In vivo evaluation of indolyl glyoxamides in the phenotypic sea urchin embryo assay

Chemical Biology and Drug Design

Volumn 70, Issue 6, 2007, Pages 485-490

  Semenova, Marina N ^a   Kiselyov, Alex S ^b   Titov, Ilia Y ^b   Raihstat, Mikhail M ^b   Molodtsov, Maxim ^c,d   Grishchuk, Ekaterina ^e,f   Spiridonov, Ilia ^d,e   Semenov, Victor V ^b,g  

^a KOL TSOV INSTITUTE OF DEVELOPMENTAL BIOLOGY   (Russian Federation)

^b N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^c CENTER FOR THEORETICAL PROBLEMS OF PHYSICOCHEMICAL PHARMACOLOGY   (Russian Federation)

^d NATIONAL RESEARCH CENTER FOR HEMATOLOGY   (Russian Federation)

^e UNIVERSITY OF COLORADO   (United States)

^f INSTITUTE OF GENERAL PATHOLOGY AND PATHOPHYSIOLOGY   (Russian Federation)

^g Chemical Block Ltd   (Cyprus)

Author keywords

Antimitotic agents; Glyoxamide; Phenotypic assay; Sea urchin embryo; Tubulin

Indexed keywords

D 24851; INDOLE; INDOLEAMINE; INDOLYL GLYOXAMIDE; NOCODAZOLE; PROTEIN INHIBITOR; TUBULIN; TUBULIN INHIBITOR; UNCLASSIFIED DRUG; VINBLASTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BEHAVIORAL SCIENCE; BLASTULA; CONTROLLED STUDY; CORRELATION ANALYSIS; DEVELOPMENTAL DISORDER; DEVELOPMENTAL STAGE; DRUG SCREENING; EMBRYO; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MAXIMUM ALLOWABLE CONCENTRATION; MICROTUBULE ASSEMBLY; MITOSIS RATE; NONHUMAN; PHENOTYPIC VARIATION; PRIORITY JOURNAL; SEA URCHIN; SWIMMING; ZYGOTE;

ACETAMIDES; ANIMALS; BLASTULA; CATTLE; DRUG EVALUATION, PRECLINICAL; HUMANS; INDOLES; MITOSIS; MODELS, BIOLOGICAL; PARACENTROTUS; TUBULIN; TUBULIN MODULATORS;

ECHINOIDEA;

EID: 36348942338     PISSN: 17470277     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1747-0285.2007.00591.x     Document Type: Article

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