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Volumn 12, Issue 6, 2007, Pages 2207-2211

Three pathogenic determinants in immune nephritis - Anti-glomerular antibody specificity, innate triggers and host genetics

Author keywords

Autoantibody; Immune Nephritis; Kidney; Mouse model; Nephritis; Pathogenic Determinants; Review; SLE; Systemic Lupus Erythromatosus

Indexed keywords

ANTINUCLEAR ANTIBODY; AUTOANTIBODY; DNA; TOLL LIKE RECEPTOR;

EID: 36049020207     PISSN: 27686701     EISSN: 27686698     Source Type: Journal    
DOI: 10.2741/2223     Document Type: Article
Times cited : (4)

References (41)
  • 1
    • 0026814959 scopus 로고
    • Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo
    • D. Vlahakos, M. H. Foster, A. A. Ucci, K. J. Barrett, S. K. Datta, M. P. Madaio: Murine monoclonal anti-DNA antibodies penetrate cells, bind to nuclei, and induce glomerular proliferation and proteinuria in vivo. J Am Soc Nephrol 2(8), 1345-1354 (1992)
    • (1992) J Am Soc Nephrol , vol.2 , Issue.8 , pp. 1345-1354
    • Vlahakos, D.1    Foster, M.H.2    Ucci, A.A.3    Barrett, K.J.4    Datta, S.K.5    Madaio, M.P.6
  • 3
    • 0014167005 scopus 로고
    • The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis
    • R. A. Lerner, R. J. Glassock, F. J. Dixon: The role of anti-glomerular basement membrane antibody in the pathogenesis of human glomerulonephritis. J Exp Med 126(6), 989-1004 (1967)
    • (1967) J Exp Med , vol.126 , Issue.6 , pp. 989-1004
    • Lerner, R.A.1    Glassock, R.J.2    Dixon, F.J.3
  • 4
    • 0021342845 scopus 로고
    • The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-DNA antibodies in NZB/W mice
    • H. Dang, R. J. Harbeck: The in vivo and in vitro glomerular deposition of isolated anti-double-stranded-NA antibodies in NZB/W mice. Clin Immunol Immunopathol 30(2), 265-278 (1984) (Pubitemid 14224509)
    • (1984) Clinical Immunology and Immunopathology , vol.30 , Issue.2 , pp. 265-278
    • Dang, H.1    Harbeck, R.J.2
  • 5
    • 0028074657 scopus 로고
    • Mutational analysis of an autoantibody: Differential binding and pathogenicity
    • DOI 10.1084/jem.180.3.925
    • J. B. Katz, W. Limpanasithikul, B. Diamond: Mutational analysis of an autoantibody: differential binding and pathogenicity. J Exp Med 180(3), 925-932 (1994) (Pubitemid 24256605)
    • (1994) Journal of Experimental Medicine , vol.180 , Issue.3 , pp. 925-932
    • Katz, J.B.1    Limpanasithikul, W.2    Diamond, B.3
  • 7
    • 0028015572 scopus 로고
    • Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo
    • C. Kramers, M. N. Hylkema, M. C. van Bruggen, R. van de Lagemaat, H. B. Dijkman, K. J. Assmann, R. J. Smeenk, J. H. Berden: Anti-nucleosome antibodies complexed to nucleosomal antigens show anti-DNA reactivity and bind to rat glomerular basement membrane in vivo. J Clin Invest 94(2), 568-577 (1994)
    • (1994) J Clin Invest , vol.94 , Issue.2 , pp. 568-577
    • Kramers, C.1    Hylkema, M.N.2    Van Bruggen, M.C.3    Van De Lagemaat, R.4    Dijkman, H.B.5    Assmann, K.J.6    Smeenk, R.J.7    Berden, J.H.8
  • 8
    • 0028232565 scopus 로고
    • Comparison of pathogenic and non-pathogenic murine antibodies to DNA: Antigen binding and structural characteristics
    • K. Ohnishi, F. M. Ebling, B. Mitchell, R. R. Singh, B. H. Hahn, B. P. Tsao: Comparison of pathogenic and nonpathogenic murine antibodies to DNA: antigen binding and structural characteristics. Int Immunol 6(6), 817-830 (1994) (Pubitemid 24183316)
    • (1994) International Immunology , vol.6 , Issue.6 , pp. 817-830
    • Ohnishi, K.1    Ebling, F.M.2    Mitchell, B.3    Singh, R.R.4    Hahn, B.H.5    Tsao, B.P.6
  • 10
    • 1342300520 scopus 로고    scopus 로고
    • Pathogenic Profiles and Molecular Signatures of Antinuclear Autoantibodies Rescued from NZM2410 Lupus Mice
    • DOI 10.1084/jem.20030132
    • Z. Liang, C. Xie, C. Chen, D. Kreska, K. Hsu, L. Li, X.J. Zhou, C. Mohan: Pathogenic Profiles and Molecular Signatures of Antinuclear Autoantibodies Rescued from NZM2410 Lupus Mice. J Exp Med 199(3), 381-398 (2004) (Pubitemid 38252050)
    • (2004) Journal of Experimental Medicine , vol.199 , Issue.3 , pp. 381-398
    • Liang, Z.1    Xie, C.2    Chen, C.3    Kreska, D.4    Hsu, K.5    Li, L.6    Zhou, X.J.7    Mohan, C.8
  • 11
    • 23744457014 scopus 로고    scopus 로고
    • Pathogenicity of anti-DNA/glomerular autoantibodies - Weighing the evidence
    • DOI 10.1016/j.ddmod.2004.11.008
    • N. Limaye, and C. Mohan: Pathogenicity of anti-DNA and anti-glomerular antibodies: weighing the evidence. Drug Discovery Today: Disease Models 1(4), 395-403. (2004) (Pubitemid 41123748)
    • (2004) Drug Discovery Today: Disease Models , vol.1 , Issue.4 , pp. 395-403
    • Limaye, N.1    Mohan, C.2
  • 12
    • 31044440224 scopus 로고    scopus 로고
    • Identification of autoantibody clusters that best predict lupus disease activity using glomerular proteome arrays
    • DOI 10.1172/JCI23587
    • Q. Li, C. Xie, T. Wu, M. Mackay, C. Aranow, C. Putterman, C. Mohan: Glomerular proteome arrays - a novel approach to uncover autoantibody clusters that best predict disease activity in lupus. J Clin Inves 115(12), 3428-3439 (2005) (Pubitemid 43121831)
    • (2005) Journal of Clinical Investigation , vol.115 , Issue.12 , pp. 3428-3439
    • Quan, L.Z.1    Xie, C.2    Wu, T.3    Mackay, M.4    Aranow, C.5    Putterman, C.6    Mohan, C.7
  • 13
    • 0023784450 scopus 로고
    • Kinetics of glomerular neutrophil influx after lipopolysaccharide in antibody-mediated injury
    • J. A. Savige, D. J. Evans, and A. J. Rees: Kinetics of glomerular neutrophil influx after lipopolysaccharide in antibody-mediated injury. Clin Exp Immunol 73:134-8. (1988)
    • (1988) Clin Exp Immunol , vol.73 , pp. 134-138
    • Savige, J.A.1    Evans, D.J.2    Rees, A.J.3
  • 14
    • 29644442955 scopus 로고    scopus 로고
    • Innate stimuli accentuate end-organ damage by nephrotoxic antibodies via Fc receptor and TLR stimulation and IL-1/TNF-α production
    • Y. Fu, C. Xie, J. Chen, J. Zhu, H. Zhou, J. Thomas, X. J. Zhou, and C. Mohan: Innate immune stimuli dictate endorgan damage by nephrotoxic antibodies via FcR and Toll receptor stimulation and IL-1/TNF-α production. J Immunol 176, 632-639 (2006) (Pubitemid 43023312)
    • (2006) Journal of Immunology , vol.176 , Issue.1 , pp. 632-639
    • Fu, Y.1    Xie, C.2    Chen, J.3    Zhu, J.4    Zhou, H.5    Thomas, J.6    Zhou, X.J.7    Mohan, C.8
  • 15
    • 0141920664 scopus 로고    scopus 로고
    • Complement and the kidney
    • R. J. Quigg: Complement and the kidney. J Immunol 171, 3319-24 (2003) (Pubitemid 37254529)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3319-3324
    • Quigg, R.J.1
  • 16
    • 0032493059 scopus 로고    scopus 로고
    • Antibodies to DNA
    • B. H. Hahn: Antibodies to DNA. N Engl J Med 338, 1359 (1998)
    • (1998) N Engl J Med , vol.338 , pp. 1359
    • Hahn, B.H.1
  • 17
    • 0029899083 scopus 로고    scopus 로고
    • Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies
    • J. B. Lefkowith, and G. S. Gilkeson: Nephritogenic autoantibodies in lupus. Current concepts and continuing controversies. Arthritis Rheum 39, 894 (1996)
    • (1996) Arthritis Rheum , vol.39 , pp. 894
    • Lefkowith, J.B.1    Gilkeson, G.S.2
  • 18
    • 0032999536 scopus 로고
    • Lupus nephritis: Update on pathogenesis and disease mechanisms
    • M. H. Foster, and V. R. Kelley. Lupus nephritis: update on pathogenesis and disease mechanisms. Seminars in Nephrology 19, 173 (1993)
    • (1993) Seminars in Nephrology , vol.19 , pp. 173
    • Foster, M.H.1    Kelley, V.R.2
  • 19
    • 0032512855 scopus 로고    scopus 로고
    • Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis
    • R. Clynes, C. Dumitru, and J. V. Ravetch: Uncoupling of immune complex formation and kidney damage in autoimmune glomerulonephritis. Science 279, 1052 (1998)
    • (1998) Science , vol.279 , pp. 1052
    • Clynes, R.1    Dumitru, C.2    Ravetch, J.V.3
  • 20
    • 0031725199 scopus 로고    scopus 로고
    • Acute nephrotoxic serum nephritis in complement knockout mice: Relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria
    • M. J. Hebert, T. Takano, A. Papayianni, H. G. Rennke, A. Minto, D. J. Salant, M. C. Carroll, and H. R. Brady. Acute nephrotoxic serum nephritis in complement knockout mice: relative roles of the classical and alternate pathways in neutrophil recruitment and proteinuria. Nephrology, Dialysis, Transplantation 13, 2799 (1998)
    • (1998) Nephrology, Dialysis, Transplantation , vol.13 , pp. 2799
    • Hebert, M.J.1    Takano, T.2    Papayianni, A.3    Rennke, H.G.4    Minto, A.5    Salant, D.J.6    Carroll, M.C.7    Brady, H.R.8
  • 21
    • 0031702690 scopus 로고    scopus 로고
    • Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis
    • Y. Suzuki, I. Shirato, K. Okumura, J. V. Ravetch, T. Takai, Y. Tomino, and C. Ra: Distinct contribution of Fc receptors and angiotensin II-dependent pathways in anti-GBM glomerulonephritis. Kidney Int. 54, 1166 (1998)
    • (1998) Kidney Int. , vol.54 , pp. 1166
    • Suzuki, Y.1    Shirato, I.2    Okumura, K.3    Ravetch, J.V.4    Takai, T.5    Tomino, Y.6    Ra, C.7
  • 22
    • 0032434379 scopus 로고    scopus 로고
    • Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice
    • M. Le Hir, C. Haas, M. Marino, and B. Ryffel: Prevention of crescentic glomerulonephritis induced by anti-glomerular membrane antibody in tumor necrosis factor-deficient mice. Lab Invest 78, 1625 (1998)
    • (1998) Lab Invest , vol.78 , pp. 1625
    • Le Hir, M.1    Haas, C.2    Marino, M.3    Ryffel, B.4
  • 23
    • 0031665608 scopus 로고    scopus 로고
    • Improved survival and amelioration of nephrotoxic nephritis in intercellular adhesion molecule-1 knockout mice
    • U. Janssen, T. Ostendorf, S. Gaertner, F. Eitner, H. J. Hedrich, K. J. Assmann, and J. Floege: Improved survival and amelioration of nephrotoxic nephritis in intercellular adhesion molecule-1 knockout mice. J Am Soc Nephrol 9, 1805 (1998)
    • (1998) J Am Soc Nephrol , vol.9 , pp. 1805
    • Janssen, U.1    Ostendorf, T.2    Gaertner, S.3    Eitner, F.4    Hedrich, H.J.5    Assmann, K.J.6    Floege, J.7
  • 24
    • 0032919614 scopus 로고    scopus 로고
    • Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis
    • G. H. Tesch, A. Schwarting, K. Kinoshita, H. Y. Lan, B. J. Rollins, and V. R. Kelley: Monocyte chemoattractant protein-1 promotes macrophage-mediated tubular injury, but not glomerular injury, in nephrotoxic serum nephritis. J Clin lnvest 103, 73 (1999)
    • (1999) J Clin Lnvest , vol.103 , pp. 73
    • Tesch, G.H.1    Schwarting, A.2    Kinoshita, K.3    Lan, H.Y.4    Rollins, B.J.5    Kelley, V.R.6
  • 25
    • 0014296901 scopus 로고
    • Study of autoimmune disease in New Zealand mice. I. Genetic features and natural history of NZB, NZYand NZW strains and NZB-NZW hybrids
    • I. M. Braverman: Study of autoimmune disease in New Zealand mice. I. Genetic features and natural history of NZB, NZYand NZW strains and NZB-NZW hybrids. J Invest Dermatol 50, 483-499 (1968)
    • (1968) J Invest Dermatol , vol.50 , pp. 483-499
    • Braverman, I.M.1
  • 26
    • 0014555475 scopus 로고
    • Autoantibodies and nephritis in the white strain (NZW) of New Zealand mice
    • B. H. Hahn, and L. E. Shulman: Autoantibodies and nephritis in the white strain (NZW) of New Zealand mice. Arthritis Rheum 12, 355-364. (1969)
    • (1969) Arthritis Rheum , vol.12 , pp. 355-364
    • Hahn, B.H.1    Shulman, L.E.2
  • 27
    • 0018863557 scopus 로고
    • Age- and sex-related glomerulonephritis in New Zealand white mice
    • V. E. Kelley, and A. Winkelstein: Age- and sex-related glomerulonephritis in New Zealand white mice. Clin Immunol lmmunopathol 16, 142-150 (1980) (Pubitemid 10106147)
    • (1980) Clinical Immunology and Immunopathology , vol.16 , Issue.2 , pp. 142-150
    • Kelley, V.E.1    Winkelstein, A.2
  • 28
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • O. T. Chan, L. G. Hannum, A. M. Haberman, M. P. Madaio, and M. J. Shlomchik: A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189, 1639 (1999)
    • (1999) J Exp Med , vol.189 , pp. 1639
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 29
    • 0033214474 scopus 로고    scopus 로고
    • B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity
    • O. T. Chan, M. P. Madaio, and M. J. Shlomchik: B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity. J lmmunol 163, 3592-3596 (1999) (Pubitemid 29450878)
    • (1999) Journal of Immunology , vol.163 , Issue.7 , pp. 3592-3596
    • Chan, O.T.M.1    Madaio, M.P.2    Shlomchik, M.J.3
  • 31
    • 0033180576 scopus 로고    scopus 로고
    • Epistatic modifiers of autoimmunity in a murine model of lupus nephritis
    • DOI 10.1016/S1074-7613(00)80088-6
    • L. Morel. X. H. Tian, B. P. Croker, E. K. Wakeland. Epistatic modifiers of autoimmunity in a murine model of lupus nephritis. Immunity 11 (2), 131-9 (1999) (Pubitemid 29428806)
    • (1999) Immunity , vol.11 , Issue.2 , pp. 131-139
    • Morel, L.1    Tian, X.-H.2    Croker, B.P.3    Wakeland, E.K.4
  • 32
    • 34547414073 scopus 로고    scopus 로고
    • The genetics of systemic lupus erythematosus stratified by renal disease: Linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3)
    • A. I. Quintero-Del-Rio, J. A. Kelly, J. Kilpatrick, J. A. James, and J. B. Harley: The genetics of systemic lupus erythematosus stratified by renal disease: linkage at 10q22.3 (SLEN1), 2q34-35 (SLEN2), and 11p15.6 (SLEN3). Genes Immunity 3(S1), S57-S62 (2002)
    • (2002) Genes Immunity , vol.3 , Issue.S1
    • Quintero-Del-Rio, A.I.1    Kelly, J.A.2    Kilpatrick, J.3    James, J.A.4    Harley, J.B.5
  • 37
    • 0029053741 scopus 로고
    • Familia/predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus
    • B. I. Freedman, A. B. Tuttle, and B. J. Spray: Familia/predisposition to nephropathy in African-Americans with non-insulin-dependent diabetes mellitus. Am J Kidney Dis 25, 710-713 (1995)
    • (1995) Am J Kidney Dis , vol.25 , pp. 710-713
    • Freedman, B.I.1    Tuttle, A.B.2    Spray, B.J.3
  • 39
    • 0029867191 scopus 로고    scopus 로고
    • Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease
    • S. Bergman, B. O. Key, K. A. Kirk, D. G. Warnock, and S. G. Rostant: Kidney disease in the first-degree relatives of African-Americans with hypertensive end-stage renal disease. Am J Kidney Dis 27, 341-346 (1996) (Pubitemid 26075842)
    • (1996) American Journal of Kidney Diseases , vol.27 , Issue.3 , pp. 341-346
    • Bergman, S.1    Key, B.O.2    Kirk, K.A.3    Warnock, D.G.4    Rostand, S.G.5
  • 40
    • 0037389562 scopus 로고    scopus 로고
    • Enhanced susceptibility to end-organ disease in the lupus-facilitating NZW mouse strain
    • DOI 10.1002/art.10887
    • C. Xie, X. J. Zhou, X. Liu, and C. Mohan: Enhanced intrinsic susceptibility to renal disease in the lupus facilitating NZW strain. Arthritis Rheum 48, 1080-1092 (2003) (Pubitemid 36418251)
    • (2003) Arthritis and Rheumatism , vol.48 , Issue.4 , pp. 1080-1092
    • Xie, C.1    Zhou, X.J.2    Liu, X.3    Mohan, C.4
  • 41
    • 1842423817 scopus 로고    scopus 로고
    • Strain Distribution Pattern of Susceptibility to Immune-Mediated Nephritis
    • C. Xie, R. Sharma, H. Wang, X. J. Zhou, and C. Mohan: Strain distribution pattern of susceptibility to immune-mediated nephritis. J Immunol 172, 5047-5055 (2004) (Pubitemid 38456432)
    • (2004) Journal of Immunology , vol.172 , Issue.8 , pp. 5047-5055
    • Xie, C.1    Sharma, R.2    Wang, H.3    Zhou, X.J.4    Mohan, C.5


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