Intracranial pressure observations in a canine model of acute liver failure supported by a bioartificial liver support system

Artificial Organs

Volumn 31, Issue 11, 2007, Pages 834-839

  Patzer II, John F ^a,b,c   Lopez, Roberto C ^b   Aggarwal, Shushma ^d  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c University of Pittsburgh   (United States)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Acute liver failure; Bioartificial liver; Intracranial pressure

Indexed keywords

AMMONIA; ARTIFICIAL ORGANS;

ACUTE LIVER FAILURE; BIOARTIFICIAL LIVER; BIOARTIFICIAL LIVER SUPPORT SYSTEM; CANINE MODELS; COMMON FEATURES; FAILURE MODELLING; GROUP-BASED; INTRACRANIAL PRESSURE; RETROSPECTIVE ANALYSIS; SYSTEMS SUPPORT;

ANIMALS;

GALACTOSAMINE; LACTIC ACID;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOARTIFICIAL LIVER; BLOOD CHEMISTRY; CONTROLLED STUDY; HUMAN; INTRACRANIAL PRESSURE; LINEAR REGRESSION ANALYSIS; LIVER FAILURE; MEDICAL CARE; METABOLIC ACIDOSIS; NONHUMAN; NONPARAMETRIC TEST; PRIORITY JOURNAL; RETROSPECTIVE STUDY;

ANIMALIA;

EID: 36249005488     PISSN: 0160564X     EISSN: 15251594     Source Type: Journal    
DOI: 10.1111/j.1525-1594.2007.00476.x     Document Type: Article

References (30)

1. Jalan R, Williams R. The inflammatory basis of intracranial hypertension in acute liver failure [comment J Hepatol 2001 34 : 940 2.
2. Williams R, Gimson AE. Intensive liver care and management of acute hepatic failure. Dig Dis Sci 1991 36 : 820 6.
3. Mas A, Rodes J. Fulminant hepatic failure [comment Lancet 1997 349 : 1081 5.
4. Donovan JP, Schafer DF, Shaw BW Jr., Sorrell, MF. Cerebral oedema and increased intracranial pressure in chronic liver disease. Lancet 1998 351 : 719 21.
5. Sorkine P, Ben Abraham R, Szold O, et al. Role of the molecular adsorbent recycling system (MARS) in the treatment of patients with acute exacerbation of chronic liver failure. Crit Care Med 2001 29 : 1332 6.
6. Frerichs FT. A Clinical Treatise on Diseases of the Liver, Volume 1. London, England : The New Sydenham Society, 1860 193 246.
7. Jones EA, Weissenborn K. Neurology and the liver. J Neurol Neurosurg Psychiatry 1997 63 : 279 93.
8. Nencki M, Pawlow JP, Saleski J. Ueber den ammoniakgehalt des blutes und der organe und die harnstoffbildung bei den saugethieren. Archiv Fuer Experimentelle Pathologie und Pharmakologie 1896 37 : 26 51.
9. Eck NV. Ligature of the portal vein. Voen Medical Journal St. Petersburgh (Russ) 1877 130 : 1 2.
10. Clemmesen JO, Larsen FS, Kondrup J, Hansen BA, Ott P. Cerebral herniation in patients with acute liver failure is correlated with arterial ammonia concentration. Hepatology 1999 29 : 648 53.
11. Desjardins P, Belanger M, Butterworth RF. Alterations in expression of genes coding for key astrocytic proteins in acute liver failure. J Neurosci Res 2001 66 : 967 71.
12. Jalan R, Shawcross D, Davies N. The molecular pathogenesis of hepatic encephalopathy. Int J Biochem Cell Biol 2003 35 : 1175 81.
13. Hazell AS, Butterworth RF. Hepatic encephalopathy: an update of pathophysiologic mechanisms. Proc Soc Exp Biol Med 1999 222 : 99 112.
14. Weber FL Jr. Lactulose and combination therapy of hepatic encephalopathy: the role of the intestinal microflora. Dig Dis 1996 14 (Suppl 1 53 63.
15. Watanabe A, Sakai T, Sato S, et al. Clinical efficacy of lactulose in cirrhotic patients with and without subclinical hepatic encephalopathy. Hepatology 1997 26 : 1410 4.
16. Blei AT. Diagnosis and treatment of hepatic encephalopathy. Balliere's Best Pract Res Clin Gastroenterol 2000 14 : 959 74.
17. Wendon JA, Harrison PM, Keays R, Williams R. Cerebral blood flow and metabolism in fulminant liver failure. Hepatology 1994 19 : 1407 13.
18. Jalan R, Davies NA, Damink SW. Hypothermia for the management of intracranial hypertension in acute liver failure. Metab Brain Dis 2002 17 : 437 44.
19. Chatauret N, Rose C, Butterworth RF. Mild hypothermia in the prevention of brain edema in acute liver failure: mechanisms and clinical prospects. Metab Brain Dis 2002 17 : 445 51.
20. Patzer JF, Mazariegos GV, Lopez R. Preclinical evaluation of the Excorp Medical, Inc, bioartificial liver support system. J Am Coll Surg 2002 195 : 299 310.
21. Patzer JF 2nd., Block GD, Khanna A, et al. d-galactosamine based canine acute liver failure model. Hepatobiliary Pancreat Dis Int 2002 1 : 354 67.
22. Patzer JF, Mazariegos GV, Lopez R, et al. Novel bioartificial liver support system: preclinical evaluation. Ann N Y Acad Sci 1999 875 : 340 52.
23. Mazariegos GV, Kramer DJ, Lopez RC, et al. Safety observations in phase I clinical evaluation of the Excorp Medical bioartificial liver support system after the first four patients. ASAIO J 2001 47 : 471 5.
24. Mazariegos GV, Patzer JF, Lopez RC, et al. First clinical use of a novel bioartificial liver support system (BLSS). Am J Transplant 2002 2 : 260 6.
25. Patzer JF, Campbell B, Miller R. Plasma versus whole blood perfusion in a bioartificial liver assist device. ASAIO J 2002 48 : 226 33.
26. Sielaff TD, Hu MY, Rollins MD, et al. An anesthetized model of lethal canine galactosamine fulminant hepatic failure. Hepatology 1995 21 : 796 804.
27. Vogels BA, van Steynen B, Maas MA, Jorning GG, Chamuleau RA. The effects of ammonia and portal-systemic shunting on brain metabolism, neurotransmission and intracranial hypertension in hyperammonaemia-induced encephalopathy. J Hepatol 1997 26 : 387 95.
28. Kundra A, Jain A, Banga A, Bajaj G, Kar P. Evaluation of plasma ammonia levels in patients with acute liver failure and chronic liver disease and its correlation with the severity of hepatic encephalopathy and clinical features of raised intracranial tension. Clin Biochem 2005 38 : 696 9.
29. Blei AT, Larsen FS. Pathophysiology of cerebral edema in fulminant hepatic failure. J Hepatol 1999 31 : 771 6.
30. Tofteng F, Hauerberg J, Hansen BA, Pedersen CB, Jorgensen L, Larsen FS. Persistent arterial hyperammonemia increases the concentration of glutamine and alanine in the brain and correlates with intracranial pressure in patients with fulminant hepatic failure. J Cereb Blood Flow Metab 2006 26 : 21 7.