Direct observation of a transient tyrosine radical competent for initiating turnover in a photochemical ribonucleotide reductase

Journal of the American Chemical Society

Volumn 129, Issue 45, 2007, Pages 13828-13830

  Reece, Steven Y ^a   Seyedsayamdost, Mohammad R ^a   Stubbe, JoAnne ^a   Nocera, Daniel G ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; BACTERIAL ENZYME; RADICAL; RIBONUCLEOTIDE REDUCTASE; SYNTHETIC PEPTIDE; TYROSINE;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; COMPETITIVE INHIBITION; ELECTRON TRANSPORT; ENZYME ACTIVITY; ENZYME SUBSTRATE; ESCHERICHIA COLI; NONHUMAN; PEPTIDE SYNTHESIS; PHOTOCHEMISTRY; PHOTOLYSIS; PROTON COUPLED ELECTRON TRANSFER; SIGNAL NOISE RATIO; SPECTROPHOTOMETRY;

BINDING SITES; ESCHERICHIA COLI; FREE RADICALS; LIGHT; MOLECULAR STRUCTURE; ORGANOMETALLIC COMPOUNDS; PHOTOCHEMISTRY; PROTEIN STRUCTURE, TERTIARY; RHENIUM; RIBONUCLEOTIDE REDUCTASES; TYROSINE;

EID: 36148975297     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja074452o     Document Type: Article

References (19)

1. 3CN; RNR, class I E. coli ribonucleotide reductase; TA, transient absorption; Tris, tris-(hydroxymethyl)aminomethane.
2. Reece, S. Y.; Hodgkiss, J. M.; Stubbe, J.; Nocera, D. G. Philos. Trans. R. Soc. B 2006, 361, 1351.
3. Stubbe, J.; Nocera, D. G.; Yee, C. S.; Chang, M. C. Y. Chem. Rev. 2003, 103, 2167.
4. Jordan, A.; Reichard, P. Annu. Rev. Biochem. 1998, 67, 71.
5. Uhlin, U.; Eklund, H. Nature 1994, 370, 533.
6. Eriksson, M.; Uhlin, U.; Ramaswamy, S.; Ekberg, M.; Regnström, K.; Sjöberg, B. M.; Eklund, H. Structure 1997, 5, 1077.
7. Bennati, M.; Robblee, J. H.; Mugnaini, V.; Stubbe, J.; Freed, J. H.; Borbat, P. J. Am. Chem. Soc. 2005, 127, 15014.
8. Chang, M. C. Y.; Yee, C. S.; Stubbe, J.; Nocera, D. G. Proc. Nat. Acad. Sci. U.S.A. 2004, 101, 6882.
9. Reece, S. Y.; Seyedsayamdost, M. R.; Stubbe, J.; Nocera, D. G. J. Am. Chem. Soc. 2007, 129, 8500.
10. Reece, S. Y.; Nocera, D. G. J. Am. Chem. Soc. 2005, 127, 9448.
11. Seyedsaymdost, M. R.; Reece, S. Y.; Nocera, D. G.; Stubbe, J. J. Am. Chem. Soc. 2006, 128, 1569.
12. Reece, S. Y.; Seyedsayamdost, M. R.; Stubbe, J.; Nocera, D. G. J. Am. Chem. Soc. 2006, 125, 13654.
13. Climent, I.; Sjöberg, B.-M.; Huang, C. Y. Biochemistry 1991, 30, 5164.
14. Chang, M. C. Y.; Yee, C. S.; Stubbe, J.; Nocera, D. G. Proc. Natl. Acad. Sci. U.S.A. 2004, 101, 6882.
15. Seyedsaymdost, M. R.; Yee, C. S.; Reece, S. Y.; Nocera, D. G.; Stubbe, J. J. Am. Chem. Soc. 2006, 128, 1562.
16. Erikson, H. K. Biochemistry 2001, 40, 9631.
17. Ge, J.; Yu, G.; Ator, M. A.; Stubbe, J. Biochemistry 2003, 42, 10071.
18. Seyedsayamdost, M. R.; Stubbe, J. J. Am. Chem. Soc. 2006, 128, 2522.
19. Seyedsayamdost, M. R.; Stubbe, J. J. Am. Chem. Soc. 2007, 129, 2226.