Overexpression of four-repeat tau mRNA isoforms in progressive supranuclear palsy but not in Alzheimer's disease

Annals of Neurology

Volumn 46, Issue 3, 1999, Pages 325-332

  Chambers, Christopher B ^a   Lee, John M ^a   Troncoso, Juan C ^b   Reich, Stephen ^b   Muma, Nancy A ^a  

^a LOYOLA UNIVERSITY MEDICAL CENTER   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; CHROMOSOME 17; GENETIC LINKAGE; HUMAN; HUMAN TISSUE; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROGRESSIVE SUPRANUCLEAR PALSY; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RNA ANALYSIS; TISSUE DISTRIBUTION;

AGED; AGED, 80 AND OVER; ALZHEIMER DISEASE; BRAIN; HUMANS; MIDDLE AGED; NEUROFIBRILS; POLYMERASE CHAIN REACTION; REPETITIVE SEQUENCES, NUCLEIC ACID; RNA, MESSENGER; SUPRANUCLEAR PALSY, PROGRESSIVE; TAU PROTEINS;

EID: 0032859650     PISSN: 03645134     EISSN: None     Source Type: Journal    
DOI: 10.1002/1531-8249(199909)46:3<325::AID-ANA8>3.0.CO;2-V     Document Type: Article

References (48)

1. Caceres A, Kosik KS. Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons. Nature 1990;343:461-463
2. Caceres A, Potrebic S, Kosik KS. The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons. J Neurosci 1991;11:1515-1523
3. Cleveland DW, Hwo SY, Kirschner MW. Purification of tau: a microtubule associated protein that induces assembly of microtubules from purified tubulin. J Mol Biol 1977;116:207-225
4. Drubin DG, Kirchner MW. Tau protein function in living cells. J Cell Biol 1986;103:2739-2746
5. Weingarten MD, Lockwood AH, Hwo SY, Kirchner MW. A protein factor essential for microtubule assembly. Proc Natl Acad Sci USA 1975;72:1858-1862
6. Himmler A. Structure of the bovine tau gene: alternatively spliced transcripts generate a protein family. Mol Cell Biol 1989;9:1389-1396
7. Neve RL, Harris P, Kosik KS, et al. Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2. Mol Brain Res 1986;1:271-280
8. Andreadis A, Brown WM, Kosik KS. Structure and novel exons of the human tau gene. Biochemistry 1992;31:10626-10633
9. Goedert M. Tau protein and the neurofibrillary pathology of Alzheimer's disease. Ann NY Acad Sci 1996;777:121-131
10. Lovestone S, Reynolds CH. The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative processes. Neuroscience 1997;78:309-324
11. Chambers CB, Muma NA. Tau mRNA isoforms following sciatic nerve axotomy with and without regeneration. Mol Brain Res 1997;48:115-124
12. Goedert M, Spillantini MG, Jakes R, et al. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 1989;3:519-526
13. Goode BL, Feinstein SC. Identification of a novel microtubule binding and assembly domain in the developmentally regulated inter-repeat region of tau. J Cell Biol 1994;124:769-782
14. Lee G, Neve RL, Kosik KS. The microtubule binding domain of tau protein. Neuron 1989;2:1615-1624
15. Goedert M, Jakes R. Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization. EMBO J 1990;9:4225-4230
16. Litersky JM, Scott CW, Johnson GVW. Phosphorylation, calpain proteolysis and tubulin binding of recombinant human tau isoforms. Brain Res 1993;604:32-40
17. Feany MB, Dickson DW. Neurodegenerative disorders with extensive tau pathology: a comparative study and review. Ann Neurol 1996;40:139-148
18. Khachaturian ZS. Diagnosis of Alzheimer's disease. Arch Neurol 1985;42:1097-1105
19. Hauw J-J, Daniel SE, Dickson D, et al. Preliminary NINDS neuropathological criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy). Neurology 1994;44: 2015-2019
20. Steele JC, Richardson JC, Olszewski J. Progressive supranuclear palsy. Arch Neurol 1964;10:333-359
21. Hyman BT, Trojanowski JQ. Editorial on consensus recommendations for the postmortem diagnosis of Alzheimer disease from the National Institute on Aging and the Reagan Institute Working Group on diagnostic criteria for the neuropathological assessment of Alzheimer disease. J Neuropathol Exp Neurol 1997;56:1095-1097
22. Braak H, Braak E. Neuropathological staging of Alzheimer-related changes. Acta Neuropathol 1991;82:239-259
23. Cervos-Navarro J, Schumacher K. Neurofibrillary pathology in progressive supranuclear palsy (PSP). J Neural Transm Suppl 1994;42:153-164
24. Jellinger K, Bancher C. In: Litvan I, Agid Y , eds. Progressive supranuclear palsy: clinical and research approaches. New York: Oxford University Press, 1992:44-88
25. Arriagada PV, Growdon JH, Hedley-Whyte ET, Hyman BT. Neurofibrillary tangles but not senile plaques parallel duration and severity of Alzheimer's disease. Neurology 1992;42:631-639
26. Bierer LM, Hof PR, Dushyant PP, et al. Neocortical neurofibrillary tangles correlate with dementia severity in Alzheimer's disease. Arch Neurol 1995;52:81-88
27. McKee AC, Kosik KS, Kowall NW. Neuritic pathology and dementia in Alzheimer's disease. Ann Neurol 1991;30:156-165
28. Flament S, Delacourte A, Verny M, et al. Abnormal tau proteins in progressive supranuclear palsy: similarities and differences with the neurofibrillary degeneration of the Alzheimer type. Acta Neuropathol 1991;81:591-596
29. Schmidt ML, Huang R, Martin JA, et al. Neurofibrillary tangles in progressive supranuclear palsy contain the same tau epitopes identified in Alzheimer's disease PHFtau. J Neuropathol Exp Neurol 1996;55:534-539
30. Schmidt ML, Lee VMY, Hurtig H, Trojanowski JQ. Properties of antigenic determinants that distinguish neurofibrillary tangles in progressive supranuclear palsy and Alzheimer's disease. Lab Invest 1988;59:460-466
31. Goedert M, Spillantini MG, Cairns NJ, Crowther RA. Tau proteins of Alzheimer paired helical filaments: abnormal phosphorylation of all six brain isoforms. Neuron 1992;8:159-168
32. Greenberg SG, Davies P, Schein JD, Binder LI. Hydrofluoric acid-treated tau PHF proteins display the same biochemical properties as normal tau. J Biol Chem 1992;267:564-569
33. Ksiezak-Reding H, Shafit-Zagardo B, Yen S-H. Differential expression of exons 10 and 11 in normal tau and tau associated with paired helical filaments. J Neurosci Res 1995;41:583-593
34. Liu W-K, Dickson DW, Yen S-H. Heterogeneity of tau proteins in Alzheimer's disease: evidence for increased expression of an isoform and preferential distribution of a phosphorylated isoform in neurites. Am J Pathol 1993;142:387-394
35. Fratiglioni L. Epidemiology of Alzheimer's disease and current possibilities for prevention. Acta Neurol Scand 1996;165: 33-40
36. Wells D, Hoffman D, Kedes L. Unusual structure, evolutionary conservation of non-coding sequences and numerous pseudogenes characterize the human H3.3 histone multigene family. Nucleic Acid Res 1987;15:2871-2889
37. Goedert M, Spillantini MG, Potier MC, et al. Cloning and sequencing of the cDNA encoding an isoform of microtubule-associated protein tau containing four tandem repeats: differential expression of tau protein mRNAs in human brain. EMBO J 1989;8:393-399
38. Vermersch P, Robitaille Y, Bernier L, et al. Biochemical mapping of neurofibrillary degeneration in a case of progressive supranuclear palsy: evidence for general cortical involvement. Acta Neuropathol 1994;87:572-577
39. Matsumoto R, Nakano I, Arai N, et al. Loss of the dentate nucleus neurons is associated with torpedo formation: a morphometric study in progressive supranuclear palsy and dentatorubro-pallidoluysian atrophy. Acta Neuropathol 1998; 95:149-153
40. Goedert M, Jakes R, Spillantini MG, et al. Assembly of microtubule-associated protein tau into Alzheimer-like filaments induced by sulphated glycosaminoglycans. Nature 1996;383: 550-553
41. Andreadis A, Wagner BK, Broderick JA, Kosik KS. A tau promoter region without neuronal specificity. J Neurochem 1996; 66:2257-2263
42. Sadot E, Heicklen-Klein A, Barg J, et al. Identification of a tau promoter region mediating tissue-specific-regulated expression in PC12 cells. J Mol Biol 1996;256:805-812
43. Esclaire F, Lesort M, Blanchard C, Hugon J. Glutamate toxicity enhances tau gene expression in neuronal cultures. J Neurosci Res 1997;49:309-318
44. Aniello F, Couchie D, Bridoux AM, et al. Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone. Proc Natl Acad Sci USA 1991;88:4035-4039
45. Conrad C, Andreadis A, Trojanowski JQ, et al. Genetic evidence for the involvement of tau in progressive supranuclear palsy. Ann Neurol 1997;41:277-281
46. Hutton M, Lendon CL, Rizzu P, et al. Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17. Nature 1998;393:702-705
47. Poorkaj P, Bird TD, Wijsman E, et al. Tau is a candidate gene for chromosome 17 frontotemporal dementia. Ann Neurol 1998;43:815-824
48. Spillantini MG, Goedert M, Crowther RA, et al. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proc Natl Acad Sci USA 1997;94:4113-4118