-
1
-
-
0042305479
-
Alpha-1-acid glyco-protein binds to imatinib (ST1571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients
-
Gambacorti-Passerini C, Zucchetti M, Russo D, et al. Alpha-1-acid glyco-protein binds to imatinib (ST1571) and substantially alters its pharmacokinetics in chronic myeloid leukemia patients. Clin Cancer Res. 2003;9:625-32.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 625-632
-
-
Gambacorti-Passerini, C.1
Zucchetti, M.2
Russo, D.3
-
2
-
-
9444282642
-
Active transport of imatinib into and out of cells: Implications for drug resistance
-
Thomas J, Wang L, Clark RE, Pirmohamed M. Active transport of imatinib into and out of cells: implications for drug resistance. Blood. 2004;104:3739-45.
-
(2004)
Blood
, vol.104
, pp. 3739-3745
-
-
Thomas, J.1
Wang, L.2
Clark, R.E.3
Pirmohamed, M.4
-
3
-
-
0035800507
-
Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification
-
Gorre ME, Mohammed M, Ellwood K, et al. Clinical resistance to STI-571 cancer therapy caused by BCR-ABL gene mutation or amplification. Science. 2001;293:876-80.
-
(2001)
Science
, vol.293
, pp. 876-880
-
-
Gorre, M.E.1
Mohammed, M.2
Ellwood, K.3
-
4
-
-
27244437924
-
New targeted approaches in chronic myeloid leukemia
-
Cortes J, Kantarjian H. New targeted approaches in chronic myeloid leukemia. J Clin Oncol. 2005;23:6316-24.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6316-6324
-
-
Cortes, J.1
Kantarjian, H.2
-
5
-
-
34249785800
-
Trough plasma imatinib concentrations are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia
-
Abstract 2141
-
Picard S, Titier K, Etienne G, et al. Trough plasma imatinib concentrations are associated with both cytogenetic and molecular responses to standard-dose imatinib in chronic myeloid leukemia. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 2141.
-
(2006)
Blood (ASH Annual Meeting Abstracts)
, vol.108
-
-
Picard, S.1
Titier, K.2
Etienne, G.3
-
6
-
-
36249030792
-
-
Larson RA, Druker BJ, Guilhot F, et al. Correlation of pharmacokinetic data with cytogenetic and molecular response in newly diagnosed patients with chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib - an analysis of IRIS study data. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 429.
-
Larson RA, Druker BJ, Guilhot F, et al. Correlation of pharmacokinetic data with cytogenetic and molecular response in newly diagnosed patients with chronic myeloid leukemia in chronic phase (CML-CP) treated with imatinib - an analysis of IRIS study data. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 429.
-
-
-
-
7
-
-
33644523280
-
Management of early stage disease
-
Deininger MWN. Management of early stage disease. Hematology. 2005;2005:174-82.
-
(2005)
Hematology
, vol.2005
, pp. 174-182
-
-
Deininger, M.W.N.1
-
8
-
-
36248960826
-
-
Cortes J, Giles F, Salvado AJ, et al. Molecular responses in newly diagnosed chronic myelocytic leukemia (CML) patients treated with 800 mg imatinib daily: an update from the RIGHT trial study group. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 2149.
-
Cortes J, Giles F, Salvado AJ, et al. Molecular responses in newly diagnosed chronic myelocytic leukemia (CML) patients treated with 800 mg imatinib daily: an update from the RIGHT trial study group. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 2149.
-
-
-
-
10
-
-
36249018628
-
Chronic myelogenous leukemia
-
Available at:, Accessed August 14
-
Besa EC, Woermann U. Chronic myelogenous leukemia, eMedicine. Available at: http://www.emedicine.com/med/topic371.htm. Accessed August 14, 2007.
-
(2007)
eMedicine
-
-
Besa, E.C.1
Woermann, U.2
-
11
-
-
36249018625
-
-
Rosti G, Castagnetti F, Amabile M, et al. Imatinib high dose (800 mg): results of a phase II trial of the GIMEMA (Gruppo Italiano Malattie Ematologiche Deli'Adulto) CML working party in intermediate sokal risk patients and status-of-the-art of an ongoing multinational, prospective randomized trial of imatinib standard dose (400 mg daily) vs high dose (800 mg daily) in high sokal risk patients. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 4776.
-
Rosti G, Castagnetti F, Amabile M, et al. Imatinib high dose (800 mg): results of a phase II trial of the GIMEMA (Gruppo Italiano Malattie Ematologiche Deli'Adulto) CML working party in intermediate sokal risk patients and status-of-the-art of an ongoing multinational, prospective randomized trial of imatinib standard dose (400 mg daily) vs high dose (800 mg daily) in high sokal risk patients. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 4776.
-
-
-
-
12
-
-
0037438467
-
Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia
-
Kantarjian HM, Talpaz M, O'Brien S, et al. Dose escalation of imatinib mesylate can overcome resistance to standard-dose therapy in patients with chronic myelogenous leukemia. Blood. 2003;101:473-75.
-
(2003)
Blood
, vol.101
, pp. 473-475
-
-
Kantarjian, H.M.1
Talpaz, M.2
O'Brien, S.3
-
13
-
-
33745102555
-
Dasatmib in imatinib-resistant Philadelphia chromosome-positive leukemias
-
Talpaz M, Shah NP, Kantarjian H, et al. Dasatmib in imatinib-resistant Philadelphia chromosome-positive leukemias. N Engl J Med. 2006;354:2531-41.
-
(2006)
N Engl J Med
, vol.354
, pp. 2531-2541
-
-
Talpaz, M.1
Shah, N.P.2
Kantarjian, H.3
-
14
-
-
0037085785
-
Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: Results of a phase 2 study
-
Talpaz M, Silver RT, Druker BJ, et al. Imatinib induces durable hematologic and cytogenetic responses in patients with accelerated phase chronic myeloid leukemia: results of a phase 2 study. Blood. 2002;99:1928-37
-
(2002)
Blood
, vol.99
, pp. 1928-1937
-
-
Talpaz, M.1
Silver, R.T.2
Druker, B.J.3
-
15
-
-
0037093092
-
Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: Results of a phase II study
-
Sawyers CL, Hochhaus A, Feldman E, et al. Imatinib induces hematologic and cytogenetic responses in patients with chronic myelogenous leukemia in myeloid blast crisis: results of a phase II study. Blood. 2002;99:3530-39.
-
(2002)
Blood
, vol.99
, pp. 3530-3539
-
-
Sawyers, C.L.1
Hochhaus, A.2
Feldman, E.3
-
16
-
-
36249027843
-
-
Baccarani M, Kantarjian HM, Apperley JF, et al. Efficacy of dasatinib (SPRYCEL®) in patients (pts) with chronic phase chronic myelogenous leukemia (CP-CML) resistant to or intolerant of imatinib: updated results of the CA180013 'START-C' phase II study. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 164.
-
Baccarani M, Kantarjian HM, Apperley JF, et al. Efficacy of dasatinib (SPRYCEL®) in patients (pts) with chronic phase chronic myelogenous leukemia (CP-CML) resistant to or intolerant of imatinib: updated results of the CA180013 'START-C' phase II study. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 164.
-
-
-
-
17
-
-
36248978820
-
-
Shah N, Pasquini R, Rousselot P, et al. Dasatinib (SPRYCEL®) vs escalated dose of imatinib (im) in patients (pts) with chronic phase chronic myeloid leukemia (CP-CML) resistant to imatinib: results of the CA180-017 START-R randomized study. Blood (ASH Annual Meeting Abstracts). 2006;108: Abstract 167.
-
Shah N, Pasquini R, Rousselot P, et al. Dasatinib (SPRYCEL®) vs escalated dose of imatinib (im) in patients (pts) with chronic phase chronic myeloid leukemia (CP-CML) resistant to imatinib: results of the CA180-017 START-R randomized study. Blood (ASH Annual Meeting Abstracts). 2006;108: Abstract 167.
-
-
-
-
18
-
-
34247248807
-
Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure
-
Kantarjian H, O'Brien S, Talpaz M, et al. Outcome of patients with Philadelphia chromosome-positive chronic myelogenous leukemia post-imatinib mesylate failure. Cancer. 2007;109:1556-60.
-
(2007)
Cancer
, vol.109
, pp. 1556-1560
-
-
Kantarjian, H.1
O'Brien, S.2
Talpaz, M.3
-
19
-
-
36249032234
-
Dasatinib (SPRYCEL®) 50 mg or 70 mg BID versus 100 mg or 140 mg QD in patients with chronic myeloid leukemia in chronic phase (CML-CP) resistant or intolerant to imatinib: Results of the CA180-034 study
-
Abstract 166
-
Hochhaus A, Kim DW, Rousselot P, et al. Dasatinib (SPRYCEL®) 50 mg or 70 mg BID versus 100 mg or 140 mg QD in patients with chronic myeloid leukemia in chronic phase (CML-CP) resistant or intolerant to imatinib: results of the CA180-034 study. Blood (ASH Annual Meeting Abstracts). 206;108:Abstract 166.
-
Blood (ASH Annual Meeting Abstracts)
, vol.206
, pp. 108
-
-
Hochhaus, A.1
Kim, D.W.2
Rousselot, P.3
-
20
-
-
36249005729
-
-
Hehlmann R, Pfirrmann M, Hochhaus A, et al. Randomized comparison of primary allogeneic stem cell transplantation and best available drug treatment in chronic myeloid leukemia. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 427.
-
Hehlmann R, Pfirrmann M, Hochhaus A, et al. Randomized comparison of primary allogeneic stem cell transplantation and best available drug treatment in chronic myeloid leukemia. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 427.
-
-
-
-
21
-
-
36249025028
-
-
Mahon F-X, Huguet F, Etienne G, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission: an update follow up. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 2154.
-
Mahon F-X, Huguet F, Etienne G, et al. Imatinib mesylate discontinuation in patients with chronic myelogenous leukemia in complete molecular remission: an update follow up. Blood (ASH Annual Meeting Abstracts). 2006;108:Abstract 2154.
-
-
-
-
22
-
-
34548620214
-
Pharmacy benefit spending on oral chemotherapy drugs
-
Available at
-
Curtiss FR. Pharmacy benefit spending on oral chemotherapy drugs. J Manag Care Pharm. 2006;12:570-77. Available at: www.amcp.org/data/jmcp/ contemporary_subjects_570_577.pdf.
-
(2006)
J Manag Care Pharm
, vol.12
, pp. 570-577
-
-
Curtiss, F.R.1
-
23
-
-
11844278529
-
Cost-utility analysis of imatinib mesylate for the treatment of chronic myelogenous leukemia in the chronic phase
-
Warren E, Ward S, Gordois A, Scuffham P. Cost-utility analysis of imatinib mesylate for the treatment of chronic myelogenous leukemia in the chronic phase. Clin Ther. 2004;26:1924-33.
-
(2004)
Clin Ther
, vol.26
, pp. 1924-1933
-
-
Warren, E.1
Ward, S.2
Gordois, A.3
Scuffham, P.4
-
24
-
-
22244468056
-
Cost effectiveness of imatinib compared with interferon-alpha or hydroxycarbamide for first-line treatment of chronic myeloid leukaemia
-
Dalziel K, Round A, Garside R, Stein K. Cost effectiveness of imatinib compared with interferon-alpha or hydroxycarbamide for first-line treatment of chronic myeloid leukaemia. Pharmacoeconomics. 2005;23:515-26.
-
(2005)
Pharmacoeconomics
, vol.23
, pp. 515-526
-
-
Dalziel, K.1
Round, A.2
Garside, R.3
Stein, K.4
-
25
-
-
8844262900
-
Cost-effectiveness of imatinib versus interferon-alpha plus low-dose cytarabine for patients with newly diagnosed chronic-phase chronic myeloid leukemia
-
Reed SD, Anstrom KJ, Ludmer JA, et al. Cost-effectiveness of imatinib versus interferon-alpha plus low-dose cytarabine for patients with newly diagnosed chronic-phase chronic myeloid leukemia. Cancer. 2004;101:2574-83.
-
(2004)
Cancer
, vol.101
, pp. 2574-2583
-
-
Reed, S.D.1
Anstrom, K.J.2
Ludmer, J.A.3
-
26
-
-
14544299196
-
Cost-efficacy of imatinib versus allogeneic bone marrow transplantation with a matched unrelated donor in the treatment of chronic myelogenous leukemia: A decision-analytic approach
-
Skrepnek GH, Ballard EE. Cost-efficacy of imatinib versus allogeneic bone marrow transplantation with a matched unrelated donor in the treatment of chronic myelogenous leukemia: a decision-analytic approach. Pharmacotherapy. 2005;25:325-34.
-
(2005)
Pharmacotherapy
, vol.25
, pp. 325-334
-
-
Skrepnek, G.H.1
Ballard, E.E.2
|