Nitroaryl-1,4-dihydropyridines as antioxidants against rat liver microsomes oxidation induced by iron/ascorbate, Nitrofurantoin and naphthalene

Toxicology in Vitro

Volumn 21, Issue 8, 2007, Pages 1610-1618

  Letelier, María Eugenia ^a   Entrala, Paz ^a   López Alarcón, Camilo ^b   González Lira, Víctor ^a   Molina Berríos, Alfredo ^a   Cortés Troncoso, Juan ^a   Jara Sandoval, José ^a   Santander, Paola ^a   Núñez Vergara, Luis ^a  

^a UNIVERSITY OF CHILE   (Chile)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

Author keywords

Aryl 1,4 dihydropyridines antioxidant agents; Aryl 1,4 dihydropyridines ROS; Calcium channel antagonist oxidative stress

Indexed keywords

1,4 DIHYDROPYRIDINE DERIVATIVE; 2,6 DIMETHYL 4 (3 NITROPHENYL) 1,4 DIHYDROPYRIDIN 3,5 (2 ISOPROPYL)DICARBOXYLATE; 2,6 DIMETHYL 4 (3 NITROPHENYL) 1,4 DIHYDROPYRIDIN 3,5 ETHYLDICARBOXYLATE; 2,6 DIMETHYL 4 (4 NITROPHENYL) 1,4 DIHYDROPYRIDIN 3,5 (2 ISOPROPYL)DICARBOXYLATE; 2,6 DIMETHYL 4 (4 NITROPHENYL) 1,4 DIHYDROPYRIDIN 3,5 ETHYLDICARBOXYLATE; ANTIOXIDANT; CALCIUM CHANNEL BLOCKING AGENT; COPPER ION; CYTOCHROME P450; FERRIC ION; FERROUS ASCORBATE; N ETHYL 2,6 DIMETHYL 4 (4 NITROPHENYL) 1,4 DIHYDROPYRIDIN 3,5 METHYLDICARBOXYLATE; NAPHTHALENE; NITROFURANTOIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; UNCLASSIFIED DRUG;

AEROBIC METABOLISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG TRANSFORMATION; ENDOPLASMIC RETICULUM; LIPID PEROXIDATION; LIVER MICROSOME METABOLISM; MALE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; RAT;

ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; DIHYDROPYRIDINES; ENZYME ACTIVATION; GLUCURONOSYLTRANSFERASE; LIPID PEROXIDATION; MICROSOMES, LIVER; MOLECULAR STRUCTURE; NADP; NAPHTHALENES; NITROFURANTOIN; OXIDATION-REDUCTION; OXYGEN CONSUMPTION; RATS; SULFHYDRYL COMPOUNDS;

RATTUS;

EID: 36148969342     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.06.001     Document Type: Article

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