Regulation of the Na,K-ATPase: Special implications for cardiovascular complications of metabolic syndrome

Pathophysiology

Volumn 14, Issue 3-4, 2007, Pages 153-158

  Chibalin, Alexander V ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Diabetes mellitus; Diabetic complications; Metabolic syndrome; Na,K ATPase; Potassium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); INSULIN; POTASSIUM ION;

ARTICLE; CARDIOVASCULAR DISEASE; DIABETIC NEPHROPATHY; DIABETIC NEUROPATHY; DIABETIC RETINOPATHY; ENZYME ACTIVITY; HEART ARRHYTHMIA; HEART FAILURE; HUMAN; HYPERKALEMIA; MEMBRANE DEPOLARIZATION; METABOLIC SYNDROME X; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SKELETAL MUSCLE;

EID: 36549051289     PISSN: 09284680     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pathophys.2007.09.004     Document Type: Article

References (82)

1. +]. Semin. Nephrol. 25 (2005) 335-342
2. Lingrel J., and Kuntzweiler T. Na,K-ATPase. J. Biol. Chem. 269 (1994) 19659-19662
3. Ewart H.S., and Klip A. Hormonal regulation of the Na,K-ATPase: mechanisms underlying rapid and sustained changes in pump activity. Am. J. Physiol. 269 (1995) C295-C311
4. Al-Khalili L., Kotova O., Tsuchida H., Ehren I., Feraille E., Krook A., and Chibalin A.V. ERK1/2 mediates insulin stimulation of Na,K-ATPase by phosphorylation of the alpha-subunit in human skeletal muscle cells. J. Biol. Chem. 279 (2004) 25211-25218
5. Beguin P., Beggah A.T., Chibalin A.V., Burgener-Kairuz P., Jaisser F., Mathews P.M., Rossier B.C., Cotecchia S., and Geering K. Phosphorylation of the Na,K-ATPase alpha-subunit by protein kinase A and C in vitro and in intact cells. Identification of a novel motif for PKC-mediated phosphorylation. J. Biol. Chem. 269 (1994) 24437-24445
6. Bertorello A.M., Aperia A., Walaas S.I., Nairn A.C., and Greengard P. Phosphorylation of the catalytic subunit of Na,K-ATPase inhibits the activity of the enzyme. Proc. Natl. Acad. Sci. U.S.A. 88 (1991) 11359-11362
7. Chibalin A.V., Lopina O.D., Petukhov S.P., and Vasilets L.A. Phosphorylation of the Na,K-ATPase by Ca,phospholipid-dependent and cAMP-dependent protein kinases. Mapping of the region phosphorylated by Ca,phospholipid-dependent protein kinase. J. Bioenerg. Biomembr. 25 (1993) 61-66
8. Feraille E., Carranza M.L., Gonin S., Beguin P., Pedemonte C., Rousselot M., Caverzasio J., Geering K., Martin P.Y., and Favre H. Insulin-induced stimulation of Na,K-ATPase activity in kidney proximal tubule cells depends on phosphorylation of the alpha-subunit at Tyr-10. Mol. Biol. Cell 10 (1999) 2847-2859
9. Kotova O., Al-Khalili L., Talia S., Hooke C., Fedorova O.V., Bagrov A.Y., and Chibalin A.V. Cardiotonic steroids stimulate glycogen synthesis in human skeletal muscle cells via a Src- and ERK1/2-dependent mechanism. J. Biol. Chem. 281 (2006) 20085-20094
10. Chibalin A., Vasilets L., Hennekes H., Pralong D., and Geering K. Phosphorylation of Na,K-ATPase alpha-subunits in microsomes and in homogenates of Xenopus oocytes resulting from the stimulation of protein kinase A and protein kinase C. J. Biol. Chem. 267 (1992) 22378-22384
11. + transport in skeletal muscle. Physiol. Rev. 66 (1986) 542-580
12. Briggs A.P., Koenig I., Doisy E.A., and Weber C.J. Some changes in the composition of blood due to the injection of insulin. J. Biol. Chem. 58 (1924) 721-730
13. Weil E., Sasson S., and Gutman Y. Mechanism of insulin-induced activation of Na,K-ATPase in isolated rat soleus muscle. Am. J. Physiol. 261 (1991) C224-C230
14. Sampson S.R., Brodie C., and Alboim S.V. Role of protein kinase C in insulin activation of the Na-K pump in cultured skeletal muscle. Am. J. Physiol. 266 (1994) C751-C758
15. Al-Khalili L., Yu M., and Chibalin A.V. Na,K-ATPase trafficking in skeletal muscle: insulin stimulates translocation of both alpha 1- and alpha 2-subunit isoforms. FEBS Lett. 536 (2003) 198-202
16. Hundal H.S., Marette A., Mitsumoto Y., Ramlal T., Blostein R., and Klip A. Insulin induces translocation of the alpha 2 and beta 1 subunits of the Na,K-ATPase from intracellular compartments to the plasma membrane in mammalian skeletal muscle. J. Biol. Chem. 267 (1992) 5040-5043
17. Hundal H.S., Maxwell D.L., Ahmed A., Darakhshan F., Mitsumoto Y., and Klip A. Subcellular distribution and immunocytochemical localization of Na,K-ATPase subunit isoforms in human skeletal muscle. Mol. Membr. Biol. 11 (1994) 255-262
18. Marette A., Krischer J., Lavoie L., Ackerley C., Carpentier J.L., and Klip A. Insulin increases the Na,K-ATPase alpha 2-subunit in the surface of rat skeletal muscle: morphological evidence. Am. J. Physiol. 265 (1993) C1716-C1722
19. Bia M.J., and DeFronzo R.A. Extrarenal potassium homeostasis. Am. J. Physiol. 240 (1981) F257-F268
20. Jamison R.L. Potassium recycling. Kidney Int. 31 (1987) 695-703
21. DeFronzo R.A., Sherwin R.S., Dillingham M., Hendler R., Tamborlane W.V., and Felig P. Influence of basal insulin and glucagon secretion on potassium and sodium metabolism. Studies with somatostatin in normal dogs and in normal and diabetic human beings. J. Clin. Invest. 61 (1978) 472-479
22. + pump regulation and skeletal muscle contractility. Physiol. Rev. 83 (2003) 1269-1324
23. Landin K., Lindgarde F., Saltin B., and Wilhelmsen L. Increased skeletal muscle Na/K-ratio in obese men, but not in women, with glucose intolerance. J. Intern. Med. 225 (1989) 89-94
24. Mimura M., Makino H., Kanatsuka A., Asai T., and Yoshida S. Reduction of erythrocyte Na,K-ATPase activity in type 2 (non-insulin-dependent) diabetic patients with microalbuminuria. Horm. Metab. Res. 26 (1994) 33-38
25. Rodrigo R., Bachler J.P., Araya J., Prat H., and Passalacqua W. Relationship between Na,K-ATPase activity, lipid peroxidation and fatty acid profile in erythrocytes of hypertensive and normotensive subjects. Mol. Cell. Biochem. 303 (2007) 73-81
26. 3H]ouabain binding in identical twins, discordant for Type 2 diabetes. J. Clin. Endocrinol. Metab. 86 (2001) 859-866
27. 3H]ouabain binding capacity of skeletal muscle in relatives of patients with Type 2 diabetes: effect of dexamethasone. Metabolism 51 (2002) 1331-1339
28. Vrbjar N., Strelkova S., Stefek M., Kyselova Z., and Gajdosikova A. Effect of the pyridoindole antioxidant stobadine on sodium handling of renal Na,K-ATPase in rats with streptozotocin-induced diabetes. Acta Diabetol. 41 (2004) 172-178
29. Ver A., Csermely P., Banyasz T., Kovacs T., and Somogyi J. Alterations in the properties and isoform ratios of brain Na,K-ATPase in streptozotocin diabetic rats. Biochim. Biophys. Acta 1237 (1995) 143-150
30. Ver A., Szanto I., Banyasz T., Csermely P., Vegh E., and Somogyi J. Changes in the expression of Na,K-ATPase isoenzymes in the left ventricle of diabetic rat hearts: effect of insulin treatment. Diabetologia 40 (1997) 1255-1262
31. Kjeldsen K., Braendgaard H., Sidenius P., Larsen J.S., and Norgaard A. Diabetes decreases Na-K pump concentration in skeletal muscles, heart ventricular muscle, and peripheral nerves of rat. Diabetes 36 (1987) 842-848
32. Schmidt T.A., Hasselbalch S., Farrell P.A., Vestergaard H., and Kjeldsen K. Human and rodent muscle Na,K-ATPase in diabetes related to insulin, starvation, and training. J. Appl. Physiol. 76 (1994) 2140-2146
33. DeFronzo R.A. Obesity is associated with impaired insulin-mediated potassium uptake. Metabolism 37 (1988) 105-108
34. Arslanian S., and Austin A. Impaired insulin mediated potassium uptake in adolescents with IDDM. Biochem. Med. Metab. Biol. 46 (1991) 364-372
35. Smoller S., Rashid K., Perez G.O., Oster J.R., and Vaamonde C.A. Blunted kaliuresis after an acute oral potassium load in diabetes mellitus. Am. J. Med. Sci. 295 (1988) 114-121
36. Bundgaard H., and Kjeldsen K. Regulation of myocardial and skeletal muscle Na,K-ATPase in diabetes mellitus in humans and animals. Adv. Exp. Med. Biol. 498 (2001) 319-322
37. Kjeldsen K., Norgaard A., and Gheorghiade M. Myocardial Na,K-ATPase: the molecular basis for the hemodynamic effect of digoxin therapy in congestive heart failure. Cardiovasc. Res. 55 (2002) 710-713
38. Schwinger R.H., Bundgaard H., Muller-Ehmsen J., and Kjeldsen K. The Na,K-ATPase in the failing human heart. Cardiovasc. Res. 57 (2003) 913-920
39. Baba A., Yoshikawa T., Mitamura H., and Ogawa S. Erythrocyte Na,K-ATPase activity in patients with congestive heart failure. Int. J. Cardiol. 69 (1999) 117-125
40. Muller-Ehmsen J., McDonough A.A., Farley R.A., and Schwinger R.H. Sodium pump isoform expression in heart failure: implication for treatment. Basic Res. Cardiol. 97 Suppl. 1 (2002) I25-I30
41. Helwig B., Schreurs K.M., Hansen J., Hageman K.S., Zbreski M.G., McAllister R.M., Mitchell K.E., and Musch T.I. Training-induced changes in skeletal muscle Na-K pump number and isoform expression in rats with chronic heart failure. J. Appl. Physiol. 94 (2003) 2225-2236
42. Musch T.I., Wolfram S., Hageman K.S., and Pickar J.G. Skeletal muscle ouabain binding sites are reduced in rats with chronic heart failure. J. Appl. Physiol. 92 (2002) 2326-2334
43. McDonough A.A., Thompson C.B., and Youn J.H. Skeletal muscle regulates extracellular potassium. Am. J. Physiol. Renal Physiol. 282 (2002) F967-F974
44. +-ATPase by insulin: why and how?. Mol. Cell Biochem. 182 (1998) 121-133
45. Schoner W., and Scheiner-Bobis G. Endogenous cardiac glycosides: hormones using the sodium pump as signal transducer. Semin. Nephrol. 25 (2005) 343-351
46. Schoner W., and Scheiner-Bobis G. Endogenous and exogenous cardiac glycosides: their roles in hypertension, salt metabolism, and cell growth. Am. J. Physiol. Cell. Physiol. (2007) 10.1152/ajpcello.00098.2007
47. Xie Z., and Askari A. Na/K-ATPase as a signal transducer. Eur. J. Biochem. 269 (2002) 2434-2439
48. Kotova O., Galuska D., Essen-Gustavsson B., and Chibalin A.V. Metabolic and signaling events mediated by cardiotonic steroid ouabain in rat skeletal muscle. Cell. Mol. Biol. (Noisy-le-grand) 52 (2006) 48-57
49. Bagrov Y.Y., Manusova N.B., Egorova I.A., Fedorova O.V., and Bagrov A.Y. Endogenous digitalis-like ligands and Na/K-ATPase inhibition in experimental diabetes mellitus. Front Biosci. 10 (2005) 2257-2262
50. Bagrov Y.Y., Manusova N.B., Egorova I.A., Frolova E.V., Fedorova O.V., and Bagrov A.Y. Marinobufagenin, an endogenous inhibitor of alpha-1Na/K-ATPase, is a novel factor in pathogenesis of diabetes mellitus. Dokl. Biol. Sci. 404 (2005) 333-337
51. Wasada T., Kuroki H., Naruse M., et al. Insulin resistance is associated with high plasma ouabain-like immunoreactivity concentration in NIDDM. Diabetologia 38 (1995) 792-797
52. Fink D.J., Datta S., and Mata M. Isoform specific reductions in Na,K-ATPase catalytic alpha subunits in the nerve of rats with streptozotocin-induced diabetes. J. Neurochem. 63 (1994) 1782-1786
53. Nowak T.V., Castelaz C., Ramaswamy K., and Weisbruch J.P. Impaired rodent vagal nerve sodium-potassium-ATPase activity in streptozotocin diabetes. J. Lab. Clin. Med. 125 (1995) 182-186
54. Scarpini E., Bianchi R., Moggio M., Sciacco M., Fiori M.G., and Scarlato G. Decrease of nerve Na,K-ATPase activity in the pathogenesis of human diabetic neuropathy. J. Neurol. Sci. 120 (1993) 159-167
55. Bensaoula T., and Ottlecz A. Biochemical and ultrastructural studies in the neural retina and retinal pigment epithelium of STZ-diabetic rats: effect of captopril. J. Ocul. Pharmacol. Ther. 17 (2001) 573-586
56. Kowluru R., Jirousek M., Stramm L., Farid N., Engerman R., and Kern T. Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases. Diabetes 47 (1998) 464-469
57. Ottlecz A., and Bensaoula T. Captopril ameliorates the decreased Na,K-ATPase activity in the retina of streptozotocin-induced diabetic rats. Invest. Ophthalmol. Vis. Sci. 37 (1996) 1633-1641
58. Cohen M.P., Dasmahapatra A., and Shapiro E. Reduced glomerular sodium/potassium adenosine triphosphatase activity in acute streptozocin diabetes and its prevention by oral sorbinil. Diabetes 34 (1985) 1071-1074
59. Tsimaratos M., Coste T.C., Djemli-Shipkolye A., Vague P., Pieroni G., and Raccah D. Gamma-linolenic acid restores renal medullary thick ascending limb Na,K-ATPase activity in diabetic rats. J. Nutr. 131 (2001) 3160-3165
60. Reddi A.S., Dasmahapatra A., Jyothirmayi G.N., and Jayasundaramma B. Erythrocyte Ca, Na/K-ATPase in long-term streptozotocin diabetic rats. Effect of good glycemic control and a Ca antagonist. Am. J. Hypertens. 5 (1992) 863-868
61. Djemli-Shipkolye A., Coste T., Raccah D., Vague P., Pieroni G., and Gerbi A. Na,K-ATPase alterations in diabetic rats: relationship with lipid metabolism and nerve physiological parameters. Cell. Mol. Biol. (Noisy-le-grand) 47 (2001) 297-304
62. Sugimoto K., Murakawa Y., and Sima A.A. Diabetic neuropathy-a continuing enigma. Diab. Metab. Res. Rev. 16 (2000) 408-433
63. Perez G.O., Lespier L., Knowles R., Oster J.R., and Vaamonde C.A. Potassium homeostasis in chronic diabetes mellitus. Arch. Intern. Med. 137 (1977) 1018-1022
64. Chibalin A.V., Katz A.I., Berggren P.-O., and Bertorello A.M. Receptor-mediated inhibition of renal Na,K-ATPase is associated with endocytosis of its alpha- and beta-subunits. Am. J. Physiol. Cell Physiol. 273 (1997) C1458-C1465
65. Chibalin A.V., Pedemonte C.H., Katz A.I., Feraille E., Berggren P.-O., and Bertorello A.M. Phosphorylation of the catalytic alpha-subunit constitutes a triggering signal for Na,K-ATPase endocytosis. J. Biol. Chem. 273 (1998) 8814-8819
66. Craven P.A., and DeRubertis F.R. Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose. J. Clin. Invest. 83 (1989) 1667-1675
67. Inoguchi T., Battan R., Handler E., Sportsman J., Heath W., and King G. Preferential elevation of protein kinase C isoform betaII and diacylglycerol levels in the aorta and heart of diabetic rats: differential reversibility to glycemic control by islet cell transplantation. Proc. Natl. Acad. Sci. U.S.A. 89 (1992) 11059-11063
68. Ishii H., Jirousek M.R., Koya D., et al. Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor. Science 272 (1996) 728-731
69. Shiba T., Inoguchi T., Sportsman J.R., Heath W.F., Bursell S., and King G.L. Correlation of diacylglycerol level and protein kinase C activity in rat retina to retinal circulation. Am. J. Physiol. 265 (1993) E783-E793
70. Lee T.S., Saltsman K.A., Ohashi H., and King G.L. Activation of protein kinase C by elevation of glucose concentration: proposal for a mechanism in the development of diabetic vascular complications. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 5141-5145
71. Kim J., Rushovich E.H., Thomas T.P., Ueda T., Agranoff B.W., and Greene D.A. Diminished specific activity of cytosolic protein kinase C in sciatic nerve of streptozocin-induced diabetic rats and its correction by dietary myo-inositol. Diabetes 40 (1991) 1545-1554
72. Crider J.Y., Yorio T., Sharif N.A., and Griffin B.W. The effects of elevated glucose on Na/K-ATPase of cultured bovine retinal pigment epithelial cells measured by a new nonradioactive rubidium uptake assay. J. Ocul. Pharmacol. Ther. 13 (1997) 337-352
73. Raccah D., Lamotte-Jannot M.F., Issautier T., and Vague P. Effect of experimental diabetes on Na/K-ATPase activity in red blood cells, peripheral nerve and kidney. Diab. Metab. 20 (1994) 271-274
74. Beguin P., Peitsch M.C., and Geering K. Alpha 1 but not alpha 2 or alpha 3 isoforms of Na,K-ATPase are efficiently phosphorylated in a novel protein kinase C motif. Biochemistry 35 (1996) 14098-14108
75. Sima A.A., Zhang W., Sugimoto K., Henry D., Li Z., Wahren J., and Grunberger G. C-peptide prevents and improves chronic Type I diabetic polyneuropathy in the BB/Wor rat. Diabetologia 44 (2001) 889-897
76. Djemli-Shipkolye A., Gallice P., Coste T., Jannot M.F., Tsimaratos M., Raccah D., and Vague P. The effects ex vivo and in vitro of insulin and C-peptide on Na/K adenosine triphosphatase activity in red blood cell membranes of type 1 diabetic patients. Metabolism 49 (2000) 868-872
77. Ohtomo Y., Aperia A., Sahlgren B., Johansson B.L., and Wahren J. C-peptide stimulates rat renal tubular Na,K-ATPase activity in synergism with neuropeptide Y. Diabetologia 39 (1996) 199-205
78. Denton R.M., and Tavare J.M. Does mitogen-activated-protein kinase have a role in insulin action? The cases for and against. Eur. J. Biochem. 227 (1995) 597-611
79. Kitamura T., Kimura K., Jung B.D., Makondo K., Okamoto S., Canas X., Sakane N., Yoshida T., Saito M., et al. Proinsulin C-peptide rapidly stimulates mitogen-activated protein kinases in Swiss 3T3 fibroblasts: requirement of protein kinase C, phosphoinositide 3-kinase and pertussis toxin-sensitive G-protein. Biochem. J. 355 (2001) 123-129
80. Kitamura T., Kimura K., Makondo K., Furuya T., Suzuki M., Yoshida T., and Saito M. Proinsulin C-peptide increases nitric oxide production through mitogen-activated protein kinase-dependent transcriptional enhancement of endothelial nitric oxide synthase in rat aortic endothelial cells. Diabetologia 46 (2003) 1698-1705
81. Zhong Z., Davidescu A., Ehren I., Ekberg K., Jornvall H., Wahren J., and Chibalin A.V. C-peptide stimulates ERK1/2 and JNK MAP kinases via activation of protein kinase C in human renal tubular cells. Diabetologia 48 (2005) 187-197
82. Zhong Z., Kotova O., Davidescu A., Ehren I., Ekberg K., Jornvall H., Wahren J., and Chibalin A.V. C-peptide stimulates Na,K-ATPase via activation of ERK1/2 MAP kinases in human renal tubular cells. Cell. Mol. Life Sci. 61 (2004) 2782-2790