Emergency Department Procedural Sedation with Propofol: Is it Safe?

Journal of Emergency Medicine

Volumn 33, Issue 4, 2007, Pages 355-361

  Weaver, Christopher S ^a   Hauter, William E ^a   Brizendine, Edward J ^a   Cordell, William H ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

complications; Procedural sedation; propofol

Indexed keywords

PROPOFOL;

ADULT; AIRWAY OBSTRUCTION; APNEA; ARTICLE; DRUG SAFETY; EMERGENCY WARD; FEMALE; HEALTH CENTER; HUMAN; HYPOVENTILATION; HYPOXEMIA; HYPOXIA; INJURY; INTUBATION; JAW THRUST; MAJOR CLINICAL STUDY; MALE; OXYGEN CONCENTRATION; OXYGEN TENSION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; PROSPECTIVE STUDY; SEDATION; SIDE EFFECT; UNSPECIFIED SIDE EFFECT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; CONSCIOUS SEDATION; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; HYPNOTICS AND SEDATIVES; MALE; MIDDLE AGED; PROPOFOL; PROSPECTIVE STUDIES;

EID: 36549054656     PISSN: 07364679     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jemermed.2007.03.014     Document Type: Article

References (41)

1. Bassett K.E., Anderson J.L., Pribble C.G., and Guenther E. Propofol for procedural sedation in children in the emergency department. Ann Emerg Med 42 (2003) 773-782
2. Havel Jr. C.J., Strait R.T., and Hennes H. A clinical trial of propofol vs midazolam for procedural sedation in a pediatric emergency department. Acad Emerg Med 6 (1999) 989-997
3. Skokan E.G., Pribble C., Bassett K.E., and Nelson D.S. Use of propofol sedation in a pediatric emergency department: a prospective study. Clin Pediatr (Phila) 40 (2001) 663-671
4. Miner J.R., Biros M., Krieg S., Johnson C., Heegaard W., and Plummer W. Randomized clinical trial of propofol versus methohexital for procedural sedation during fracture and dislocation reduction in the emergency department. Acad Emerg Med 10 (2003) 931-937
5. Taylor D.M., O'Brien D., Ritchie P., Pasco J., and Cameron P. Propofol versus midazolam/fentanyl for reduction of anterior shoulder dislocation. Acad Emerg Med 12 (2005) 13-19
6. Burton J.H., Miner J.R., Shipley E.R., Strout T.D., Becker C., and Thode H.C. Propofol for emergency department procedural sedation and analgesia: a tale of three centers. Acad Emerg Med 13 (2006) 24-30
7. Swanson E.R., Seaberg D.C., and Mathias S. The use of propofol for sedation in the emergency department. Acad Emerg Med 3 (1996) 234-238
8. Miner J.R., Heegaard W., and Plummer D. End-tidal carbon dioxide monitoring during procedural sedation. Acad Emerg Med 9 (2002) 275-280
9. Miner J.R., Biros M., Seigel T., and Ross K. The utility of the bispectral index in procedural sedation with propofol in the emergency department. Acad Emerg Med 12 (2005) 190-196
10. Miner J.R., Biros M., Heegaard W., and Plummer D. Bispectral electroencephalographic analysis of patients undergoing procedural sedation in the emergency department. Acad Emerg Med 6 (2003) 638-643
11. Miner J.R., Martel M.L., Meyer M., Reardon R., and Biros M. Procedural sedation of critically ill patients in the emergency department. Acad Emerg Med 12 (2005) 124-128
12. Guenther E., Pribble C.G., Junkins Jr. E.P., Kadish H.A., Bassett K.E., and Nelson D.S. Propofol sedation by emergency physicians for elective pediatric outpatient procedures. Ann Emerg Med 42 (2003) 783-791
13. Jackson R., and Carley S. Towards evidence based emergency medicine: best BETs from the Manchester Royal Infirmary. Use of propofol for sedation in the emergency department. Emerg Med J 18 (2001) 378-379
14. Acworth J.P., Purdie D., and Clark R.C. Intravenous ketamine plus midazolam is superior to intranasal midazolam for emergency paediatric procedural sedation. Emerg Med J 18 (2001) 39-45
15. Austin T., Vilke G.M., Nyheim E., Kelly D., and Chan T.C. Safety and effectiveness of methohexital for procedural sedation in the emergency department. J Emerg Med 24 (2003) 315-318
16. Chudnofsky C.R., Weber J.E., Soyanoff P.J., et al. A combination of midazolam and ketamine for procedural sedation and analgesia in adult emergency department patients. Acad Emerg Med 7 (2000) 228-235
17. Ellis D.Y., Husain H.M., Saetta J.P., and Walker T. Procedural sedation in paediatric minor procedures: a prospective audit on ketamine use in the emergency department. Emerg Med J 21 (2004) 286-289
18. Everitt I.J., and Barnett P. Comparison of two benzodiazepines used for sedation of children undergoing suturing of a laceration in an emergency department. Pediatr Emerg Care 18 (2002) 72-74
19. Everitt I., Younge P., and Barnett P. Paediatric sedation in emergency department: what is our practice?. Emerg Med (Fremantle) 14 (2002) 62-66
20. Godwin S.A., Caro D.A., Wolf S.J., et al., American College of Emergency Physicians. Clinical policy: procedural sedation and analgesia in the emergency department. Ann Emerg Med 45 (2005) 177-196
21. Kennedy R.M., Luhmann J.D., and Luhmann S.J. Emergency department management of pain and anxiety related to orthopedic fracture care: a guide to analgesic techniques and procedural sedation in children. Paediatr Drugs 6 (2004) 11-31
22. Luhmann J.D., Kennedy R.M., Porter F.L., Miller J.P., and Jaffe D.M. A randomized clinical trial of continuous-flow nitrous oxide and midazolam for sedation of young children during laceration repair. Ann Emerg Med 37 (2001) 20-27
23. McCarty E.C., Mencio G.A., Walker L.A., and Green N.E. Ketamine sedation for the reduction of children's fractures in the emergency department. J Bone Joint Surg 82-A (2000) 912-918
24. McGlone R., Fleet T., Durham S., and Hollis S. A comparison of intramuscular ketamine with high dose intramuscular midazolam with and without intranasal flumazenil in children before suturing. Emerg Med J 18 (2001) 34-38
25. McGlone R.G., Howes M.C., and Joshi M. The Lancaster experience of 2.0 to 2.5 mg/kg intramuscular ketamine for paediatric sedation: 501 cases and analysis. Emerg Med J 21 (2004) 290-295
26. Nelson D.S., Hoagland J.R., and Kunkel N.C. Costs of sedation using oral midazolam: money, time, and parental attitudes. Pediatr Emerg Care 16 (2000) 80-84
27. Pershad J., and Godambe S.A. Propofol for procedural sedation in the pediatric emergency department. J Emerg Med 27 (2004) 11-14
28. Pitetti R.D., Singh S., and Pierce M.C. Safe and efficacious use of procedural sedation and analgesia by nonanesthesiologists in a pediatric emergency department. Arch Pediatr Adolesc Med 157 (2003) 1090-1096
29. Rothermel L.K. Newer pharmacologic agents for procedural sedation of children in the emergency department-etomidate and propofol. Curr Opin Pediatr 15 (2003) 200-203
30. Ruth W.J., Burton J.H., and Bock A.J. Intravenous etomidate for procedural sedation in emergency department patients. Acad Emerg Med 8 (2001) 13-18
31. Vinson D.R., and Bradbury D.R. Etomidate for procedural sedation in emergency medicine. Ann Emerg Med 39 (2002) 592-598
32. Ward K.R., and Yealy D.M. Systemic analgesia and sedation in managing orthopedic emergencies. Emerg Med Clin North Am 18 (2000) 141-166
33. Wathen J.E., Roback M.G., Mackenzie T., and Bothner J.P. Does midazolam alter the clinical effects of intravenous ketamine sedation in children?. A double-blind, randomized, controlled, emergency department trial. Ann Emerg Med 36 (2000) 579-588
34. Younge P.A., and Kendall J.M. Sedation for children requiring wound repair: a randomised controlled double blind comparison of oral midazolam and oral ketamine. Emerg Med J 18 (2001) 30-33
35. Diprivan 1% (propofol) package insert (2002), AstraZeneca Pharmaceuticals LP, Wilmington, DE 2004
36. American Society of Anesthesiologists. Physical Status Classification System. Available at. http://www.asahq.org/clinical/physicalstatus.htm Accessed January 28, 2004
37. Green S.M., and Krauss B. Pulmonary aspiration risk during emergency department procedural sedation-an examination of the role of fasting and sedation depth. Acad Emerg Med 9 (2002) 35-42
38. American College of Emergency Physicians. Clinical policy for procedural sedation and analgesia in the emergency department. Ann Emerg Med 31 (1998) 663-677
39. Pohlgeers A.P., Friedland L.R., and Keegan-Jones L. Combination fentanyl and diazepam for pediatric conscious sedation. Acad Emerg Med 2 (1995) 879-883
40. O'Brien J.F., Falk J.L., Carey B.E., and Malone L.C. Rectal thiopental compared with intramuscular meperidine, promethazine, and chlorpromazine for pediatric sedation. Ann Emerg Med 20 (1991) 644-647
41. Block Jr. F.E., Reynolds K.M., Kajaste T., and Nourijelyani K. Pre-operative oximetry and capnometry: potential respiratory screening tools. Int J Clin Monit Comput 13 (1996) 153-156