Assessment of absorbed doses of carbaryl and associated health risks in a group of horticultural greenhouse workers

International Archives of Occupational and Environmental Health

Volumn 81, Issue 3, 2008, Pages 355-370

  Bouchard, Michèle ^a   Carrier, Gaétan ^a   Brunet, Robert C ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

1 Naphthol; Carbaryl; Risk assessment; Toxicokinetic model; Urinary biomarker

Indexed keywords

1 NAPHTHOL; BIOLOGICAL MARKER; CARBARIL;

ABSORPTION; AGRICULTURAL WORKER; ARTICLE; BIOLOGICAL MONITORING; CONCENTRATION RESPONSE; FEMALE; HORTICULTURE; HUMAN; HUMAN EXPERIMENT; MALE; MATHEMATICAL MODEL; OCCUPATIONAL EXPOSURE; OCCUPATIONAL HAZARD; RISK ASSESSMENT; SIMULATION; TOXICOKINETICS; URINALYSIS; URINARY EXCRETION;

AGRICULTURE; BIOLOGICAL MARKERS; CARBARYL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; HUMANS; INSECTICIDES; MALE; MODELS, STATISTICAL; OCCUPATIONAL EXPOSURE; QUEBEC; RISK ASSESSMENT;

EID: 36549012754     PISSN: 03400131     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00420-007-0220-1     Document Type: Article

References (36)

1. ACGIH (2006) Documentation of the threshold limit values and biological exposure indices, 7th edn. American Conference of Governmental Industrial Hygienists, Cincinnati, Ohio
2. Angerer J, Weiss T (2002) Biological monitoring: Prospects in occupational and environmental medicine. Wiley-VCH, Weinheim
3. Boeniger MF, Lowry LK, Rosenberg J (1993) Interpretation of urine results used to assess chemical exposure with emphasis on creatinine adjustments: A review. Am Ind Hyg Assoc J 54:615-627
4. Bouchard M, Pinsonneault L, Tremblay C, Weber J-P (2001) Biological monitoring of environmental exposure to polycyclic aromatic hydrocarbons in subjects living in the vicinity of a creosote impregnation plant. Int Arch Occup Environ Health 74:505-513
5. Bouchard M, Gosselin NH, Brunet RC, Samuel O, Dumoulin MJ, Carrier G (2003) A toxicokinetic model of malathion and its metabolites as a tool to assess human exposure and risk through measurements of urinary biomarkers. Toxicol Sci 73:182-194
6. Bouchard M, Carrier G, Brunet RC, Gosselin NH, Bonvalot Y (2005) Determination of biological reference values for chlorpyrifos metabolites in human urine using a toxicokinetic model. J Occup Environ Health 2(3):155-168
7. Bronaugh RL, Maibach HI (1999) Percutaneous absorption. Drugs, cosmetics, mechanisms and methodology, 3rd edn. Marcel Dekker, NewYork
8. Carrier G, Brunet RC (1999) A toxicokinetic model to assess the risk of azinphosmethyl exposure in humans through measures of urinary elimination of alkylphosphates. Toxicol Sci 47:23-32
9. CDC (2005) Third national report on human exposure to environmental chemicals. Department of Health and Human Services, Centers for Disease Control and Prevention, Atlanta, Georgia, pp 349-384
10. Chin BH, Eldridge JM, Sullivant LJ (1974) Metabolism of carbaryl by selected human tissues using an organ-maintenance technique. Clin Toxicol 7(1):37-56
11. Curtis G, Fogel M (1970) Creatinine excretion: Diurnal variation and variability of whole and part-day measures. Psychosom Med 32:337-350
12. Deutsche Forschungsgemeinschaft (DFG) (2006) List of MAK and BAT values 2006: Maximum concentrations and biological tolerance values at the workplace. Commission for the investigation of health hazards of chemical compounds in the work area, report 42. Wiley-VCH, Weinheim
13. Ding YS, Trommel JS, Yan XZJ, Ashley D, Watson CH (2005) Determination of 14 polycyclic aromatic hydrocarbons in mainstream smoke from domestic cigarettes. Environ Sci Technol 39(2):471-478
14. Feldmann RJ, Maibach HI (1974) Percutaneous penetration of some pesticides and herbicides in man. Toxicol Appl Pharmacol 28:126-132
15. Frank R, Braun HE, Ripley BD (1989) Monitoring Ontario-grown apples for pest control chemicals used in their production, 1978-86. Food Addit Contam 6(2):227-234
16. Gabaldon JA, Cascales JM, Morias S, Maquieira A, Puchades R (2003) Determination of atrazine and carbaryl pesticide residues in vegetable samples using a multianalyte dipstick immunoassay format. Food Addit Contam 20(8):707-715
17. Gosselin NH, Bouchard M, Brunet RC, Dumoulin MJ, Carrier G (2005) Toxicokinetic modeling of parathion and its metabolites in humans for the determination of biological reference values. Toxicol Mech Methods 15(1):33-52
18. Greenblatt DJ, Ransil BJ, Harmatz JS, Smith TW, Duhme DW, Kosh-Weser J (1976) Variability of 24-hour urinary creatinine excretion by normal subjects. J Clin Pharmacol 16:321-328
19. Jellinek, Schwartz and Connolly, Inc. (2000) The effects and pharmacological disposition of a single oral dose of malathion administered to human volunteers. Unpublished report, CHA Doc. No.: 299 FYF Amdt-4, Cheminova, Lemvig, Denmark. Submitted to EPA on 5/17/00, MRID 45125601
20. Klaassen CD, Watkins JB (1994) Mechanisms of bile formation, hepatic uptake, and biliary excretion. Pharmacol Rev 36:1-67
21. Knaak JB, Tallant MJ, Kozbelt SJ, Sullivan LJ (1965) The metabolism of carbaryl in the rat, guinea pig and man. J Agric Food Chem 13(6):537-543
22. Knaak JB, Tallant MJ, Kozbelt SJ, Sullivan LJ (1968) The metabolism of carbaryl in man, monkey, pig, and sheep. J Agric Food Chem 16(3):465-470
23. Knaak JB, Yee K, Ackerman CR, Zweig G, Fry DM, Wilson BW (1984) Percutaneous absorption and dermal dose-cholinesterase response studies with parathion and carbaryl in the rat. Toxicol Appl Pharmacol 76(2):252-263
24. Lander F, Pike E, Hinke K, Brock A, Nielsen JB (1992) Anti-cholinesterase agents uptake during cultivation of greenhouse flowers. Arch Environ Contam Toxicol 22:159-162
25. Larsen K-O, Hanel HK (1982) Effect of exposure to organophosphorus compounds on cholinesterase in workers removing poisonous depots. Scand J Work Environ Health 8:222-228
26. Maibach HI, Feldmann RJ, Milby TH, Serat WF (1971) Regional variation in percutaneous penetration in man: Pesticides. Arch Environ Health 23:208-211
27. May DG, Naukam RJ, Kambam JR, Branch RA (1992) Cimetidine-carbaryl interaction in humans: Evidence for an active metabolite of carbaryl. J Pharmacol Exp Ther 262(3):1057-1061
28. Meeker JD, Barr DB, Serdar B, Rappaport SM, Hauser R (2006) Utility of urinary 1-naphthol and 2-naphthol levels to assess environmental carbaryl and naphthalene exposure in an epidemiology study. J Expo Sci Environ Epidemiol. Online publication May 2006
29. Ministère de l'Environnement du Québec (2002) Répertoire des principaux pesticides utilisés au Québec. Les Publications du Québec, Quebec
30. Nolan RJ, Rick DL, Freshour NL, Saunders JH (1984) Chlorpyrifos: pharmacokinetics in human volunteers. Toxicol Appl Pharmacol 73:8-15
31. Preuss R, Angerer J, Drexler H (2003) Naphthalene - an environmental and occupational toxicant. Int Arch Occup Environ Health 76(8):556-576
32. Preuss R, Koch HM, Wilhelm M, Pischetsrieder M, Angerer J (2004) Pilot study on the naphthalene exposure of German adults and children by means of urinary 1- and 2-naphthol levels. Int J Hyg Environ Health 207(5):441-445
33. Richter ED, Chuwers P, Levy Y, Gordon M, Grauer F, Marzouk J, Levy S, Barron S, Gruener N (1992) Health effects from exposure to organophosphate pesticides in workers and residents in Israel. Isr J Med Sci 28:584-598
34. Samuel O, St-Laurent L, Dumas P, Langlois E, Gingras G (2002) Pesticides en milieu serricole - Caractérisation de l'exposition des travailleurs et évaluation des délais de réentrée. Report no. R315. Institut de recherche Robert-Sauvé en santé et sécurité au travail (IRSST), Quebec, Canada
35. Smith RL (1973) The excretory function of bile. The elimination of drugs and toxic substances in bile. Chapman and Hall, London
36. Wills JH, Jameson E, Coulston F (1968) Effects of oral doses of carbaryl on man. Clin Toxicol 1(3):265-271