Synthesis of 1H-imidazo[1,2-b]-1,2,4-triazol-6-amines via multicomponent reaction

Molecular Diversity

Volumn 11, Issue 2, 2007, Pages 73-80

  Huang, Yan ^a   Hu, Xiu Qin ^a   Shen, Da Peng ^a   Chen, Yong Fei ^a   Xu, Peng Fei ^a  

^a LANZHOU UNIVERSITY   (China)

Author keywords

Aminotriazole; Cytotoxic activity; Imidazole 1,2 b 1,2,4 triazole; Multicomponent reactions (MCRs)

Indexed keywords

IMIDAZO[2,1 B]THIAZOLE DERIVATIVE; IMIDAZOLE DERIVATIVE; N (TERT BUTYL) 2 (4 BROMOPHENYL) 5 (4 CHLOROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2 (4 BROMOPHENYL) 5 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2 (4 CHLOROPHENYL) 5 (4 METHOXYPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2 (4 CHLOROPHENYL) 5 (4 NITROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2 (4 CHLOROPHENYL) 5 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2 METHYL 5 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2,5 BIS(4 CHLOROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 2,5 DIPHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (2 CHLOROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (2 CHLOROPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (2 METHOXYPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (2 METHOXYPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (3 CHLOROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (3 CHLOROPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 CHLOROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 CHLOROPHENYL) 2 METHYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 CHLOROPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 METHOXYPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 METHOXYPHENYL) 2 METHYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 METHOXYPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 NITROPHENYL) 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 (4 NITROPHENYL) 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 [4 (DIMETHYLAMINO)PHENYL] 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 [4 (DIMETHYLAMINO)PHENYL] 2 PHENYL 1H IMIDAZO[1,2 B][1,2,4]TRIAZOL 6 AMINE; N (TERT BUTYL) 5 PHENYL 1H IMIDAZO[1,2 B] 1,2,4 TRIAZOL 6 AMINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIBACTERIAL ACTIVITY; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; MASS SPECTROMETRY; MULTICOMPONENT REACTION; NITROBLUE TETRAZOLIUM TEST; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; TUMOR GROWTH;

ANIMALS; ANTI-BACTERIAL AGENTS; CATALYSIS; CELLS, CULTURED; DRUG EVALUATION, PRECLINICAL; HUMANS; IMIDAZOLES; MICE; MODELS, BIOLOGICAL; STAPHYLOCOCCUS AUREUS; STRUCTURE-ACTIVITY RELATIONSHIP; TRIAZOLES;

EID: 36148943898     PISSN: 13811991     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11030-007-9059-3     Document Type: Article

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