Trace analysis of icariin in human serum with dansyl chloride derivatization after oral administration of Epimedium decoction by liquid chromatography tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 860, Issue 2, 2007, Pages 166-172

  Gong, Yinhan ^a,b   Yip, See Chung ^a,b   Thamarai, Sennappan Kanagamani ^a   Zhang, Jie ^b   Lee, Hian Kee ^b   Yong, E L ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Epimedium decoction; Human clinical trial; Icariin; Liquid chromatography; Tandem mass spectrometry; Trace analysis

Indexed keywords

BIOACTIVITY; BODY FLUIDS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PLANTS (BOTANY); TRACE ANALYSIS;

DANSYL CHLORIDE; EPIMEDIUM DECOCTION; EPIMEDIUM HERBS; HUMAN CLINICAL TRIALS; ICARIIN; ORAL ADMINISTRATION; TANDEM MASS SPECTROMETRY; TRADITIONAL CHINESE MEDICINE; ULTRASENSITIVE LIQUID CHROMATOGRAPHY;

MEDICINE;

DANSYL CHLORIDE; EPIMEDIUM EXTRACT; ICARIIN;

ARTICLE; CHEMICAL REACTION; CONTROLLED STUDY; DERIVATIZATION; DRUG STRUCTURE; HUMAN; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUALITY CONTROL; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ADMINISTRATION, ORAL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DANSYL COMPOUNDS; FLAVONOIDS; HUMANS; PLANT EXTRACTS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EPIMEDIUM;

EID: 36549033692     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.10.045     Document Type: Article

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