Quantification of nicotinic acetylcholine receptors in the human brain with PET: Bolus plus infusion administration of 2-[18F]F-A85380

NeuroImage

Volumn 39, Issue 2, 2008, Pages 717-727

  Kimes, Alane S ^a   Chefer, Svetlana I ^a   Matochik, John A ^a   Contoreggi, Carlo S ^a   Vaupel, D Bruce ^a   Stein, Elliot A ^a   Mukhin, Alexey G ^a  

^a NATIONAL INSTITUTE ON DRUG ABUSE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 FLUORO 3 (2 AZETIDINYLMETHOXY)PYRIDINE F 18; NICOTINIC RECEPTOR; RADIOLIGAND; UNCLASSIFIED DRUG;

ADULT; ARTICLE; BRAIN REGION; CLINICAL RESEARCH; DRUG BINDING; DRUG DISTRIBUTION; DRUG INFUSION; DRUG METABOLISM; FEMALE; HUMAN; HUMAN EXPERIMENT; MALE; MEDICAL RESEARCH; METHODOLOGY; NORMAL HUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIOACTIVITY; REPRODUCIBILITY; STEADY STATE; VENOUS BLOOD; VOLUNTEER;

ADULT; AZETIDINES; BRAIN; BRAIN CHEMISTRY; BRAIN MAPPING; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; INFUSIONS, INTRAVENOUS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; POSITRON-EMISSION TOMOGRAPHY; PYRIDINES; RADIOPHARMACEUTICALS; RECEPTORS, NICOTINIC; REPRODUCIBILITY OF RESULTS; SMOKING;

EID: 36148937969     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2007.09.015     Document Type: Article

References (30)

1. Abi-Dargham A., Laruelle M., Seibyl J., Rattner Z., Baldwin R.M., Zoghbi S.S., Zea-Ponce Y., Bremner J.D., Hyde T.M., and Charney D.S. SPECT measurement of benzodiazepine receptors in human brain with iodine-123-iomazenil: kinetic and equilibrium paradigms. J. Nucl. Med. 35 (1994) 228-238
2. 3H]nicotine binding sites in human brain. J. Neurochem. 50 (1988) 1243-1247
3. Bergström M., Grahnén A., and Långström B. Positron emission tomography microdosing: a new concept with application in tracer and early clinical drug development. Eur. J. Clin. Pharmacol. 59 (2003) 357-366
4. 3H]nicotine binding in human postmortem brain. J. Pharmacol. Exp. Ther. 282 (1997) 7-13
5. Brody A.L., Mandelkern M.A., London E.D., Olmstead R.E., Farahi J., Scheibal D., Jou J., Allen V., Tiongson E., Chefer S.I., Koren A.O., and Mukhin A.G. Cigarette smoking saturates brain α4β2 nicotinic acetylcholine receptors. Arch. Gen. Psychiatry 63 (2006) 907-915
6. 18F]cyclofoxy and positron emission tomography. J. Cereb. Blood Flow Metab. 13 (1993) 24-42
7. 18F]FA binding to nicotinic acetylcholine receptors in rhesus monkey brain. Synapse 48 (2003) 25-34
8. Derogatis L.R., Lipman R.S., and Covi L. SCL-90: an outpatient psychiatric rating scale-preliminary report. Psychopharmacol. Bull. 9 (1973) 13-28
9. 18F-Fluoro-A-85380 and PET. J. Nucl. Med. 46 (2005) 240-247
10. Herzog H., Minnerop M., Eschner W., Jessen F., Schütz C., Schmaljohann J., and Wuellner U. Distribution volume of the nicotinic acetylcholine receptor ligand 2-[F-18]F-A-85380: nonsmokers versus smokers. NeuroImage 31 (2006) T156
11. 18F]Fluoro-A-85380, an in vivo tracer for the nicotinic acetylcholine receptors. Nucl. Med. Biol. 25 (1998) 599-603
12. Ichise M., Toyama H., Innis R.B., and Carson R.E. Strategies to improve neuroreceptor parameter estimation by linear regression analysis. J. Cereb. Blood Flow Metab. 22 (2002) 1271-1281
13. 11C]raclopride binding. J. Cereb. Blood Flow Metab. 18 (1998) 941-950
14. Kendziorra K., Meyer P., Wolf H., Barthel H., Hesse S., Seese A., Sorger D., Patt M., Becker G., Schidan A., Gertz H.J., and Sabri O. Cerebral nicotinic acetylcholine receptors in patients with Alzheimer's disease assessed with 2-[18F]F-A85380 PET-correlations to dementia severity. NeuroImage 31 (2006) T39
15. 18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans. FASEB J. 17 (2003) 1331-1333
16. Kimes A.S., Chefer S., Contoreggi C.S., Hall A., Horti A., Vaupel D.B., Pavlova O., Stein E.A., and Mukhin A.G. In vivo quantification of the greater densities of alpha4beta2* nicotinic acetylcholine receptors in smokers compared to non-smokers. NeuroImage 31 (2006) T153
17. Lindstrom J., Anand R., Peng X., Gerzanich V., Wang F., and Li Y. Neuronal nicotinic receptor subtypes. Ann. N. Y. Acad. Sci. 757 (1995) 100-116
18. 11C-methyl]-(-)-cocaine PET studies in human subjects. J. Cereb. Blood Flow Metab. 10 (1990) 740-747
19. Meyer P., Hesse S., Kendziorra K., Becker G., Wegner F., Schildan A., Seese A., Lobsien D., Barthel H., Schwarz J., and Sabri O. Dissociation between striatal alpha4beta2 nicotinic acetylcholine receptors (alpha4beta2) and dopamine transporters (DAT) in Parkinson disease: a 2-[18F]-F-A-85380 PET/[123I]-FP-CIT SPECT study. NeuroImage 31 (2006) T157
20. Meyer P., Kendziorra K., Hesse S., Becker G., Strecker K., Hensel A., Patt M., Seese A., Gertz H.J., Schwarz J., and Sabri O. Nicotinic acetylcholine receptors (alpha4beta2) and their relationship to cognitive and mood symptoms in Parkinson disease: a 2-[18F]-F-A-85380 PET study. NeuroImage 31 (2006) T151
21. Mihailescu S., and Drucker-Colin R. Nicotine, brain nicotinic receptors, and neuropsychiatric disorders. Arch. Med. Res. 31 (2000) 131-144
22. 18F]F-A-85380 PET. Nucl. Med. Biol. 32 (2005) 585-591
23. Picard F., Bruel D., Servent D., Saba W., Fruchart-Gaillard C., Schöllhorn-Peyronneau M.A., Roumenov D., Brodtkorb E., Zuberi S., Gambardella A., Steinborn B., Hufnagel A., Valette H., and Bottlaender M. Alteration of the in vivo nicotinic receptor density in ADNFLE patients: a PET study. Brain 129 (2006) 2047-2060
24. 18F]altanserin-PET and the bolus/infusion approach. J. Cereb. Blood Flow Metab. 23 (2003) 985-996
25. Robins L., Cottler L., Bucholz K., and Compton W. Diagnostic Interview Schedule for DSM-IV (1995), Washington University, St. Louis, MO
26. 18F]F-A-85380 in blood plasma using solid-phase extraction. Nucl. Med. Biol. 34 (2007) 221-228
27. Slifstein M., and Laruelle M. Effects of statistical noise on graphic analysis of PET neuroreceptor studies. J. Nucl. Med. 41 (2000) 2083-2088
28. Staley J.K., Krishnan-Sarin S., Cosgrove K.P., Krantzler E., Frohlich E., Perry E., Dubin J.A., Estok K., Brenner E., Baldwin R.M., Tamagnan G.D., Seibyl J.P., Jatlow P., Picciotto M.R., London E.D., O'Malley S., and van Dyck C.H. Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers. J. Neurosci. 26 (2006) 8707-8714
29. 18F]F-A-85380. NeuroImage 34 (2007) 1352-1362
30. Zachary R.A. Shipley Institute of Living Scale (1986), Western Psychological Services, Los Angeles