Toxicity studies with pure trans-capsaicin delivered to dogs via intravenous administration

Regulatory Toxicology and Pharmacology

Volumn 43, Issue 1, 2005, Pages 66-75

  Chanda, Sanjay ^a   Mould, Andrew ^b   Esmail, Ashiq ^c   Bley, Keith ^a  

^a NeurogesX Inc   (United States)

^b 206 Carnegie Center   (United States)

^c UK   (United Kingdom)

Author keywords

Bradycardia; Capsaicin; Cardiovascular effect; Dog; Hypotension; Respiratory effect; Tachycardia; Target organ toxicity

Indexed keywords

CAPSAICIN;

ACUTE TOXICITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRADYCARDIA; CARDIOTOXICITY; CONTROLLED STUDY; DOG; DRUG MEGADOSE; DRUG PURITY; FEMALE; HEART MUSCLE POTENTIAL; HYPERTENSION; HYPOTENSION; LUNG TOXICITY; MALE; NONHUMAN; PEPPER; PRIORITY JOURNAL; TACHYCARDIA; TARGET ORGAN; TIME SERIES ANALYSIS;

ANIMALS; BLOOD CELL COUNT; CAPSAICIN; CARDIOVASCULAR SYSTEM; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYMES; FEMALE; HYPERTENSION; INJECTIONS, INTRAVENOUS; MALE; RESPIRATORY SYSTEM; SEX FACTORS; STEREOISOMERISM; TACHYCARDIA; TIME FACTORS;

CANIS FAMILIARIS; CAPSICUM FRUTESCENS;

EID: 24644467284     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2005.06.003     Document Type: Article

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