메뉴 건너뛰기




Volumn 376, Issue , 2007, Pages 109-121

Linkage disequilibrium maps and disease-association mapping

(1)  Maniatis, Nikolas a  

a NONE

Author keywords

Association mapping; CYP2D6; LDU; Linkage disequilibrium; Single SNPs

Indexed keywords

ARTICLE; CHROMOSOME MAP; GENE LINKAGE DISEQUILIBRIUM; GENETIC PREDISPOSITION; GENETICS; HAPLOTYPE; HUMAN; METHODOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 36549008071     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1385/1-59745-389-7:109     Document Type: Article
Times cited : (9)

References (26)
  • 1
    • 0037373275 scopus 로고    scopus 로고
    • Discovering genotypes underlying human phenotypes: Past successes for mendelian disease, future approaches for complex disease
    • Botstein, D. and Risch, N. (2003) Discovering genotypes underlying human phenotypes: past successes for mendelian disease, future approaches for complex disease. Nat. Genet. 33, 228-237.
    • (2003) Nat. Genet , vol.33 , pp. 228-237
    • Botstein, D.1    Risch, N.2
  • 2
    • 0037133218 scopus 로고    scopus 로고
    • The first linkage diseqilibrium (LD) maps: Delineation of hot and cold blocks by diplotype analysis
    • Maniatis, N., Collins, A., Xu, C. F., et al. (2002) The first linkage diseqilibrium (LD) maps: delineation of hot and cold blocks by diplotype analysis. Proc. Natl. Acad. Sci. USA 99, 2228-2233.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 2228-2233
    • Maniatis, N.1    Collins, A.2    Xu, C.F.3
  • 3
    • 0032539537 scopus 로고    scopus 로고
    • Mapping a disease locus by allelic association
    • Collins, A. and Morton, N. E. (1998) Mapping a disease locus by allelic association. Proc. Natl. Acad. Sci. USA 95, 1741-1745.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1741-1745
    • Collins, A.1    Morton, N.E.2
  • 6
    • 20444489447 scopus 로고    scopus 로고
    • Applications and extensions of Malecot's work in human genetics
    • Slatkin, M. and Veuille, M, eds, Oxford University Press, Oxford, UK
    • Morton, N. E. (2002) Applications and extensions of Malecot's work in human genetics. In: Modern Developments in Theoretical Population Genetics, (Slatkin, M. and Veuille, M., eds.), Oxford University Press, Oxford, UK.
    • (2002) Modern Developments in Theoretical Population Genetics
    • Morton, N.E.1
  • 8
    • 0034795550 scopus 로고    scopus 로고
    • Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex
    • Jeffreys, A. J., Kauppi, L., and Neumann, R. (2001) Intensely punctate meiotic recombination in the class II region of the major histocompatibility complex. Nat. Genet. 29, 217-222.
    • (2001) Nat. Genet , vol.29 , pp. 217-222
    • Jeffreys, A.J.1    Kauppi, L.2    Neumann, R.3
  • 12
    • 0030586840 scopus 로고    scopus 로고
    • Disequilibrium mapping: Composite likelihood for pairwise disequilibrium
    • Devlin, B., Risch, N., and Roeder, K. (1996) Disequilibrium mapping: composite likelihood for pairwise disequilibrium. Genomics 36, 1-16.
    • (1996) Genomics , vol.36 , pp. 1-16
    • Devlin, B.1    Risch, N.2    Roeder, K.3
  • 13
    • 12344333331 scopus 로고    scopus 로고
    • The optimal measure of linkage disequilibrium reduces error in association mapping of affection status
    • Maniatis, N., Morton, N. E., Gibson, J., Xu, C. F., Hosking, L. K., and Collins, A. (2005) The optimal measure of linkage disequilibrium reduces error in association mapping of affection status. Hum. Mol. Genet. 14, 145-153.
    • (2005) Hum. Mol. Genet , vol.14 , pp. 145-153
    • Maniatis, N.1    Morton, N.E.2    Gibson, J.3    Xu, C.F.4    Hosking, L.K.5    Collins, A.6
  • 14
    • 33749550481 scopus 로고    scopus 로고
    • Effects of single SNPs, haplotypes, and whole Genome LD Maps on accuracy of association mapping
    • Submitted
    • Maniatis, N., Collins, A., and Morton, N. (2006) Effects of single SNPs, haplotypes, and whole Genome LD Maps on accuracy of association mapping. Submitted.
    • (2006)
    • Maniatis, N.1    Collins, A.2    Morton, N.3
  • 15
    • 33749572438 scopus 로고    scopus 로고
    • Refined association mapping of a causal site for a quantitative trait: Weight in the H19-1GF2-INS-TH region
    • in press
    • Zhang, W., Maniatis, N., Rodriguez, S., et al. (2006) Refined association mapping of a causal site for a quantitative trait: weight in the H19-1GF2-INS-TH region. Ann. Hum. Genet., in press.
    • (2006) Ann. Hum. Genet
    • Zhang, W.1    Maniatis, N.2    Rodriguez, S.3
  • 17
    • 18544386662 scopus 로고    scopus 로고
    • Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity
    • Hosking, L. K., Boyd, P. R., Xu, C. F., et al. (2002) Linkage disequilibrium mapping identifies a 390 kb region associated with CYP2D6 poor drug metabolising activity. Pharmacogenomics J. 2, 165-175.
    • (2002) Pharmacogenomics J , vol.2 , pp. 165-175
    • Hosking, L.K.1    Boyd, P.R.2    Xu, C.F.3
  • 18
    • 27544473944 scopus 로고    scopus 로고
    • A comprehensive literature review of haplotyping software and methods for use with unrelated individuals
    • Salem, R. M., Wessel, J., and Schork, N. J. (2005) A comprehensive literature review of haplotyping software and methods for use with unrelated individuals. Hum. Genomics 2, 39-66.
    • (2005) Hum. Genomics , vol.2 , pp. 39-66
    • Salem, R.M.1    Wessel, J.2    Schork, N.J.3
  • 19
    • 0016319012 scopus 로고
    • Estimation of linkage disequilibrium in randomly mating populations
    • Hill, W. G. (1974) Estimation of linkage disequilibrium in randomly mating populations. Heredity 33, 229-239.
    • (1974) Heredity , vol.33 , pp. 229-239
    • Hill, W.G.1
  • 20
    • 18444369013 scopus 로고    scopus 로고
    • The structure of haplotype blocks in the human genome
    • Gabriel, S. B., Schaffner, S. F., Nguyen, H., et al. (2002) The structure of haplotype blocks in the human genome. Science 296, 2225-2229.
    • (2002) Science , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 21
    • 10044254265 scopus 로고    scopus 로고
    • The role of haplotypes in candidate gene studies
    • Clark, A. G. (2004) The role of haplotypes in candidate gene studies. Genet. Epidemiol. 27, 321-333.
    • (2004) Genet. Epidemiol , vol.27 , pp. 321-333
    • Clark, A.G.1
  • 22
    • 23944481324 scopus 로고    scopus 로고
    • Direct analysis of unphased SNP genotype data in populationbased association studies via Bayesian partition modelling of haplotypes
    • Morris, A. P. (2005) Direct analysis of unphased SNP genotype data in populationbased association studies via Bayesian partition modelling of haplotypes. Genet. Epidemiol. 29, 91-107.
    • (2005) Genet. Epidemiol , vol.29 , pp. 91-107
    • Morris, A.P.1
  • 23
    • 13144282294 scopus 로고    scopus 로고
    • Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies
    • Lin, S., Chakravarti, A., and Cutler, D. J. (2004) Exhaustive allelic transmission disequilibrium tests as a new approach to genome-wide association studies. Nat. Genet. 36, 1181-1188.
    • (2004) Nat. Genet , vol.36 , pp. 1181-1188
    • Lin, S.1    Chakravarti, A.2    Cutler, D.J.3
  • 24
    • 20244380171 scopus 로고    scopus 로고
    • Complement factor H polymorphism in age-related macular degeneration
    • Klein, R. J., Zeiss, C., Chew, E. Y., et al. (2005) Complement factor H polymorphism in age-related macular degeneration. Science 308, 385-389.
    • (2005) Science , vol.308 , pp. 385-389
    • Klein, R.J.1    Zeiss, C.2    Chew, E.Y.3
  • 25
    • 0029741063 scopus 로고    scopus 로고
    • The future of genetic studies of complex human diseases
    • Risch, N. and Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science 273, 1516-1517.
    • (1996) Science , vol.273 , pp. 1516-1517
    • Risch, N.1    Merikangas, K.2
  • 26
    • 79959503826 scopus 로고    scopus 로고
    • The International HapMap Project
    • International HapMap Consortium
    • International HapMap Consortium (2003) The International HapMap Project. Nature 426, 789-796.
    • (2003) Nature , vol.426 , pp. 789-796


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.