Renoprotective and antihypertensive effects of S-allylcysteine in 5/6 nephrectomized rats

American Journal of Physiology - Renal Physiology

Volumn 293, Issue 5, 2007, Pages

  Cruz, Cristino ^a   Correa Rotter, Ricardo ^a   Sánchez González, Dolores Javier ^b   Hernández Pando, Rogelio ^a   Maldonado, Perla D ^c   Martínez Martínez, Claudia María ^b   Medina Campos, Omar Noel ^d   Tapia, Edilia ^e   Aguilar, Diana ^a   Chirino, Yolanda I ^d   Pedraza Chaverri, José ^d,f  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

^b Laboratorio Multidisciplinario de Investigación   (Mexico)

^c NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^d Universidad Nacional Autonoma de Mexico Facultad de Quimica   (Mexico)

^e INSTITUTO NACIONAL DE CARDIOLOGÍA IGNACIO CHÁVEZ   (Mexico)

^f UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

Aged garlic; Hypertension; Renal injury; Superoxide anion

Indexed keywords

3 NITROTYROSINE; CREATININE; GARLIC EXTRACT; GLYCOPROTEIN GP 91; NEURONAL NITRIC OXIDE SYNTHASE; NITROGEN; POLY(ADENOSINE DIPHOSPHATE RIBOSE); PROTEIN P22; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; S ALLYLCYSTEINE; SUPEROXIDE; UREA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIHYPERTENSIVE ACTIVITY; ARTICLE; BLOOD PRESSURE; CREATININE BLOOD LEVEL; DRUG EFFECT; ENZYME ACTIVITY; HYPERTENSION; KIDNEY INJURY; NEPHRECTOMY; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEINURIA; RAT; RENAL PROTECTION; SYSTOLIC BLOOD PRESSURE; UREA NITROGEN BLOOD LEVEL;

EID: 36048992492     PISSN: 1931857X     EISSN: 15221466     Source Type: Journal    
DOI: 10.1152/ajprenal.00235.2007     Document Type: Article

References (53)

1. Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr 131: 955S-962S, 2001.
2. Banerjee SK, Mukherjee PK, Maulik SK. Garlic as an antioxidant: the good, the bad and the ugly. Phytother Res 17: 97-106, 2003.
3. Bautista-Garcia P, Sanchez-Lozada LG, Cristobal-Garcia M, Tapia E, Soto V, Avila-Casado MC, Marquez-Velasco R, Bojalil R, Franco M, Herrera-Acosta J. Chronic inhibition of NOS-2 ameliorates renal injury, as well as COX-2 and TGF-β1 overexpression, in 5/6 nephrectomized rats. Nephrol Dial Transplant 21: 3074-3081, 2006.
4. Bobadilla NA, Tack I, Tapia E, Sanchez-Lozada LG, Santamaria J, Jimenez F, Striker LJ, Striker GE, Herrera-Acosta J. Pentosan polysulfate prevents glomerular hypertension and structural injury despite persisting hypertension in 5/6 nephrectomy rats. J Am Soc Nephrol 12: 2080-2087, 2001.
5. Borek C. Garlic reduces dementia and heart-disease risk. J Nutr 136: 810S-812S, 2006.
6. Chatterjee PK, Zacharowski K, Cuzzocrea S, Otto M, Thiemermann C. Inhibitors of poly(ADP-ribose) synthetase reduce renal ischemia-reperfusion injury in the anesthetized rat in vivo. FASEB J 14: 641-651, 2000.
7. Chirino YI, Orozco-Ibarra M, Pedraza-Chaverri J. Papel del peroxinitrito en diferentes enfermedades. Rev Invest Clin 58: 350-358, 2006.
8. Cuzzocrea S, Mazzon E, Dugo L, Serraino I, Di Paola R, Britti D, De Sarro A, Pierpaoli S, Caputi A, Masini E, Salvemini D. A role for superoxide in gentamicin-mediated nephropathy in rats. Eur J Pharmacol 450: 67-76, 2002.
9. 2α in smoking and nonsmoking men and women. J Nutr 132: 168-171, 2002.
10. Escobales N, Crespo MJ. Oxidative-nitrosative stress in hypertension. Curr Vasc Pharmacol 3: 231-246, 2005.
11. Fujihara CK, Antunes GR, Mattar AL, Malheiros DM, Vieira JM Jr, Zatz R. Chronic inhibition of nuclear factor-κB attenuates renal injury in the 5/6 renal ablation model. Am J Physiol Renal Physiol 292: F92-F99, 2007.
12. Geng Z, Rong Y, Lau BH. S-allyl cysteine inhibits activation of nuclear factor κB in human T cells. Free Radic Biol Med 23: 345-350, 1997.
13. Gill PS, Wilcox CS. NADPH oxidases in the kidney. Antioxid Redox Signal 8: 1597-1607, 2006.
14. Goligorsky MS, Brodsky SV, Noiri E. NO bioavailability, endothelial dysfunction, and acute renal failure: new insights into pathophysiology. Semin Nephrol 24: 316-323, 2004.
15. Harauma A, Moriguchi T. Aged garlic extract improves blood pressure in spontaneously hypertensive rats more safely than raw garlic. J Nutr 136: 769S-773S, 2006.
16. Herrera-Mundo MN, Silva-Adaya D, Maldonado PD, Galvan-Arzate S, Andres-Martinez L, Perez-de la Cruz V, Pedraza-Chaverri J, Santamaria A. S-allylcysteine prevents the rat from 3-nitropropionic acid-induced hyperactivity, early markers of oxidative stress and mitochondrial dysfunction. Neurosci Res 56: 39-44, 2006.
17. Ide N, Lau BH. Aged garlic extract attenuates intracellular oxidative stress. Phytomedicine 6: 125-131, 1999.
18. Ide N, Lau BH. S-allylcysteine attenuates oxidative stress in endothelial cells. Drug Dev Ind Pharm 25: 619-624, 1999.
19. Imai J, Ide N, Nagae S, Moriguchi T, Matsuura H, Itakura Y. Antioxidant and radical scavenging effects of aged garlic extract and its constituents. Planta Med 60: 417-420, 1994.
20. phox, Rac-1) and tacrolimus-induced nephrotoxicity in a rat renal transplant model. Nephrol Dial Transplant 22: 376-385, 2007.
21. Kim JM, Chang N, Kim WK, Chun HS. Dietary S-allyl- L-cysteine reduces mortality with decreased incidence of stroke and behavioral changes in stroke-prone spontaneously hypertensive rats. Biosci Biotechnol Biochem 70: 1969-1971, 2006.
22. Kim JM, Lee JC, Chang N, Chun HS, Kim WK. S-allyl- L-cysteine attenuates cerebral ischemic injury by scavenging peroxynitrite and inhibiting the activity of extracellular signal-regulated kinase. Free Radic Res 40: 827-835, 2006.
23. Kim KM, Chun SB, Koo MS, Choi WJ, Kim TW, Kwon YG, Chung HT, Billiar TR, Kim YM. Differential regulation of NO availability from macrophages and endothelial cells by the garlic component S-allyl cysteine. Free Radic Biol Med 30: 747-756, 2001.
24. Kiss L, Szabo C. The pathogenesis of diabetic complications: the role of DNA injury and poly(ADP-ribose) polymerase activation in peroxynitrite-mediated cytotoxicity. Mem Inst Oswaldo Cruz 1: 29-37, 2005.
25. Krause RJ, Glocke SC, Elfarra AA. Sulfoxides as urinary metabolites of S-allyl-L-cysteine in rats: evidence for the involvement of flavin-containing monooxygenases. Drug Metab Dispos 30: 1137-1142, 2002.
26. Lawson LD. The composition and chemistry of garlic cloves and processed garlic. In: The Science and Therapeutic Application of Allium sativum L. and Related Species, edited by Koch HP, Lawson LD. Baltimore, MD: Williams & Wilkins, 1996.
27. Lawson LD, Wang ZJ, Hughes BG. γ-glutamyl-S- alkylcysteines in garlic and other Allium spp.: precursors of AGE-dependent trans-1-propenyl. J Nat Prod 54: 436-444, 1991.
28. Lim CS, Vaziri ND. Iron and oxidative stress in renal insufficiency. Am J Nephrol 24: 569-575, 2004.
29. Louhelainen M, Merasto S, Finckenberg P, Lapatto R, Cheng ZJ, Mervaala EM. Lipoic acid supplementation prevents cyclosporine-induced hypertension and nephrotoxicity in spontaneously hypertensive rats. J Hypertens 24: 947-956, 2006.
30. Lowry OH, Rosebrough NJ, Farr A, Randall RJ. Protein measurement with the Folin phenol reagent. J Biol Chem 193: 265-275, 1951.
31. Maldonado PD, Barrera D, Medina-Campos ON, Hernandez-Pando R, Ibarra-Rubio ME, Pedraza-Chaverri J. Aged garlic extract attenuates gentamicin induced renal damage and oxidative stress in rats. Life Sci 73: 2543-2556, 2003.
32. Maldonado PD, Barrera D, Rivero I, Mata R, Medina-Campos ON, Hernandez-Pando R, Pedraza-Chaverri J. Antioxidant S-allylcysteine prevents gentamicin-induced oxidative stress and renal damage. Free Radic Biol Med 35: 317-324, 2003.
33. 1 cells of potassium dichromate-induced toxicity. Food Chem Toxicol 45: 2030-2039, 2007.
34. Modlinger PS, Wilcox CS, Aslam S. Nitric oxide, oxidative stress, and progression of chronic renal failure. Semin Nephrol 24: 354-365, 2004.
35. Morihara N, Ide N, Sumioka I, Kyo E. Aged garlic extract inhibits peroxynitrite-induced hemolysis. Redox Rep 10: 159-165, 2005.
36. Morihara N, Sumioka I, Ide N, Moriguchi T, Uda N, Kyo E. Aged garlic extract maintains cardiovascular homeostasis in mice and rats. J Nutr 136: 777S-781S, 2006.
37. Morihara N, Sumioka I, Moriguchi T, Uda N, Kyo E. Aged garlic extract enhances production of nitric oxide. Life Sci 71: 509-517, 2002.
38. Numagami Y, Ohnishi ST. S-allylcysteine inhibits free radical production, lipid peroxidation and neuronal damage in rat brain ischemia. J Nutr 131: 1100S-1105S, 2001.
39. Obrosova IG, Julius UA. Role for poly(ADP-ribose) polymerase activation in diabetic nephropathy, neuropathy and retinopathy. Curr Vasc Pharmacol 3: 267-283, 2005.
40. Orozco-Ibarra M, Medina-Campos ON, Sanchez-Gonzalez DJ, Martinez-Martinez CM, Floriano-Sanchez E, Santamaria A, Ramirez V, Bobadilla NA, Pedraza-Chaverri J. Evaluation of oxidative stress in D-serine induced nephrotoxicity. Toxicology 229: 123-135, 2007.
41. Pedraza-Chaverri J, Granados-Silvestre MD, Medina-Campos ON, Hernandez-Pando R. Effect of the in vivo catalase inhibition on aminonucleoside nephrosis. Free Radic Biol Med 27: 245-253, 1999.
42. Pedraza-Chaverri J, Maldonado PD, Medina-Campos ON, Olivares-Corichi IM, Granados-Silvestre MA, Hernandez-Pando R, Ibarra-Rubio ME. Garlic ameliorates gentamicin nephrotoxicity: relation to antioxidant enzymes. Free Radic Biol Med 29: 602-611, 2000.
43. Perez-Severiano F, Rodriguez-Perez M, Pedraza-Chaverri J, Maldonado PD, Medina-Campos ON, Ortiz-Plata A, Sanchez-Garcia A, Villeda-Hernandez J, Galvan-Arzate S, Aguilera P, Santamaria A. S-allylcysteine, a garlic-derived antioxidant, ameliorates quinolinic acid-induced neurotoxicity and oxidative damage in rats. Neurochem Int 45: 1175-1183, 2004.
44. Perez-Severiano F, Salvatierra-Sanchez R, Rodriguez-Perez M, Cuevas-Martinez EY, Guevara J, Limon D, Maldonado PD, Medina-Campos ON, Pedraza-Chaverri J, Santamaria A. S-allylcysteine prevents amyloid-β peptide-induced oxidative stress in rat hippocampus and ameliorates learning deficits. Eur J Pharmacol 489: 197-202, 2004.
45. Racz I, Tory K, Gallyas F Jr, Berente Z, Osz E, Jaszlits L, Bernath S, Sumegi B, Rabloczky G, Literati-Nagy P. BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. Biochem Pharmacol 63: 1099-1111, 2002.
46. Romero F, Rodriguez-Iturbe B, Parra G, Gonzalez L, Herrera-Acosta J, Tapia E. Mycophenolate mofetil prevents the progressive renal failure induced by 5/6 renal ablation in rats. Kidney Int 55: 945-955, 1999.
47. Sanchez-Gonzalez DJ, Moro MA, Castillo-Henkel C, Herrera-Gonzalez N, Hernandez-Pando R, Larios-Medina FJ, Cobilt R, Blanco JA, Pedraza-Chaverri J, Villanueva C. Ozone exposure induces iNOS expression and tyrosine nitration in rat aorta. Environ Toxicol Pharmacol 17: 1-7, 2004.
48. Shimizu MH, Coimbra TM, de Araujo M, Menezes LF, Seguro AC. N-acetylcysteine attenuates the progression of chronic renal failure. Kidney Int 68: 2208-2217, 2005.
49. Tain YL, Freshour G, Dikalova A, Griendling KK, Baylis C. Vitamin E reduces glomerulosclerosis, restores renal neuronal NOS, and suppresses oxidative stress in the 5/6 nephrectomized rat. Am J Physiol Renal Physiol 292: F1404-F1410, 2007.
50. Tapia E, Franco M, Sanchez-Lozada LG, Soto V, Avila-Casado C, Santamaria J, Quiroz Y, Rodriguez-Iturbe B, Herrera-Acosta J. Mycophenolate mofetil prevents arteriolopathy and renal injury in subtotal ablation despite persistent hypertension. Kidney Int 63: 994-1002, 2003.
51. Vaziri ND, Dicus M, Ho ND, Boroujerdi-Rad L, Sindhu RK. Oxidative stress and dysregulation of superoxide dismutase and NADPH oxidase in renal insufficiency. Kidney Int 63: 179-185, 2003.
52. Vaziri ND, Oveisi F, Ding Y. Role of increased oxygen free radical activity in the pathogenesis of uremic hypertension. Kidney Int 53: 1748-1754, 1998.
53. Vaziri ND, Rodriguez-Iturbe B. Mechanisms of disease: oxidative stress and inflammation in the pathogenesis of hypertension. Nat Clin Pract Nephrol 2: 582-593, 2006.