A novel method for chronic measurement of respiratory function in the conscious monkey

Journal of Pharmacological and Toxicological Methods

Volumn 46, Issue 1, 2001, Pages 13-20

  Murphy, Dennis J ^a   Renninger, Jonathan P ^a   Coatney, Robert W ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Conscious monkey; Lung function; Macaca fascicularis; Methods; Pleural pressure; Respiratory; Ventilatory function

Indexed keywords

BRONCHOCONSTRICTING AGENT; METHACHOLINE; MORPHINE;

ABDOMINAL WALL; ANIMAL EXPERIMENT; ARTICLE; BREATHING PATTERN; CATHETER; CONTROLLED STUDY; DIAPHRAGM; DRUG EFFECT; ESOPHAGUS; IMPLANTATION; LAPAROTOMY; LUNG; LUNG PRESSURE; MALE; MEASUREMENT; MONKEY; NONHUMAN; PLETHYSMOGRAPHY; RESPIRATORY AIRFLOW; RESPIRATORY FUNCTION; TELEMETRY; THORAX PRESSURE;

AIRWAY RESISTANCE; ANIMALS; BRONCHOCONSTRICTOR AGENTS; CONSCIOUSNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; LUNG; MACACA FASCICULARIS; MALE; METHACHOLINE CHLORIDE; MORPHINE; PLETHYSMOGRAPHY; PULMONARY VENTILATION; RESPIRATORY FUNCTION TESTS; TELEMETRY; TIDAL VOLUME;

ANIMALIA; MACACA; MACACA FASCICULARIS; PHOCIDAE; PRIMATES;

EID: 0035726148     PISSN: 10568719     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8719(01)00159-9     Document Type: Article

References (21)

1. Use of a head dome system to compare i.v. methacholine-induced bronchoconstriction in conscious vs anesthetized rhesus monkeys
2. Mechanics of respiration in unanesthetized guinea pigs
3. Comparative control of respiration
4. Interpretation of new techniques used in the determination of pulmonary function in rodents
5. Pulmonary function testing in the rabbit
6. The relevance to humans of animal models for inhalation studies of cancer in the nose and upper airways
7. Pulmonary mechanics in normal rats
8. Pulmonary mechanics in conscious Fisher 344 rats: Multiple evaluations using nonsurgical techniques
9. Airway dilation and constriction in spontaneously breathing guinea pigs
10. The cholecystokinin receptor antagonist devazepide enhances morphine-induced analgesia but not morphine-induced respiratory depression in the squirrel monkey
11. Comparison of esophageal and pleural pressures in the anesthetized dog
12. The effect of nasal and nasopharyngeal irritation on airway resistance in man
13. Respiratory mechanics in normal hamsters
14. Elevation gradient of intrathoracic pressure
15. Lung volume and pleural pressure in the anesthetized hamster
16. Safety pharmacology of the respiratory system: Techniques and study design
17. A novel method for chronic measurement of pleural pressure in conscious rats
18. Measurement of ventilatory mechanics in the rat
19. A novel method to assess airway function parameters in chronically instrumented, unrestrained guinea-pigs
20. Dynamic respiratory mechanics in intact anesthetized hamsters
21. Respiratory and cardiovascular effects of prostaglandins in the conscious guinea pig