Neurocognitive effects of nicotine and tobacco in individuals with schizophrenia

Journal of Dual Diagnosis

Volumn 3, Issue 3-4, 2007, Pages 61-77

  Weinberger, Andrea H ^a   Creeden, Cerissa L ^a   Sacco, Kristi A ^a   George, Tony P ^a,b  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

Attention; Cigarette smoking; Cognitive function; Executive function; Nicotine; Schizophrenia; Working memory

Indexed keywords

NICOTINE; NICOTINIC RECEPTOR; PLACEBO; PROTEIN P50;

ACOUSTIC REFLEX; ATTENTION DEFICIT DISORDER; CIGARETTE SMOKING; COGNITIVE DEFECT; DRUG EFFECT; DRUG MEGADOSE; EVOKED AUDITORY RESPONSE; HUMAN; LEARNING DISORDER; MEMORY DISORDER; NICOTINE REPLACEMENT THERAPY; PREPULSE INHIBITION; REVIEW; SCHIZOPHRENIA; SMOKING CESSATION; SMOOTH PURSUIT EYE MOVEMENT; SPATIAL MEMORY; STARTLE REFLEX; TOBACCO; TOBACCO DEPENDENCE; WORKING MEMORY;

EID: 36448994069     PISSN: 15504263     EISSN: 15504271     Source Type: Journal    
DOI: 10.1300/J374v03n03_06     Document Type: Review

References (49)

1. Adler, L. E., Hoffer, L.D., Wiser, A., Freedman, R. (1993). "Normalization of auditory physiology by cigarette smoking in schizophrenic patients." American Journal of Psychiatry 150: 1856-1861.
2. Braff, D. L., Grillon, C., Geyer, M.A. (1992). "Gating and habituation of the startle reflex in schizophrenic patients." Arch. Gen. Psychiatry 49: 206-215.
3. Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences. Hillsdale, N.J., Lawrence Erlbaum Associates.
4. Coyle, J., Kershaw, P. (2001). "Galanthamine, a cholinesterase inhibitor that allosterically modulates nicotinic receptors: Effects on the course of Alzheimer's disease." Biol. Psychiatry 49: 289-299.
5. Dalack, G. W., Healy, D.J., Meador-Woodruff, J.H. (1998). "Nicotine dependence and schizophrenia: Clinical phenomenon and laboratory findings." Am. J. Psychiatry 155: 1490-1501.
6. Depatie, L., Driscoll, G.A., Holahan, A.-L. V., Atkinson, V., Thavundayil, J.X., Ying Kin, N.N., Samarthji, L. (2002). "Nicotine and behavioral markers of risk for schizophrenia: A double-blind, placebo-controlled, cross-over study." Neuropsychopharmacology 27: 1056-1070.
7. Evins, A. E., Deckersbach, T., Cather, C., Fruedenreich, O., Culhane, M.A., Henderson, D.C., Green, M.F., Schoenfeld, D.A., Rigotti, N.A., Goff, D.C. (2005). "Independent effects of tobacco abstinence and bupropion on cognitive function in schizophrenia." Journal of Clinical Psychiatry 66(9): 1184-1190.
8. Freedman, R. (2003). "Schizophrenia." N. Engl. J. Med. 349: 1738-1749.
9. Freedman, R., Coon, H., Myles-Worsley, M., Orr-Urtreger, A., Olincy, A., Davis, A., Polymeropoulos, M., Holik, J., Hopkins, J., Rosenthal, J., Waldo, M.C., Reimherr, F., Wender, P., Yaw, J., Young, D.A., Breese, C.R., Adams, C., Patterson, D., Adler, L.E., Kruglyak, L., Leonard, S., Byerley, W. (1997). "Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus." Proceedings of the National Academy of Sciences of the USA 94(587-592).
10. George, T. P., O'Malley, S.S. (2004). "Current pharmacological treatments for nicotine dependence." Trends Pharmacol. Sci. 25(1): 42-48.
11. George, T. P., Termine, A., Sacco, K.A., Seyal, A.A., Dudas, M.M., Allen, T.M., Vessicchio, J.C., Duncan, E.J. (2006). "Effects of cigarette smoking on prepulse inhibition in schizophrenia: Involvement of nicotinic receptor mechanisms." Schizophr. Res. 87: 307-315.
12. George, T. P., Verrico, C.D., Picciotto, M.R., Roth, R.H. (2000). "Nicotinic modulation of mesoprefrontal dopamine systems: Pharmacologic and neuroanatomic characterization." J. Pharmacol. Exp. Ther. 295(1): 58-66.
13. George, T. P., Verrico, C.D., Roth, R.H. (1998). "Effects of repeated nicotine pretreatment on mesoprefontal dopaminergic and behavioral responses to acute footshock stress." Brain Research 801: 36-49.
14. George, T. P., Vessicchio, J.C., Termine, A., Sahady, D.M., Head, C.A., Pepper, W.T., Kosten, T.R., Wexler, B.E. (2002a). "Effects of smoking abstinence on visuospatial working memory function in schizophrenia." Neuropsychopharmacology 26: 75-85.
15. Grant, B. F., Hasin, D.S., Chou, P., Stinson, F.S., Dawson, D.A. (2004). "Nicotine dependence and psychiatric disorders in the United States." Arch. Gen. Psychiatry 61: 1107-1115.
16. Green, M. F. (1996). "What are the functional consequences of neurocognitive deficits in schizophrenia?" Am. J. Psychiatry 153(3): 321-330.
17. Griffith, J. M., O'Neill, J.E., Petty, F., Garver, D., Young, D., Freedman, R. (1998). "Nicotinic receptor desensitization and sensory gating deficits in schizophrenia." Biological Psychiatry 44: 98-106.
18. Gur, R. E., Cowell, P.E., Latshaw, A., Turetsky, B.I., Grossman, R.I., Arnold, S.E., Bilker, W.B., & Gur, R.C. (2000). "Reduced dorsal and orbital prefrontal gray matter volumes in schizophrenia." Archives of General Psychiatry 57: 761-768.
19. Harris, J. G., Kongs, S., Allensworth, D., Martin, L., Tregellas, J., Sullivan, B., Zerbe, G., Freedman, R. (2004). "Effects of nicotine on cognitive deficits in schizophrenia." Neuropsychopharmacology 29: 1378-1385.
20. Hildebrand, B. E., Panagis, G., Svennson, T.H., Nomikos, G.G. (1999). "Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: Role of nicotinic receptors in the ventral tegmental area." Neuropsychopharmacology 21: 560-574.
21. Hughes, J. R., Hatsukami, D.K., Mitchell, J.E., Dahlgreen, L.A. (1986). "Prevalence of smoking among psychiatric outpatients." American Journal of Psychiatry 143: 993-997.
22. Jacobsen, L. K., D'Souza, D.C., Mencl, W.E., Pugh, K.R., Skudlarski, P., Krystal, J.H. (2004). "Nicotine effects on brain function and functional connectivity in schizophrenia." Biol. Psychiatry 55: 850-858.
23. Kalman, D., S. B. Morrisette et al. (2005). "Co-morbidity of smoking with psychiatric and substance use disorders." American Journal on Addictions 14(2): 106-123.
24. Keefe, R. S. E., Lees Roitman, S.E., Harvey, P.D., Blum, C.S., DuPre, R.L., Prieto, R.M., Davidson, M., Davis, K.L. (1995). "A pen-and-paper human analogue of a monkey prefrontal cortex activation task: Spatial working memory in patients with schizophrenia." Schizophrenia Research 17: 25-33.
25. Kumari, V., Soni, W., Sharma, T. (2001). "Influence of cigarette smoking on prepulse inhibition of the acoustic startle response in schizophrenia." Hum. Psychopharmacol. 16: 321-326.
26. Lasser, K., Boyd, J.W., Woolhander, S., Himmelstein, D.U., McCormick, D., Bor, D.H. (2000). "Smoking and mental illness: a population-based prevalence study." J. Am. Med. Assoc. 284: 2606-2610.
27. Leonard, S., Gault, J., Hopkins, J., Logel, J., Viazon, R., Short, M., Drebing, C., Berger, R., Venn, D., Sirota, P., Zerbe, G., Olincy, A., Ross, R.G., Adler, L.E., Freedman, R. (2002). "Promoter variants in the alpha-7 nicotinic acetylcholine receptor subunit gene are associated with an inhibitory deficit found in schizophrenia." Arch. Gen. Psychiatry. 59: 1085-1096.
28. Levin, E. D., McClernon, F.J., Rezvani, A.H. (2006). "Nicotinic effects on cognitive function: Behavioral characterization, pharmacological specification, and anatomic localization." Psychopharmacology 184(3-4): 523-539.
29. Levin, E. D., Simon, B.B. (1998). "Nicotinic acetylcholine involvement in cognitive function in animals." Psychopharmacology 138: 217-230.
30. Levin, E. D., Wilson, W., Rose, J., McEvoy, J. (1996). "Nicotine-haloperidol interactions and cognitive performance in schizophrenics." Neuropsychopharmacology 15(429-436).
31. Lezak, M. D. (2004). Neuropsychological Assessment. New York, Oxford University Press.
32. Marder, S. R. (2006). "Drug initiatives to improve cognitive function." J Clin Psychiatry 67(suppl 9): 31-35.
33. Newhouse, P. A., Potter, A., Singh, A. (2004). "Effects of nicotinic stimulation on cognitive performance." Curr. Opin. Pharmacol. 4: 36-46.
34. Olincy, A., Harris, J.G., Johnson, L.L., Pender, V., Kongs, S., Allensworth, D., Ellis, J., Zerbe, G.O., Leonard, S., Stevens, K.E., Stevens, J.O., Martin, L., Adler, L.E., Soti, F., Kem, W.R., Freedman, R. (2006). "Proof-of-Concept Trial of an alpha-7 Nicotinic Agonist in Schizophrenia." Arch. Gen. Psychiatry 63: 630-638.
35. Olincy, A., Ross, R.G., Young, D.A., Roath, M., Freedman, R. (1998). "Improvement in smooth pursuit eye movements after cigarette smoking in schizophrenic patients." Neuropsychopharmacology 18: 175-185.
36. Park, S., Holzman, P.S. (1992). "Schizophrenics show spatial working memory deficits." Archives of General Psychiatry 49: 975-982.
37. Parrott, A. C. a. C., D. (1992). "Cigarette smoking and nicotine gum (0, 2 and 4 mg): Effects upon four visual attention tasks." Neuropsychobiology 25: 34-43.
38. Parwani, A., Duncan, E.J., Bartlett, E. et al. (2000). "Impaired prepulse inhibition of acoustic startle in schizophrenia." Biological Psychiatry 47: 662-669.
39. Sacco, K. A., Bannon, K.L., George, T.P. (2004). "Nicotinic receptor mechanisms and cognition in normal states and neuropsychiatric disorders." J. Psychopharmacol. 18(4): 457-474.
40. Sacco, K. A., Termine, A., Seyal, A.A., Dudas, M.M., Vessicchio, J.C, Krishnan-Sarin, S., Jatlow, P.I., Wexler, B.E., George, T.P. (2005). "Effects of cigarette smoking function on spatial working memory and attentional function in schizophrenia: Involvement of nicotinic receptor mechanisms." Archives of General Psychiatry 62: 649-659.
41. Schlaepfer, T. E., Harris, G.J., Tien, A.Y., Peng, L.W., Lee, S., Federman, E.B., Chase, G.A., Barta, P.E., Pearlson, G.D. (1994). "Decreased regional cortical gray matter volume in schizophrenia." Am. J. Psychiatry. 151: 842-848.
42. Sherr, J. D., Myers, C., Avila, M.T., Elliott, A., Blaxton, T.A., Thaker, G.K. (2002). "The effects of nicotine on specific eye tracking measures in schiozphrenia." Biological Psychiatry 52: 721-728.
43. Smith, R. C., Singh, A., Infante, M., Khandat, A., Kloos, A. (2002). "Effects of cigarette smoking and nicotine nasal spray on psychiatric symptoms and cognition in schizophrenia." Neuropsychopharmacology 27: 479-497.
44. Smith, R. C., Warner-Cohen, J., Matute, M., Butler, E., Kelly, E., Vaidhyanathaswamy, S., Khan A. (2006). "Effects of nicotine nasal spray on cognitive function in schizophrenia." Neuropsychopharmacology 31: 637-643.
45. Smith, R. C., Warner-Cohen, J., Matute, M., Butler, E., Kelly, E., Vaidhyanathaswamy, S., Khan, A. (2006). "Effects of nicotine nasal spray on cognitive function in schizophrenia." Neuropsychopharmacology 31: 637-643.
46. Sullivan, E., Lim, K., Mathalon, D., Marsh, L., Beal, D., Harris, D., Hoff, A., Faustman, W., Pfefferbaum, A. (1998). "A profile of cortical gray matter volume deficits characteristic of schizophrenia." Cerebral Cortex 8: 117-124.
47. Swerdlow, N. R., Caine, S.B., Braff, D.L., Geyer, M.A. (1992). "The neural substrates of sensorimotor gating of the startle reflex: A review of recent findings and their implications." J. Psychopharmacol. 6: 176-190.
48. Tamminga, C. A. (2006). "The neurobiology of cognition in schizophrenia." J Clin Psychiatry 67(suppl 9).
49. Vezina, P., Blanc, G., Glowinski, J., Tassin, J.P. (1992). "Nicotine and morphine differentially activate brain dopamine in prefrontalcortical and subcortical terminal fields: effects of acute and repeated injections." JPET 261: 484-490.