Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development

Gene Expression Patterns

Volumn 7, Issue 4, 2007, Pages 381-388

  Chiotaki, Rena ^a   Petrou, Petros ^a   Giakoumaki, Elsa ^a   Pavlakis, Evangelos ^a   Sitaru, Cassian ^b   Chalepakis, Georges ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Basement membrane; Bleb mutants; Collagen VII; Development; Fras1; Fraser syndrome; Frem1; Frem2; Frem3; Immunohistochemistry; Mouse embryo

Indexed keywords

COLLAGEN TYPE 7; FRAS1 PROTEIN; FREM PROTEIN; FREM1 PROTEIN; FREM2 PROTEIN; FREM3 PROTEIN; PROTEIN SUBUNIT; SCLEROPROTEIN; UNCLASSIFIED DRUG;

ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BASEMENT MEMBRANE; BLISTER; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; EPIDERMIS; EPIDERMOLYSIS BULLOSA; EYELID; FRASER SYNDROME; GASTROINTESTINAL TRACT; IMMUNOFLUORESCENCE; KIDNEY EPITHELIUM; LIMB; LUNG ALVEOLUS EPITHELIUM; MOUSE; MULTIGENE FAMILY; MUTATIONAL ANALYSIS; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STRUCTURE;

ANIMALS; BASEMENT MEMBRANE; COLLAGEN TYPE VII; EMBRYO; EMBRYONIC DEVELOPMENT; EPITHELIUM; EXTRACELLULAR MATRIX PROTEINS; MICE; MICE, MUTANT STRAINS; PHENOTYPE; SKIN;

MUS;

EID: 33846608655     PISSN: 1567133X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.modgep.2006.12.001     Document Type: Article

References (20)

1. Bruckner-Tuderman L., Hopfner B., and Hammami-Hauasli N. Biology of anchoring fibrils: lessons from dystrophic epidermolysis bullosa. Matrix Biol. 18 (1999) 43-54
2. Clos J., and Brandau S. pJC20 and pJC40 - two high-copy-number vectors for T7 RNA polymerase-dependent expression of recombinant genes in Escherichia coli. Protein Expr. Purif. 5 (1994) 133-137
3. Darling S., and Gossler A. A mouse model for Fraser syndrome?. Clin. Dysmorphol. 3 (1994) 91-95
4. Harris M.J., and McLeod M.J. Eyelid growth and fusion in fetal mice: a scanning electron microscope study. Anat. Embryol. 164 (1982) 207-220
5. Heinonen S., Mannikko M., Klement J.F., Whitaker-Menezes D., Murphy G.F., and Uitto J. Targeted inactivation of the type VII collagen gene (Col7a1) in mice results in severe blistering phenotype: a model for recessive dystrophic epidermolysis bullosa. J. Cell Sci. 112 (1999) 3641-3648
6. Jadeja S., Smyth I., Pitera J.E., Taylor M.S., van Haelst M., Bentley E., McGregor L., Hopkins J., Chalepakis G., Philip N., Perez Aytes A., Watt F.M., Darling S.M., Jackson I., Woolf A.S., and Scambler P.J. Identification of a new gene mutated in Fraser syndrome and mouse myelencephalic blebs. Nat. Genet. 37 (2005) 520-525
7. Kiyozumi D., Osada A., Sugimoto N., Weber C.N., Ono Y., Imai T., Okada A., and Sekiguchi K. Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle. Exp. Cell Res. 306 (2005) 9-23
8. Kiyozumi D., Sugimoto N., and Sekiguchi K. Breakdown of the reciprocal stabilization of QBRICK/Frem1, Fras1, and Frem2 at the basement membrane provokes Fraser syndrome-like defects. Proc. Natl. Acad. Sci. 103 (2006) 11981-11986
9. Maconnachie E.A. A study of digit fusion in the mouse embryo. J. Embryol. Exp. Morphol. 49 (1979) 259-276
10. McGregor L., Makela V., Darling S.M., Vrontou S., Chalepakis G., Roberts C., Smart N., Rutland P., Prescott N., Hopkins J., Bentley E., Shaw A., Roberts E., Mueller R., Jadeja S., Philip N., Nelson J., Francannet C., Perez-Aytes A., Megarbane A., Kerr B., Wainwright B., Woolf A.S., Winter R.M., and Scambler P.J. Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein. Nat. Genet. 34 (2003) 203-208
11. Petrou P., Pavlakis E., Dalezios Y., Galanopoulos V.K., and Chalepakis G. Basement membrane distortions impair lung lobation and capillary organization in the mouse model for Fraser syndrome. J. Biol. Chem. 280 (2005) 10350-10356
12. Sakai L.Y., Keene D.R., Morris N.P., and Burgeson R.E. Type VII Collagen is a major structural component of anchoring fibrils. J. Cell Biol. 103 (1986) 1577-1586
13. Sitaru C., Mihai S., Otto C., Chiriac M.T., Hausser I., Dotterweich B., Saito H., Rose C., Ishiko A., and Zillikens D. Induction of dermal-epidermal separation in mice by passive transfer of antibodies specific to type VII collagen. J. Clin. Invest. 115 (2005) 870-878
14. Slavotinek A.M., and Tifft C.J. Fraser syndrome and cryptophthalmos: Review of the diagnostic criteria and evidence for phenotypic modules in complex malformation syndromes. J. Med. Genet. 39 (2002) 623-633
15. Smyth I., Du X., Taylor M.S., Justice M.J., Beutler B., and Jackson I.J. The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc. Natl. Acad. Sci. 101 (2004) 13560-13565
16. Smyth I., and Scambler P.J. The genetics of Fraser syndrome and the blebs mouse mutants. Hum. Mol. Genet. 2 (2005) 269-274
17. Takamiya K., Kostourou V., Adams S., Jadeja S., Chalepakis G., Scambler P.J., Huganir R.L., and Adams R.H. A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1. Nat. Genet. 36 (2004) 172-177
18. Timmer J.R., Mak T.W., Manova K., Anderson K.V., and Niswander L. Tissue morphogenesis and vascular stability require the Frem2 protein, product of the mouse myelencephalic blebs gene. Proc. Natl. Acad. Sci. 102 (2005) 11746-11750
19. Vrontou S., Petrou P., Meyer B.I., Galanopoulos V.K., Imai K., Yanagi M., Chodhury K., Scambler P.J., and Chalepakis G. Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat. Genet. 34 (2003) 209-214
20. Winter R.M. Fraser syndrome and mouse 'bleb' mutants. Clin. Genet. 37 (1990) 494-495