Different potencies of dihydropyridine derivatives in blocking T-type but not L-type Ca2+ channels in neuroblastoma-glioma hybrid cells

European Journal of Pharmacology

Volumn 342, Issue 2-3, 1998, Pages 339-345

  Stengel, Wolfgang ^a   Jainz, Monika ^a   Andreas, Klaus ^a  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

Ca2+ channel current; Ca2+ channel, T type; Dihydropyridine derivative; Niguldipine

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; DIHYDROPYRIDINE DERIVATIVE;

ANIMAL CELL; ARTICLE; CALCIUM CONDUCTANCE; CELL CULTURE; DATA ANALYSIS; DRUG EFFICACY; DRUG POTENCY; GLIOMA CELL; HEART MUSCLE CELL; MEMBRANE POTENTIAL; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; POTASSIUM CURRENT; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER; VOLTAGE CLAMP;

ANIMALS; BRAIN NEOPLASMS; CALCIUM CHANNEL BLOCKERS; CELL DIFFERENTIATION; DIHYDROPYRIDINES; GLIOMA; HYBRID CELLS; MEMBRANE POTENTIALS; MICE; NEUROBLASTOMA; RATS; TUMOR CELLS, CULTURED;

EID: 0032567798     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-2999(97)01495-7     Document Type: Article

References (32)

1. Akaike N. T-type calcium channel in mammalian CNS neurons. Comp. Biochem. Physiol. 98C:1991;31-40.
2. Akaike N., Kostyuk P.G., Osipchuk Y.V. Dihydropyridine-sensitive low-threshold calcium channels in isolated rat hypothalamic neurons. J. Physiol. 412:1989;181-195.
3. 1-adrenoceptors. Eur. J. Pharmacol. 172:1989;131-145.
4. Carbone E., Lux H.D. A low voltage-activated, fully inactivating Ca channel in vertebrate sensory neurons. Nature. 310:1984;501-502.
5. 2+ channels in mammalian skeletal muscle cells in culture. Proc. Natl. Acad. Sci. USA. 83:1986;517-521.
6. Connors, B.W., Amitai, Y., 1993. Generation of epileptiform discharge by local circuits of neocortex. In: Schwartzkroin, P.A. (Ed.), Epilepsy. Cambridge University Press, Cambridge, pp. 388-423.
7. Coulter D.A., Huguenard J.R., Prince D.A. Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons. Ann. Neurol. 25:1989;582-593.
8. Coulter D.A., Huguenard J.R., Prince D.A. Differential effects of petit mal anticonvulsants and convulsants on thalamic neurons: Calcium current reduction. Br. J. Pharmacol. 100:1990;800-806.
9. Friedman M.E., Suarez-Kurtz G., Kaczorowski G.J., Katz G.M., Reuben J.P. Two calcium currents in a smooth muscle cell line. Am. J. Physiol. 250:1986;H699-H703.
10. Gasior M., Kaminski R., Brudniak T., Kleinrok Z., Czuczwar S.J. Influence of nicardipine, nimodipine and flunarizine on the anticonvulsant efficacy of antiepileptics against pentylenetetrazol in mice. J. Neural Transm. 103:1996;819-831.
11. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391:1981;85-100.
12. 2+ channel block by dihydropyridines: No modulation by the voltage protocol. Eur. J. Pharmacol. 309:1996;317-321.
13. 2+ channels in smooth muscle. Eur. J. Pharmacol. 252:1994;267-274.
14. Isom L.L., De Jongh K.S., Catterall W.A. Auxiliary subunits of voltage-gated ion channels. Neuron. 12:1994;1183-1194.
15. Jeanmonod D., Magnin M., Morel A. Low-threshold calcium spike bursts in the human thalamus. Brain. 119:1996;363-375.
16. 2+ channels in rat aorta smooth muscle cells in primary culture. Circ. Res. 67:1990;469-480.
17. Llinás R., Jahnsen H. Electrophysiology of mammalian thalamic neurons in vitro. Nature. 297:1982;406-408.
18. Loirand G., Pacaud P., Mironneau C., Mironneau J. Evidence for two distinct calcium channels in rat vascular smooth muscle cells in short-term primary culture. Pflüg. Arch. 407:1986;566-568.
19. 2+ antagonists in electrocortical shock seizures. Epilepsia. 31:1990;68-74.
20. Meyer F.B., Cascino G.D., Whisnant J.P., Sharbrough F.W., Ivnik R.J., Gorman D.A., Windschitl W.L., So E.L., O'Fallon W.M. Nimodipine as an add-on therapy for intractable epilepsy. Mayo Clin. Proc. 70:1995;623-627.
21. Mitra R., Morad M. Two calcium channels in guinea pig ventricular myocytes. Proc. Natl. Acad. Sci. USA. 93:1986;5340-5344.
22. Momiyama T., Ishihara K., Serikawa T., Moritake K., Sasa M. Effect of nicardipine on abnormal excitability of CA3 pyramidal cells in hippocampal slices of spontaneously epileptic rats. Eur. J. Pharmacol. 280:1995;119-123.
23. Richard S., Diochot S., Nargeot J., Baldy-Moulinier M., Valmier J. Inhibition of T-type calcium currents by dihydropyridines in mouse embryonic dorsal root ganglion neurons. Neurosci. Lett. 132:1991;229-234.
24. 2+ channel currents in atrial myocytes. Pflügers Arch. 420:1992;410-412.
25. Stengel W., Jainz M., Andreas K. Sensitivity of L- and T-type calcium currents of neuroblastoma-glioma hybrid cells to selected dihydropyridine derivatives. Naunyn-Schmiedeberg's Arch. Pharmacol. 354:1996;R176.
26. Steriade M.M., Llinás R.R. The functional states of the thalamus and the associated neuronal interplay. Physiol. Rev. 68:1988;649-742.
27. Suzuki S., Kawakami K., Nishimura S., Watanabe Y., Yagi K., Seino M., Miyamoto K. Zonisamide blocks T-type calcium channel in cultured neurons of rat cerebral cortex. Epilepsy Res. 12:1992;21-27.
28. 2+ channels in rat isolated hippocampal CA1 pyramidal neurons. Br. J. Pharmacol. 100:1990;705-710.
29. Tsien R.W., Ellinor P.T., Zhang J.-F., Bezprozvanny I. Molecular biology of calcium channels and structural determinants of key functions. J. Cardiovasc. Pharmacol. 27:1996;S4-S10.
30. Worley J.F. III, Deitmer J.W., Nelson M.T. Single nisoldipine-sensitive calcium channels in smooth muscle cells isolated from rabbit mesenteric artery. Proc. Natl. Acad. Sci. USA. 83:1986;5746-5750.
31. Yatani A., Kunze D.L., Brown A.M. Effects of dihydropyridine calcium channel modulators on cardiac sodium channels. Am. J. Physiol. 254:1988;H140-H147.
32. 2+ channels and their possible counterparts in mammalian CNS neurons. Neuropharmacology. 32:1993;1075-1088.