Validation of respiratory safety pharmacology models: Conscious and anesthetized beagle dogs

Journal of Pharmacological and Toxicological Methods

Volumn 57, Issue 1, 2008, Pages 52-60

  Authier, Simon ^a,b   Legaspi, Margarita ^a,b   Gauvin, Dominique ^b   Chaurand, Fernando ^a   Fournier, Sebastien ^a   Troncy, Eric ^b  

^a LAB Research Inc   (Canada)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

Dogs; Methods; Pharmacology; Pre clinical; Respiratory; Safety; Validation

Indexed keywords

LIDOCAINE; METHACHOLINE; OXYGEN; PROPOFOL; REMIFENTANIL; SALBUTAMOL; SODIUM CHLORIDE; TETRAGASTRIN;

ANESTHESIA MECHANISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERIAL GAS; ARTICLE; BREATHING RATE; CONSCIOUSNESS; CONTROLLED STUDY; DOG; DRUG SAFETY; DRUG SENSITIVITY; FEMALE; HYPOXIA; LUNG COMPLIANCE; LUNG MINUTE VOLUME; MALE; MONITORING; NONHUMAN; OXYGEN SATURATION; RESPIRATORY SYSTEM; TIDAL VOLUME; VALIDATION STUDY;

ALBUTEROL; ANESTHESIA; ANIMALS; BRONCHOCONSTRICTOR AGENTS; BRONCHODILATOR AGENTS; DOGS; DRUG EVALUATION, PRECLINICAL; FEMALE; HYPNOTICS AND SEDATIVES; MALE; METHACHOLINE CHLORIDE; PHARMACEUTICAL PREPARATIONS; PIPERIDINES; REPRODUCIBILITY OF RESULTS; RESPIRATION; RESPIRATORY FUNCTION TESTS; RESPIRATORY INSUFFICIENCY; TETRAGASTRIN; TIME FACTORS;

ANIMALIA; CANIS FAMILIARIS;

EID: 36248984336     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vascn.2007.08.001     Document Type: Article

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