Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 860, Issue 1, 2007, Pages 18-25

  Chen, Xiaoyan ^a   Deng, Pan ^a   Dai, Xiaojian ^a   Zhong, Dafang ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Amodiaquine; Ion pair liquid chromatography tandem mass spectrometry; N desethylamodiaquine; Pentafluoropropionic acid; Pharmacokinetics

Indexed keywords

AMODIAQUINE; ATMOSPHERIC PRESSURE CHEMICAL IONIZATION (APCI) INTERFACE; CHROMATOGRAPHIC SEPARATION; N-DESETHYLAMODIAQUINE; PENTAFLUOROPROPIONIC ACID;

BLOOD; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; PHARMACOKINETICS;

ORGANIC COMPOUNDS;

4 AMINOQUINOLINE; ACETONITRILE; AMODIAQUINE; DRUG METABOLITE; HYDROXYCHLOROQUINE; N DESETHYLAMODIAQUIN; PENTAFLUOROPROPIONIC ACID; PROPIONIC ACID; UNCLASSIFIED DRUG;

ARTICLE; BLOOD; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; HUMAN; HUMAN TISSUE; ION PAIR CHROMATOGRAPHY; MASS SPECTROMETRY; MONITORING; NORMAL HUMAN; PRIORITY JOURNAL; REVERSED PHASE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

ACETONITRILES; AMODIAQUINE; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; HUMANS; MALE; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 36348988664     PISSN: 15700232     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jchromb.2007.09.040     Document Type: Article

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