Sedation for children requiring wound repair: A randomised controlled double blind comparison of oral midazolam and oral ketamine

Emergency Medicine Journal

Volumn 18, Issue 1, 2001, Pages 30-33

  Younge, Paul A ^a   Kendall, Jason M ^b  

^a BRISTOL ROYAL HOSPITAL FOR CHILDREN   (United Kingdom)

^b FRENCHAY HOSPITAL   (United Kingdom)

Author keywords

Children; Ketamine; Midazolam; Suturing

Indexed keywords

KETAMINE; LOCAL ANESTHETIC AGENT; MIDAZOLAM;

AGITATION; ANXIETY; ARTICLE; ATAXIA; BEHAVIOR DISORDER; CHILD; CHILD HEALTH CARE; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE RESPONSE; DOSE TIME EFFECT RELATION; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG MONITORING; DRUG TOLERANCE; DYSPHORIA; FEMALE; HOSPITAL DISCHARGE; HUMAN; INJECTION; LACERATION; LOCAL ANESTHESIA; MAJOR CLINICAL STUDY; MALE; OXYGEN SATURATION; PROSPECTIVE STUDY; PULSE OXIMETRY; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SEDATION; SUTURE; VOMITING; WOUND HEALING;

EID: 0035689417     PISSN: 13510622     EISSN: None     Source Type: Journal    
DOI: 10.1136/emj.18.1.30     Document Type: Article

References (18)

1. Kendall JM, Charters A, Mccabe SE. Topical anaesthesia for children's lacerations : an acceptable approach. J Accid Emerg Med 1996;13:119-22.
2. Vernon DTA, Schulman JL, Foley JM. Changes in children's behaviour after hospitalisation. Am J Dis Child 1966;111:581-93.
3. Eckenhoff JE. Relationship of anaesthesia to post operative personality changes in children. Am J Dis Child 1953;86: 587-91.
4. McClusky A, Meakin GH. Oral administration of midazolam as a premedicant for paediatric day-case anaesthesia. Anaesthesia 1994;49:782-5.
5. The Pediatric Committee of the American College of Emergency Physicians. Paediatric Analgesia and Sedation. Ann Emerg Med 1994;23:237-50.
6. Hennes HM, Wagner V, Bonadio W, et al. The effect of oral midazolam on anxiety of preschool children during laceration repair. Ann Emerg Med 1990;19:1006-9.
7. Taiwo B, Flowers M, Zoltie N. Reducing children's' fear when undergoing painful procedures. Arch Emerg Med 1992;9:306-9.
8. Davies FC, Waters M. Oral midazolam for conscious sedation of children during minor procedures. J Accid Emerg Med 1998;15:244-8.
9. McMillian CO, Sparth-Schopfer IA, et al. Premedication of children with oral midazolam. Can J Anaesth 1992;39:545-50.
10. White PF, Way WL, Trevor AJ. Ketamine-its pharmacology and therapeutic uses. Anesthesiology 1982;56:119-36.
11. Green SM, Rothrock SG, Lynch EL, et al. Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases. Ann Emerg Med 1998;31:688-97.
12. Qureshi FA, Mellis PT, McFadden MA. Efficacy of oral ketamine for providing sedation and analgesia to children requiring laceration repair. Pediatr Emerg Care 1995;11:93-7.
13. Sussman DR. A comparative evaluation of ketamine anesthesia in children and adults. Anaethesiology 1974;40: 459-64.
14. McGlone RG, Ranasinghe S, Durham S. An alternative to "brutacaine": a comparison of low dose intramuscular ketamine with intranasal midazolam before suturing. J Accid Emerg Med 1998;15:231-6.
15. Weldon CB, Watcha MF, White PF. Oral midazolam in children: effect of time and adjunctive therapy. Anesth Analg 1992;75:51-5.
16. Malinovsky JM, Populaire C, Cozian A, et al. Premedication with midazoalm in children. Effect of intranansal, rectal and oral routes on plasma midazolam concentrations. Anaesthesia 1995;50:351-4.
17. Gutstein HB, Johnson KL, Heard MB, et al. Oral ketamine preanesthetic medication in children. Anesthesiology 1992; 76:28-33.
18. Walker J. the use of oral midazolam in Accident and Emergency to reduce anxiety in children. Accid Emerg Nurse 1996;4:110-13.