Involvement of organic anion transport system in transdermal absorption of flurbiprofen

Journal of Controlled Release

Volumn 124, Issue 1-2, 2007, Pages 60-68

  Ito, Katsuaki ^a   Kato, Yukio ^a   Tsuji, Hiroyuki ^a   Nguyen, Hai Thien ^a   Kubo, Yoshiyuki ^a   Tsuji, Akira ^a  

^a KANAZAWA UNIVERSITY   (Japan)

Author keywords

Carrier mediated transport; NSAIDs; Skin; Transdermal permeation; Transporter

Indexed keywords

CHARACTERIZATION; NEGATIVE IONS; PERMEATION; SKIN;

CARRIER-MEDIATED TRANSPORT; FLURBIPROFEN; MICHAELIS CONSTANTS; NONSTEROIDAL ANTI-INFLAMMATORY DRUGS; TRANSDERMAL PERMEATION; TRANSPORT MECHANISM; USSING-TYPE CHAMBER METHOD;

DRUG DELIVERY;

4 AMINOHIPPURIC ACID; BENZOIC ACID; BROMSULFOPHTHALEIN; BUMETANIDE; FLUORIDE SODIUM; FLURBIPROFEN; FUMARIC ACID; INDOCYANINE GREEN; INDOMETACIN; KETOPROFEN; NONSTEROID ANTIINFLAMMATORY AGENT; ORGANIC ANION TRANSPORTER 2; PHTHALIC ACID; PROBENECID; ROTENONE; SALICYLIC ACID; SUCCINIC ACID; VALPROIC ACID;

ACTIVE TRANSPORT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG PENETRATION; DRUG TRANSPORT; DRUG UPTAKE; EPIDERMIS; ISOTOPE LABELING; LIPOPHILICITY; MALE; MICHAELIS CONSTANT; MOUSE; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; SKIN ABSORPTION; SKIN PENETRATION; TRANSPORT KINETICS;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; FLURBIPROFEN; MALE; MICE; MICE, INBRED HRS; OOCYTES; ORGANIC ANION TRANSPORTERS, SODIUM-INDEPENDENT; SKIN; SKIN ABSORPTION; XENOPUS LAEVIS;

EID: 36049039871     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2007.08.019     Document Type: Article

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