Comparative in vitro and ex vivo activities of selected inhibitors of transthyretin aggregation: Relevance in drug design

Biochemical Journal

Volumn 408, Issue 1, 2007, Pages 131-138

  Cardoso, Isabel ^a   Almeida, Maria Rosário ^a,b   Ferreira, Nelson ^a,b   Arsequell, Gemma ^c   Valencia, Gregorio ^c   Saraiva, Maria João ^a,b  

^a UNIVERSITY OF PORTO   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c DEPARTMENT OF ENVIRONMENTAL CHEMISTRY   (Spain)

Author keywords

Aggregation; Amyloid; Anti amyloidogenic drug; Iododiflunisal; Transthyretin

Indexed keywords

AMYLOIDS; ANTI-AMYLOIDOGENIC DRUGS; IODODIFLUNISAL; TRANSTHYRETIN;

AGGLOMERATION; BIOASSAY; DRUG PRODUCTS; MUTAGENESIS; PHENOLS; RATS;

PROTEINS;

2 [(3,5 DICHLOROPHENYL)AMINO]BENZOIC ACID; 4 (3,5 DIFLUOROPHENYL)BENZOIC ACID; AMYLOID; BENZOXAZOLE; IODINE DERIVATIVE; IODODIFLUNISAL; PREALBUMIN; PROTEIN INHIBITOR; TRIIODOPHENOL; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; CULTURE MEDIUM; DOT HYBRIDIZATION; DRUG DESIGN; EX VIVO STUDY; FIBER; GENETIC TRANSFECTION; IMMUNODETECTION; IN VITRO STUDY; NEURILEMOMA; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN ISOLATION; RAT; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; CELL LINE, TUMOR; DRUG DESIGN; GENE EXPRESSION; HUMANS; MASS SPECTROMETRY; MICROSCOPY, ELECTRON, TRANSMISSION; MUTATION; PREALBUMIN; PROTEIN BINDING; PROTEIN FOLDING; RATS;

RATTUS;

EID: 36348960658     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20070689     Document Type: Article

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