Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa

Matrix Biology

Volumn 26, Issue 8, 2007, Pages 652-658

  Petrou, Petros ^a   Pavlakis, Evangelos ^a   Dalezios, Yannis ^a,b   Chalepakis, Georges ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b INSTITUTE OF COMPUTER SCIENCE   (Greece)

Author keywords

Basement membrane; Fras1; Fraser syndrome; Frem1; Frem2; Frem3; Mouse bleb mutants

Indexed keywords

PROTEIN FRAS1; PROTEIN FREM1; PROTEIN FREM2; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BASEMENT MEMBRANE; COMPLEX FORMATION; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYO; EPITHELIUM CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANIMALS; BASEMENT MEMBRANE; EPITHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; MICE; MICE, KNOCKOUT; MICROSCOPY, ELECTRON, TRANSMISSION; MICROSCOPY, IMMUNOELECTRON; MUTATION; PROTEIN BINDING; SKIN;

EID: 36549080131     PISSN: 0945053X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.matbio.2007.05.008     Document Type: Article

References (18)

1. Chiotaki R., Petrou P., Giakoumaki E., Pavlakis E., Sitaru C., and Chalepakis G. Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr. Patterns 7 (2007) 381-388
2. Dalezios Y., Lujan R., Shigemoto R., Roberts J.D., and Somogyi P. Enrichment of mGluR7a in the presynaptic active zones of GABAergic and non-GABAergic terminals on interneurons in the rat somatosensory cortex. Cereb. Cortex 12 (2002) 961-974
3. Horiguchi Y., Fine J.-D., Ljubimov A.V., Yamasaki H., and Couchman J.R. Entactin: ultrastructural localization of an ubiquitous basement membrane glycoprotein in mouse skin. Arch. Dermatol. Res. 281 (1989) 427-432
4. Jadeja S., Smyth I., Pitera J.E., Taylor M.S., van Haelst M., Bentley E., McGregor L., Hopkins J., Chalepakis G., Philip N., Aytes A.P., Watt F.M., Darling S.M., Jackson I., Woolf A.S., and Scambler P.J. Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat. Genet. 37 (2005) 520-525
5. Kalluri R. Basement membranes: structure, assembly and role in tumour angiogenesis. Nat. Rev., Cancer 3 (2003) 422-433
6. Kiyozumi D., Osada A., Sugimoto N., Weber C.N., Ono Y., Imai T., Okada A., and Sekiguchi K. Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle. Exp. Cell Res. 306 (2005) 9-23
7. Kiyozumi D., Sugimoto N., and Sekiguchi K. Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1 and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc. Natl. Acad. Sci. U. S. A. 103 (2006) 11981-11986
8. Matsunaga T. Epidermal basement membrane: its molecular organization and blistering disorders. Connect. Tissue Res. 47 (2006) 55-56
9. McGregor L., Makela V., Darling S.M., Vrontou S., Chalepakis G., Roberts C., Smart N., Rutland P., Prescott N., Hopkins J., Bentley E., Shaw A., Roberts E., Mueller R., Jadeja S., Philip N., Nelson J., Francannet C., Perez-Aytes A., Megarbane A., Kerr B., Wainwright B., Woolf A.S., Winter R.M., and Scambler P.J. Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein. Nat. Genet. 34 (2003) 203-208
10. Petrou P., Pavlakis E., Dalezios Y., Galanopoulos V.K., and Chalepakis G. Basement membrane distortions impair lung lobation and capillary organization in the mouse model for Fraser syndrome. J. Biol. Chem. 280 (2005) 10350-10356
11. Petrou P., Chiotaki R., Dalezios Y., and Chalepakis G. Overlapping and divergent localization of Fras1 and Frem1 and its functional implications during embryonic development. Exp. Cell Res. 313 (2007) 910-920
12. Relan N.K., and Schuger L. Basement membranes in development. Pediatr. Dev. Pathol. 2 (1999) 103-118
13. Smyth I., and Scambler P. The genetics of Fraser syndrome and the blebs mouse mutants. Hum. Mol. Genet. 14 2 (2005) R269-R274
14. Smyth I., Du X., Taylor M.S., Justice M.J., Beutler B., and Jackson I.J. The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic dermis. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 13560-13565
15. Takamiya K., Kostourou V., Adams S., Jadeja S., Chalepakis G., Scambler P.J., Huganir R.L., and Adams R.H. A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1. Nat. Genet. 36 (2004) 172-177
16. Timmer J.R., Mak T.W., Manova K., Anderson K.V., and Niswander L. Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene. Proc. Natl. Acad. Sci. U. S. A. 102 (2005) 11746-11750
17. Vrontou S., Petrou P., Meyer B.I., Galanopoulos V.K., Imai K., Yanagi M., Chowdhury K., Scambler P.J., and Chalepakis G. Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat. Genet. 34 (2003) 209-214
18. Yang H., Wanner I.B., Roper S.D., and Chaudhari N. An optimized method for in situ hybridization with signal amplification that allows the detection of rare mRNAs. J. Histochem. Cytochem. 47 (1999) 431-445