E-box regulation of gonadotropin-releasing hormone (GnRH) receptor expression in immortalized gonadotrope cells

Molecular and Cellular Endocrinology

Volumn 278, Issue 1-2, 2007, Pages 36-43

  Resuehr, D ^a   Wildemann, U ^b   Sikes, H ^a   Olcese, J ^a  

^a FLORIDA STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b University of Medical School Hamburg Eppendorf   (Germany)

Author keywords

Clock; E box; Gonadotropin releasing hormone receptor; Period; Pituitary

Indexed keywords

GONADORELIN RECEPTOR; LUCIFERASE; PER1 PROTEIN; PROTEIN BMAL1; TRANSCRIPTION FACTOR CLOCK;

ANIMAL CELL; ARTICLE; CELL IMMORTALIZATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA FLANKING REGION; E BOX ELEMENT; GENE SEQUENCE; GENETIC TRANSCRIPTION; GONADOTROPIN SECRETING CELL; HYPOPHYSIS; IMMUNOREACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA INTERFERENCE;

EID: 36549062432     PISSN: 03037207     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mce.2007.08.008     Document Type: Article

References (50)

1. Abe M., Herzog E.D., Yamazaki S., Straume M., Tei H., Sakaki Y., Menaker M., and Block G.D. Circadian rhythms in isolated brain regions. J. Neurosci. 22 (2002) 350-356
2. Alarid E.T., Holley S., Hayakawa M., and Mellon P.L. Discrete stages of anterior pituitary differentiation recapitulated in immortalized cell lines. Mol. Cell Endocrinol. 140 (1998) 25-30
3. Bedecarrats G.Y., and Kaiser U.B. Differential regulation of gonadotropin subunit gene promoter activity by pulsatile gonadotropin-releasing hormone (GnRH) in perifused L beta T2 cells: role of GnRH receptor concentration. Endocrinology 144 (2003) 1802-1811
4. Chappell P.E., White R.S., and Mellon P.L. Circadian gene expression regulates pulsatile gonadotropin-releasing hormone (GnRH) secretory patterns in the hypothalamic GnRH-secreting GT1-7 cell line. J. Neurosci. 23 (2003) 11202-11213
5. Duval D.L., Farris A.R., Quirk C.C., Nett T.M., Hamernik D.L., and Clay C.M. Responsiveness of the ovine gonadotropin-releasing hormone receptor gene to estradiol and gonadotropin-releasing hormone is not detectable in vitro but is revealed in transgenic mice. Endocrinology 141 (2000) 1001-1010
6. Everett J.W., and Sawyer C.H. A 24-hour periodicity in the "LH-release apparatus" of female rats, disclosed by barbiturate sedation. Endocrinology 47 (1950) 198-218
7. Fernandez-Vazquez G., Kaiser U.B., Albarracin C.T., and Chin W.W. Transcriptional activation of the gonadotropin-releasing hormone receptor gene by activin A. Mol. Endocrinol. 10 (1996) 356-366
8. Funabashi T., Shinohara K., Mitsushima D., and Kimura F. Gonadotropin-releasing hormone exhibits circadian rhythm in phase with arginine-vasopressin in co-cultures of the female rat preoptic area and suprachiasmatic nucleus. J. Neuroendocrinol. 12 (2000) 521-528
9. Garrel G., Lozach A., Bachir L.K., Laverriere J.N., and Counis R. Pituitary adenylate cyclase-activating polypeptide stimulates nitric-oxide synthase type I expression and potentiates the cGMP response to gonadotropin-releasing hormone of rat pituitary gonadotrophs. J. Biol. Chem. 277 (2002) 46391-46401
10. Gregg D.W., Schwall R.H., and Nett T.M. Regulation of gonadotropin secretion and number of gonadotropin-releasing hormone receptors by inhibin, activin-A, and estradiol. Biol. Reprod. 44 (1991) 725-732
11. Hall J.C. Are cycling gene products as internal zeitgebers no longer the zeitgeist of chronobiology?. Neuron 17 (1996) 799-802
12. Hastings M.H., Reddy A.B., and Maywood E.S. A clockwork web: circadian timing in brain and periphery, in health and disease. Nat. Rev. Neurosci. 4 (2003) 649-661
13. Herzog E.D., Grace M.S., Harrer C., Williamson J., Shinohara K., and Block G.D. The role of Clock in the developmental expression of neuropeptides in the suprachiasmatic nucleus. J. Comp. Neurol. 424 (2000) 86-98
14. Jin X., Shearman L.P., Weaver D.R., Zylka M.J., de Vries G.J., and Reppert S.M. A molecular mechanism regulating rhythmic output from the suprachiasmatic circadian clock. Cell 96 (1999) 57-68
15. Johnston J.D., Cagampang F.R., Stirland J.A., Carr A.J., White M.R., Davis J.R., and Loudon A.S. Evidence for an endogenous per1- and ICER-independent seasonal timer in the hamster pituitary gland. FASEB J. 17 (2003) 810-815
16. Kaiser U.B., Jakubowiak A., Steinberger A., and Chin W.W. Regulation of rat pituitary gonadotropin-releasing hormone receptor mRNA levels in vivo and in vitro. Endocrinology 133 (1993) 931-934
17. Kakar S.S., Malik M.T., and Winters S.J. Gonadotropin-releasing hormone receptor: cloning, expression and transcriptional regulation. Prog. Brain Res. 141 (2002) 129-147
18. Kakar S.S., Winters S.J., Zacharias W., Miller D.M., and Flynn S. Identification of distinct gene expression profiles associated with treatment of LbetaT2 cells with gonadotropin-releasing hormone agonist using microarray analysis. Gene 308 (2003) 67-77
19. Kennaway D.J., Boden M.J., and Voultsios A. Reproductive performance in female Clock(Delta19) mutant mice. Reprod. Fertil. Dev. 16 (2005) 801-810
20. Leclerc G.M., and Boockfor F.R. Pulses of prolactin promoter activity depend on a noncanonical E-box that can bind the circadian proteins CLOCK and BMAL1. Endocrinology 146 (2005) 2782-2790
21. Lee C., Etchegaray J.P., Cagampang F.R., Loudon A.S., and Reppert S.M. Posttranslational mechanisms regulate the mammalian circadian clock. Cell 107 (2001) 855-867
22. Legan S.J., Coon G.A., and Karsch F.J. Role of estrogen as initiator of daily LH surges in the ovariectomized rat. Endocrinology 96 (1975) 50-56
23. Lincoln G.A., Andersson H., and Loudon A. Clock genes in calendar cells as the basis of annual timekeeping in mammals-a unifying hypothesis. J. Endocrinol. 179 (2003) 1-13
24. Lloyd J.M., and Childs G.V. Changes in the number of GnRH-receptive cells during the rat estrous cycle: biphasic effects of estradiol. Neuroendocrinology 48 (1988) 138-146
25. Marian J., Cooper R.L., and Conn P.M. Regulation of the rat pituitary gonadotropin-releasing hormone receptor. Mol. Pharmacol. 19 (1981) 399-405
26. Maya-Nunez G., and Conn P.M. Transcriptional regulation of the gonadotropin-releasing hormone receptor gene is mediated in part by a putative repressor element and by the cyclic adenosine 3′,5′-monophosphate response element. Endocrinology 140 (1999) 3452-3458
27. Millar R.P., Lu Z.L., Pawson A.J., Flanagan C.A., Morgan K., and Maudsley S.R. Gonadotropin-releasing hormone receptors. Endocr. Rev. 25 (2004) 235-275
28. Miller B.H., Olson S.L., Turek F.W., Levine J.E., Horton T.H., and Takahashi J.S. Circadian clock mutation disrupts estrous cyclicity and maintenance of pregnancy. Curr. Biol. 14 (2004) 1367-1373
29. Morse D., Cermakian N., Brancorsini S., Parvinen M., and Sassone-Corsi P. No circadian rhythms in testis: Period1 expression is clock independent and developmentally regulated in the mouse. Mol. Endocrinol. 17 (2003) 141-151
30. Mosko S.S., and Moore R.Y. Neonatal ablation of the suprachiasmatic nucleus. Effects on the development of the pituitary-gonadal axis in the female rat. Neuroendocrinology 29 (1979) 350-361
31. Norwitz E.R., Xu S., Jeong K.H., Bedecarrats G.Y., Winebrenner L.D., Chin W.W., and Kaiser U.B. Activin A augments GnRH-mediated transcriptional activation of the mouse GnRH receptor gene. Endocrinology 143 (2002) 985-997
32. Oishi K., Miyazaki K., Kadota K., Kikuno R., Nagase T., Atsumi G., Ohkura N., Azama T., Mesaki M., Yukimasa S., Kobayashi H., Iitaka C., Umehara T., Horikoshi M., Kudo T., Shimizu Y., Yano M., Monden M., Machida K., Matsuda J., Horie S., Todo T., and Ishida N. Genome-wide expression analysis of mouse liver reveals CLOCK-regulated circadian output genes. J. Biol. Chem. 278 (2003) 41519-41527
33. Olcese J., Domagalski R., Bednorz A., Weaver D.R., Urbanski H.F., Reuss S., and Middendorff R. Expression and regulation of mPer1 in immortalized GnRH neurons. Neuroreport 14 (2003) 613-618
34. Olcese J., McArdle C.A., Middendorff R., and Greenland K. Pituitary adenylate cyclase-activating peptide and vasoactive intestinal peptide receptor expression in immortalized LHRH neurons. J. Neuroendocrinol. 9 (1997) 937-943
35. Olcese J., Sikes H.E., and Resuehr D. Induction of PER1 mRNA expression in immortalized gonadotropes by gonadotropin-releasing hormone (GnRH): involvement of protein kinase C and MAP kinase signaling. Chronobiol. Int. 23 (2006) 143-150
36. Pando M.P., Morse D., Cermakian N., and Sassone-Corsi P. Phenotypic rescue of a peripheral clock genetic defect via SCN hierarchical dominance. Cell 110 (2002) 107-117
37. Reppert S.M., and Weaver D.R. Coordination of circadian timing in mammals. Nature 418 (2002) 935-941
38. Ripperger J.A., Shearman L.P., Reppert S.M., and Schibler U. CLOCK, an essential pacemaker component, controls expression of the circadian transcription factor DBP. Genes Dev. 14 (2000) 679-689
39. Sadie H., Styger G., and Hapgood J. Expression of the mouse gonadotropin-releasing hormone receptor gene in alpha T3-1 gonadotrope cells is stimulated by cyclic 3′,5′-adenosine monophosphate and protein kinase A, and is modulated by Steroidogenic factor-1 and Nur77. Endocrinology 144 (2003) 1958-1971
40. Savoy-Moore R.T., Schwartz N.B., Duncan J.A., and Marshall J.C. Pituitary gonadotropin-releasing hormone receptors during the rat estrous cycle. Science 209 (1980) 942-944
41. Schirman-Hildesheim T.D., Ben-Aroya N., and Koch Y. Daily GnRH and GnRH-receptor mRNA expression in the ovariectomized and intact rat. Mol. Cell Endocrinol. 252 (2006) 120-125
42. Shearman L.P., Sriram S., Weaver D.R., Maywood E.S., Chaves I., Zheng B., Kume K., Lee C.C., van der Horst G.T., Hastings M.H., and Reppert S.M. Interacting molecular loops in the mammalian circadian clock. Science 288 (2000) 1013-1019
43. van der Beek E.M., Wiegant V.M., van Oudheusden H.J., van der Donk H.A., van den Hurk R., and Buijs R.M. Synaptic contacts between gonadotropin-releasing hormone-containing fibers and neurons in the suprachiasmatic nucleus and perichiasmatic area: an anatomical substrate for feedback regulation?. Brain Res. 755 (1997) 101-111
44. von Gall C. Rhythmic clock gene expression in the hypophyseal pars tuberalis is regulated by melatonin. Ann Anat 185 (2003) 301-302
45. White B.R., Duval D.L., Mulvaney J.M., Roberson M.S., and Clay C.M. Homologous regulation of the gonadotropin-releasing hormone receptor gene is partially mediated by protein kinase C activation of an activator protein-1 element. Mol. Endocrinol. 13 (1999) 566-577
46. Wise M.E., Nieman D., Stewart J., and Nett T.M. Effect of number of receptors for gonadotropin-releasing hormone on the release of luteinizing hormone. Biol. Reprod. 31 (1984) 1007-1013
47. Wurmbach E., Yuen T., Ebersole B.J., and Sealfon S.C. Gonadotropin-releasing hormone receptor-coupled gene network organization. J. Biol. Chem. 276 (2001) 47195-47201
48. Yamazaki S., Numano R., Abe M., Hida A., Takahashi R., Ueda M., Block G.D., Sakaki Y., Menaker M., and Tei H. Resetting central and peripheral circadian oscillators in transgenic rats. Science 288 (2000) 682-685
49. Yoo S.H., Ko C.H., Lowrey P.L., Buhr E.D., Song E.J., Chang S., Yoo O.J., Yamazaki S., Lee C., and Takahashi J.S. A noncanonical E-box enhancer drives mouse Period2 circadian oscillations in vivo. Proc. Natl. Acad. Sci. U.S.A. 102 (2005) 2608-2613
50. Zylka M.J., Shearman L.P., Weaver D.R., and Reppert S.M. Three period homologs in mammals: differential light responses in the suprachiasmatic circadian clock and oscillating transcripts outside of brain. Neuron 20 (1998) 1103-1110