Interactions between mycoplasma lipid-associated membrane proteins and the host cells

Journal of Zhejiang University: Science B

Volumn 7, Issue 5, 2006, Pages 342-350

  You, Xiao xing ^a   Zeng, Yan hua ^a   Wu, Yi mou ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

Author keywords

Immunomodulin; Lipid associated membrane proteins (LAMPs); Mycoplasma; R37; Toll like receptor (TLR)

Indexed keywords

LIPID; MEMBRANE PROTEIN;

ANIMAL; BACTERIAL INFECTION; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MYCOPLASMA; PATHOLOGY; PHYSIOLOGY; PROTEIN BINDING; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; HUMANS; LIPIDS; MEMBRANE PROTEINS; MYCOPLASMA; MYCOPLASMA INFECTIONS; PROTEIN BINDING; SIGNAL TRANSDUCTION;

EID: 36549075846     PISSN: 16731581     EISSN: 18621783     Source Type: Journal    
DOI: 10.1631/jzus.2006.B0342     Document Type: Review

References (38)

1. Akira, S., Takeda, K., Kaisho, T., 2001. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat. Immunol., 2(8):675–680. [doi:10.1038/90609] DOI: 10.1038/90609
2. Baseman, J.B., Lange, M., Criseimagna, N.L., Giron, J.A., Thomas, C.A., 1995. Interplay between mycoplasmas and host target cells. Microb. Pathog., 19(2):105–116. [doi:10.1006/mpat.1995.0050] DOI: 10.1006/mpat.1995.0050
3. Buwitt-Beckmann, U., Heine, H., Wiesmuller, K.H., Jung, G., Brock, R., Akira, S., Ulmer, A.J., 2005. Toll-like receptor 6-independent signaling by diacylated lipopeptides. Eur. J. Immunol., 35(1):282–289. [doi:10.1002/eji.200424955] DOI: 10.1002/eji.200424955
4. Chambaud, I., Wroblewski, H., Blanchard, A., 1999. Interactions between mycoplasma lipoproteins and the host immune system. Trends Microbiol., 7(12):493–499. [doi:10.1016/S0966-842X(99)01641-8] DOI: 10.1016/S0966-842X(99)01641-8
5. Davis, K.L., Wise, K.S., 2002. Site-specific proteolysis of the MALP-404 lipoprotein determines the release of a soluble selective lipoprotein-associated motif-containing fragment and alteration of the surface phenotype of Mycoplasma fermentans. Infect. Immun., 70(3):1129–1135. [doi:10.1128/IAI.70.3.1129-1135.2002] DOI: 10.1128/IAI.70.3.1129-1135.2002
6. Feng, S.H., Tsai, S., Rodriguez, J., Lo, S.C., 1999. Mycoplasmal infections prevent apoptosis and induce malignant transformation of interleukin-2-dependent 32D hematopoietic cells. Mol. Cell Biol., 19(12):7995–8002.
7. Fujita, M., Into, T., Yasuda, M., Okusawa, T., Hamahira, S., Kuroki, Y., Eto, A., Nisizawa, T., Morita, M., Shibata, K.I., 2003. Involvement of leucine resides at position 107, 112, and 115 in a leucine-rich repeat motif of human Toll-like receptor 2 in the recognition of diacylated lipoprotein and lipopeptide and Staphylococcus aureus peptidoglycans. J. Immunol., 171(7):3675–3683.
8. Garcia, J., Lemercier, B., Roman-Roman, S., Rawadi, G., 1998. A Mycoplasma fermentans-derived synthetic lipopeptide induces AP-1 and NF-κB activity and cytokine secretion in macrophages via the activation of mitogen-activated protein kinase pathways. J. Biol. Chem., 273(51):34391–34398. [doi:10.1074/jbc.273.51.34391] DOI: 10.1074/jbc.273.51.34391
9. Hall, R.E., Agarwal, S., Kestler, D.P., 2000. Induction of leukemia cell differentiation and apoptosis by recombinant P48, a modulin derived from Mycoplasma fermentans. Biochem. Biophys. Res. Commun., 269(1):284–289. [doi:10.1006/bbrc.2000.2282] DOI: 10.1006/bbrc.2000.2282
10. Henderson, B., Poole, S., Wleson, M., 1996. Bacterial modulins: a novel class of virulence factors which cause host tissue pathology by inducing cytokine synthesis. Microbiol. Rev., 60(2):316–341.
11. Horino, A., Sasaki, Y., Sasaki, T., Kenri, T., 2003. Multiple promoter inversions generate surface antigenic variation in Mycoplasma penetrans. J. Bacteriol., 185(1):231–242. [doi:10.1128/JB.185.1.231-242.2003] DOI: 10.1128/JB.185.1.231-242.2003
12. Into, T., Nodasaka, Y., Hasebe, A., Okuzawa, T., Nakamura, J., Ohata, N., Shibata, K., 2002a. Mycoplasmal lipoproteins induce Toll-like receptor 2 and caspases-mediated cell death in lymphocytes and monocytes. Microbiol. Immunol., 46(4):265–276.
13. Into, T., Okada, K., Inoue, N., Yasuda, M., Shibata, K., 2002b. Extracellular ATP regulates cell death of lymphocytes and monocytes induced by membrane-bound lipoproteins of Mycoplasma fermentans and Mycoplasma salivarium. Microbiol. Immunol., 46(10):667–675.
14. Into, T., Kiura, K., Yasuda, M., Kataoka, H., Inoue, N., Hasebe, A., Takeda, K., Akira, S., Shibata, K., 2004. Stimulation of human Toll-like receptor (TLR) 2 and TLR6 with membrane lipoproteins of Mycoplasma fermentans induces apoptotic cell death after NF-kappa B activation. Cell. Microbiol., 6(2):187–199. [doi:10.1046/j.1462-5822.2003.00356.x] DOI: 10.1046/j.1462-5822.2003.00356.x
15. Iyama, K., Zhang, S., Lo, S.C., 2001. Effects of mycoplasmal LAMPs on receptor responses to steroid hormones in mammalian cells. Curr. Microbiol., 43(3):163–169. [doi:10.1007/s002840010281] DOI: 10.1007/s002840010281
16. Mühlradt, P.F., Schade, U., 1991. MDHM, a macrophage-stimulatory product of Mycoplasma fermentans, leads to in vitro interleukin-1 (IL-1), IL-6, tumor necrosis factor, and prostaglandin production and is pyrogenic in rabbits. Infect. Immun., 59(11):3969–3974.
17. Mühlradt, P.F., Frisch, M., 1994. Purification and partial biochemical characterization of a Mycoplasma fermentans-derived substance that activates macrophages to release nitric oxide, tumor necrosis factor, and interleukin-6. Infect. Immun., 62(9):3801–3807.
18. Mühlradt, P.F., Kiess, M., Meyer, H., Sussmuth, R., Jung, G., 1997. Isolation, structure elucidation, and synthesis of a macrophage stimulatory lipopeptide from Mycoplasma fermentans acting at picomolar concentration. J. Exp. Med., 185(11):1951–1958. [doi:10.1084/jem.185.11.1951] DOI: 10.1084/jem.185.11.1951
19. Rawadi, G., 2000. Mycoplasma fermentans interaction with monocytes/macrophages: molecular basis. Microbes Infect., 2(8):955–964. [doi:10.1016/S1286-4579(00)00395-6] DOI: 10.1016/S1286-4579(00)00395-6
20. Rawadi, G., Roman-Roman, S., Castedo, M., Dutilleul, V., Susin, S., Marchetti, P., Geuskens, M., Kroemer, G., 1996. Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential. J. Immunol., 156(2):670–678.
21. Rawadi, G., Garcia, J., Lemercier, B., Roman-Roman, S., 1999. Signal transduction pathways involved in the activation of NF-kappa B, AP-1, and c-fos by Mycoplasma fermentans membrane lipoproteins in macrophages. J. Immunol., 162(4):2193–2203.
22. Razin, S., Yogev, D., Naot, Y., 1998. Molecular biology and pathogenicity of mycoplasmas. Microbiol. Rev., 62(4):1094–1156.
23. Rock, F.L., Hardiman, G., Timans, J.C., Kastelein, R.A., Bazan, J.F., 1998. A family of human receptors structurally related to Drosophila Toll. Proc. Natl. Acad. Sci. USA, 95(2):588–593. DOI: 10.1073/pnas.95.2.588
24. Romero, F., Moreno, E., Ruiz-Bravo, A., Jimenez-Valera, M., 2004. In vivo immunomodulation by Mycoplasma fermentans membrane lipoprotein. Curr. Microbiol., 48(3):237–239. [doi:10.1007/s00284-003-4134-1] DOI: 10.1007/s00284-003-4134-1
25. Roske, K., Blanchard, A., Chambaud, I., Citti, C., Helbig, J.H., Prevost, M.C., Rosengarten, R., Jacobs, E., 2001. Phase variation among major surface antigens of Mycoplasma penetrans. Infect. Immun., 69(12):7642–7651. [doi:10.1128/IAI.69.12.7642-7651.2001] DOI: 10.1128/IAI.69.12.7642-7651.2001
26. Rottem, S., 2003. Interaction of mycoplasmas with host cells. Physiol. Rev., 83(2):417–432.
27. Schroder, N.U., Heine, H., Alexander, C., Manukyan, M., Eckert, J., Hamann, L., Gobel, U.B., Schumann, R.R., 2004. Lipopolysaccharide binding protein binds to triacylated and diacylated lipopeptides and mediates innate immune responses. J. Immunol., 173(4):2683–2691.
28. Seya, T., Matsumoto, M., 2002. A lipoprotein family from Mycoplasma fermentans confers host immune activation through Toll-like receptor 2. Int. J. Biochem. Cell Biol., 34(8):901–906. [doi:10.1016/S1357-2725(01)00164-9] DOI: 10.1016/S1357-2725(01)00164-9
29. Shibata, K., Hasebe, A., Into, T., Yamada, M., Watanabe, T., 2000. The N-terminal lipopeptide of a 44-kDa membrane-bound lipoprotein of Mycoplasma salivarium is responsible for the expression of intercellular adhesion molecule-1 on the cell surface of normal human gingival fibroblasts. J. Immunol., 165(11):6538–6544.
30. Shimizu, T., Kida, Y., Kuwano, K., 2004. Lipid-associated membrane proteins of Mycoplasma fermentans and Mycoplasma penetrans activate human immunodeficiency virus long-terminal repeats through Toll-like receptors. Immunology, 113(1):121–129. [doi:10.1111/j.1365-2567.2004.01937.x] DOI: 10.1111/j.1365-2567.2004.01937.x
31. Shimizu, T., Kida, Y., Kuwano, K., 2005. A dipalmitoylated lipoprotein from Mycoplasma pneumoniae activates NF-κB through TLR1, TLR2, and TLR6. J. Immunol., 175(7):4641–4646.
32. Simmons, W.L., Dybvig, K., 2003. The Vsa proteins modulate susceptibility of Mycoplasma pulmonis to complement killing, hemadsorption, and adherence to polystyrene. Infect. Immun., 71(10):5733–5738. [doi:10.1128/IAI.71.10.5733-5738.2003] DOI: 10.1128/IAI.71.10.5733-5738.2003
33. Takeda, K., Akira, S., 2001. Roles of Toll-like receptors in innate immune responses. Genes Cells, 6(9):733–742. [doi:10.1046/j.1365-2443.2001.00458.x] DOI: 10.1046/j.1365-2443.2001.00458.x
34. Takeuchi, O., Kaufmann, A., Grote, K., Kawai, T., Hoshino, K., Morr, M., Muhlradt, P.F., Akira, S., 2000. Cutting edge: preferentially the R-stereoisomer of the Mycoplasmal lipopeptide macrophage-activating lipopeptide-2 activates immune cells through a Toll-Like receptor 2-and MyD88-dependent signaling pathway. J. Immunol., 164(2):554–557.
35. Takeuchi, O., Sato, S., Horiuchi, T., Hoshino, K., Takeda, K., Dong, Z., Modlin, R.L., Akira, S., 2002. Cutting edge: role of Toll-like receptor 1 in mediating immune response to microbial lipoproteins. J. Immunol., 169(1):10–14.
36. Tu, A.H., Clapper, B., Schoeb, T.R., Elgavish, A., Zhang, J., Liu, L., Yu, H., Dybvig, K., 2005. Association of a major protein antigen of Mycoplasma arthritidis with virulence. Infect. Immun., 73(1):245–249. [doi:10.1128/IAI.73.1.245-249.2005] DOI: 10.1128/IAI.73.1.245-249.2005
37. Zeng, Y.H., Wu, Y.M., Zhang, W.B., Yu, M.J., Zhu, C.M., Tan, L.Z., 2004. Activation of nuclear factor kappaB and induction of inducible nitric oxide synthase by lipid-associated membrane proteins isolated from Mycoplasma penetrans. Chin. Med. J. (Engl.), 117(7):997–1001.
38. Zhang, Q., Wise, K.S., 2001. Coupled phase-variable expression and epitope masking of selective surface lipoproteins increase surface phenotypic diversity in Mycoplasma hominis. Infect. Immun., 69(8):5177–5181. [doi:10.1128/IAI.69.8.5177-5181.2001] DOI: 10.1128/IAI.69.8.5177-5181.2001