Disposition kinetics and pharmacokinetics-pharmacodynamic integration of difloxacin against Staphylococcus aureus isolates from rabbits

Research in Veterinary Science

Volumn 84, Issue 1, 2008, Pages 90-94

  Fernandez varon E ^a   Carceles C M ^a   Marin P ^a   Vancraeynest, D ^b   Montes, A ^a   Sotillo, J ^a   Garcia Martinez J D ^a  

^a UNIVERSITY OF MURCIA   (Spain)

^b GHENT UNIVERSITY   (Belgium)

Author keywords

Difloxacin; MIC; Pharmacodynamics; Pharmacokinetics; Rabbits; S. aureus

Indexed keywords

DICURAL; DIFLOXACIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBACTERIAL ACTIVITY; AREA UNDER THE CURVE; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG HALF LIFE; EUROPE; FEMALE; FLUORESCENCE ANALYSIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; MEAN RESIDENCE TIME; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHARMACODYNAMICS; PLASMA CONCENTRATION-TIME CURVE; RABBIT; SINGLE DRUG DOSE; STAPHYLOCOCCUS AUREUS; STEADY STATE; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTI-BACTERIAL AGENTS; CIPROFLOXACIN; CROSS-OVER STUDIES; FLUOROQUINOLONES; INJECTIONS, INTRAVENOUS; INJECTIONS, SUBCUTANEOUS; RABBITS; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCUS AUREUS;

BACTERIA (MICROORGANISMS); ORYCTOLAGUS CUNICULUS; STAPHYLOCOCCUS AUREUS;

EID: 36049013074     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2007.04.002     Document Type: Article

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