinicopathological correlation Acta Neuropathol 11 501 512
16. MJ Sobrido BL Miller N Havlioglu V Zhukareva Z Jiang ZS Nasreddine VM Lee TW Chow KC Wilhelmsen JL Cummings JY Wu DH Geschwind 2003 Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia Arch Neurol 60 698 702
17. M Takanashi H Mori K Arima Y Mizuno N Hattori 2002 Expression patterns of tau mRNA isoforms correlate with susceptible lesions in progressive supranuclear palsy and corticobasal degeneration Brain Res Mol Brain Res 104 210 219
18. P Verpillat A Camuzat D Hannequin C Thomas-Anterion M Puel S Belliard B Dubois M Didic BF Michel L Lacomblez O Moreaud F Sellal V Golfier D Campion F Clerget-Darpoux A Brice 2002 Association between the extended tau haplotype and frontotemporal dementia Arch Neurol 59 935 939