메뉴 건너뛰기




Volumn 22, Issue 2, 2007, Pages 376-385

NADPH oxidase subunits (NOX-1, p22phox, Rac-1) and tacrolimus-induced nephrotoxicity in a rat renal transplant model

Author keywords

Anti TGF antibody; NADPH oxidase; Nephrotoxicity; Rat renal transplant model; Tacrolimus; TGF

Indexed keywords

CREATININE; IMMUNOGLOBULIN G1 ANTIBODY; MESSENGER RNA; NITROGEN; PROTEIN P22; PROTEIN SUBUNIT; RAC1 PROTEIN; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TACROLIMUS; THIOREDOXIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA ANTIBODY; UREA;

EID: 33846663966     PISSN: 09310509     EISSN: 14602385     Source Type: Journal    
DOI: 10.1093/ndt/gfl608     Document Type: Article
Times cited : (41)

References (39)
  • 1
    • 0037182107 scopus 로고    scopus 로고
    • Analysis of TGF-β and pro-fibrogenic molecules in a rat cardiac allograft model treated with cyclosporine
    • Khanna AK, Hosenpud JS, Plummer MS, Hosenpud JD. Analysis of TGF-β and pro-fibrogenic molecules in a rat cardiac allograft model treated with cyclosporine. Transplantation 2000; 73: 1543-1549
    • (2000) Transplantation , vol.73 , pp. 1543-1549
    • Khanna, A.K.1    Hosenpud, J.S.2    Plummer, M.S.3    Hosenpud, J.D.4
  • 2
    • 0036433447 scopus 로고    scopus 로고
    • Expression of TGF-β and fibrogenic genes in transplant recipients with tacrolimus and cyclosporine nephrotoxicity
    • Khanna AK, Plummer M, Bromberek C et al. Expression of TGF-β and fibrogenic genes in transplant recipients with tacrolimus and cyclosporine nephrotoxicity. Kidney Int 2002; 62: 2257-2263
    • (2002) Kidney Int , vol.62 , pp. 2257-2263
    • Khanna, A.K.1    Plummer, M.2    Bromberek, C.3
  • 3
    • 0034721335 scopus 로고    scopus 로고
    • Mechanism of the combination immunosuppressive effects of rapamycin with either cyclosporine or tacrolimus
    • Khanna AK. Mechanism of the combination immunosuppressive effects of rapamycin with either cyclosporine or tacrolimus. Transplantation 2000; 70: 690-694
    • (2000) Transplantation , vol.70 , pp. 690-694
    • Khanna, A.K.1
  • 4
    • 0033608385 scopus 로고    scopus 로고
    • Tacrolimus induces increased expression of transforming growth factor-beta in lymphoid and non-lymphoid cells
    • Khanna A, Cairns V, Hosenpud JD. Tacrolimus induces increased expression of transforming growth factor-beta in lymphoid and non-lymphoid cells. Transplantation 1999; 67: 614-619
    • (1999) Transplantation , vol.67 , pp. 614-619
    • Khanna, A.1    Cairns, V.2    Hosenpud, J.D.3
  • 5
    • 0033608710 scopus 로고    scopus 로고
    • Transforming growth factor-β (TGF-β) mimics and anti-TGF-β antibody abrogates the in-vivo effects of cyclosporine: Demonstration of a direct role of TGF- in immunosuppression and nephrotoxicity of CsA
    • Khanna A, Cairns V, Becker CG, Hosenpud JD. Transforming growth factor-β (TGF-β) mimics and anti-TGF-β antibody abrogates the in-vivo effects of cyclosporine: Demonstration of a direct role of TGF- in immunosuppression and nephrotoxicity of CsA. Transplantation 1999; 67: 882-889
    • (1999) Transplantation , vol.67 , pp. 882-889
    • Khanna, A.1    Cairns, V.2    Becker, C.G.3    Hosenpud, J.D.4
  • 6
    • 0035009696 scopus 로고    scopus 로고
    • Role of transforming growth factor-beta(1) in the progression of chronic allograft nephropathy
    • Campistol JM, Inigo P, Larios S et al. Role of transforming growth factor-beta(1) in the progression of chronic allograft nephropathy. Nephrol Dial Transplant 2001; 1 [16 Suppl]: 114
    • (2001) Nephrol Dial Transplant , vol.1 , Issue.16 SUPPL. , pp. 114
    • Campistol, J.M.1    Inigo, P.2    Larios, S.3
  • 7
    • 11144256945 scopus 로고    scopus 로고
    • Anti-transforming growth factor-antibody at low, but not high doses, limits CsA-mediated nephrotoxicity without altering rat cardiac allograft survival: Potential of therapeutic applications
    • Khanna AK, Plummer MS, Hilton G et al. Anti-transforming growth factor-antibody at low, but not high doses, limits CsA-mediated nephrotoxicity without altering rat cardiac allograft survival: potential of therapeutic applications. Circulation 2004; 110: 3822-3829
    • (2004) Circulation , vol.110 , pp. 3822-3829
    • Khanna, A.K.1    Plummer, M.S.2    Hilton, G.3
  • 8
    • 23944447618 scopus 로고    scopus 로고
    • Assessment of oxidative stress in the early posttransplant period: Comparison of cyclosporine A and tacrolimus-based regimens
    • Vural A, Yilmaz MI, Çaǧlar K et al. Assessment of oxidative stress in the early posttransplant period: Comparison of cyclosporine A and tacrolimus-based regimens. Am J Nephrol 2005; 25: 250-255
    • (2005) Am J Nephrol , vol.25 , pp. 250-255
    • Vural, A.1    Yilmaz, M.I.2    Çaǧlar, K.3
  • 9
    • 0141618437 scopus 로고    scopus 로고
    • Attenuation of cyclosporine-induced renal dysfunction by catechin: Possible antioxidant mechanism
    • Anjaneyulu M, Tirkey N, Chopra K. Attenuation of cyclosporine-induced renal dysfunction by catechin: Possible antioxidant mechanism. Ren Fail 2003; 25: 691-707
    • (2003) Ren Fail , vol.25 , pp. 691-707
    • Anjaneyulu, M.1    Tirkey, N.2    Chopra, K.3
  • 10
    • 0347318117 scopus 로고    scopus 로고
    • Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes
    • Herrara B, Murillo MM, Álvarez-Barrientos A et al. Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes. Free Radical Biol Med 2004; 36: 16-26
    • (2004) Free Radical Biol Med , vol.36 , pp. 16-26
    • Herrara, B.1    Murillo, M.M.2    Álvarez-Barrientos, A.3
  • 11
    • 19944432737 scopus 로고    scopus 로고
    • C-Src and hydrogen peroxide mediate transforming growth factor-β1-induced smooth muscle cell-gene expression in 10T1/2 cells
    • Sato M, Kawai-Kowase K, Sato H et al. c-Src and hydrogen peroxide mediate transforming growth factor-β1-induced smooth muscle cell-gene expression in 10T1/2 cells. Arterioscler Thromb Vasc Biol 2005; 25: 341-347
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 341-347
    • Sato, M.1    Kawai-Kowase, K.2    Sato, H.3
  • 12
    • 17644408006 scopus 로고    scopus 로고
    • TGF-β1 impairs renal autoregulation via generation of ROS
    • Sharma K, Cook A, Smith M et al. TGF-β1 impairs renal autoregulation via generation of ROS. Am J Physiol Renal Physiol 2005; 288: F1069-F1077
    • (2005) Am J Physiol Renal Physiol , vol.288
    • Sharma, K.1    Cook, A.2    Smith, M.3
  • 13
    • 20544437490 scopus 로고    scopus 로고
    • Role of reactive oxygen species in TGF-1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells
    • Rhyu DY, Yang Y, Ha H et al. Role of reactive oxygen species in TGF-1-induced mitogen-activated protein kinase activation and epithelial-mesenchymal transition in renal tubular epithelial cells. J Am Soc Nephrol 2005; 16: 667-675
    • (2005) J Am Soc Nephrol , vol.16 , pp. 667-675
    • Rhyu, D.Y.1    Yang, Y.2    Ha, H.3
  • 14
    • 0347711117 scopus 로고    scopus 로고
    • NADPH oxidases: Not just for leukocytes anymore!
    • Bokoch GM, Knaus UG. NADPH oxidases: Not just for leukocytes anymore! Trends Biochem Sci 2003; 28: 502-508
    • (2003) Trends Biochem Sci , vol.28 , pp. 502-508
    • Bokoch, G.M.1    Knaus, U.G.2
  • 15
    • 0042379916 scopus 로고    scopus 로고
    • The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases
    • Cai H, Griendling KK, Harrison DG. The vascular NAD(P)H oxidases as therapeutic targets in cardiovascular diseases. Trends Pharmacol Sci 2003; 24: 471-47
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 471-547
    • Cai, H.1    Griendling, K.K.2    Harrison, D.G.3
  • 16
    • 10644262971 scopus 로고    scopus 로고
    • The Nox family of NAD(P)H oxidases: Host defense and beyond
    • Geiszt M, Leto TL. The Nox family of NAD(P)H oxidases: Host defense and beyond. J Biol Chem 2004; 279: 51715-718
    • (2004) J Biol Chem , vol.279 , pp. 51715-51718
    • Geiszt, M.1    Leto, T.L.2
  • 17
    • 9144257277 scopus 로고    scopus 로고
    • Tissue distribution and putative physiological function of NOX family NADPH oxidases
    • Krause KH. Tissue distribution and putative physiological function of NOX family NADPH oxidases. Jpn J Infect Dis 2004; 57: S28-S29
    • (2004) Jpn J Infect Dis , vol.57
    • Krause, K.H.1
  • 18
    • 0037974569 scopus 로고    scopus 로고
    • Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression
    • Chabrashvili T, Kitiyakara C, Blau J et al. Effects of ANG II type 1 and 2 receptors on oxidative stress, renal NADPH oxidase, and SOD expression. Am J Physiol Renal Integr Comp Physiol 2003; 285: R117-R
    • (2003) Am J Physiol Renal Integr Comp Physiol , vol.285
    • Chabrashvili, T.1    Kitiyakara, C.2    Blau, J.3
  • 19
    • 0024976004 scopus 로고
    • Cyclosporine
    • Kahan BD. Cyclosporine. N Engl J Med 1989; 321: 1725-1738
    • (1989) N Engl J Med , vol.321 , pp. 1725-1738
    • Kahan, B.D.1
  • 20
    • 0027439668 scopus 로고
    • The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK-506. Clinical significance and comparison with cyclosporine
    • Randhawa PS, Shapiro R, Jordan ML et al. The histopathological changes associated with allograft rejection and drug toxicity in renal transplant recipients maintained on FK-506. Clinical significance and comparison with cyclosporine. Am J Surg Pathol 1993; 17: 60-68
    • (1993) Am J Surg Pathol , vol.17 , pp. 60-68
    • Randhawa, P.S.1    Shapiro, R.2    Jordan, M.L.3
  • 21
    • 0029591906 scopus 로고
    • FK-506 nephrotoxicity: Morphologic and physiologic characterization of a rat model
    • Stillman IE, Andoh TF, Burdmann EA et al. FK-506 nephrotoxicity: morphologic and physiologic characterization of a rat model. Lab Invest 1995; 73: 794-803
    • (1995) Lab Invest , vol.73 , pp. 794-803
    • Stillman, I.E.1    Andoh, T.F.2    Burdmann, E.A.3
  • 22
    • 0031463832 scopus 로고    scopus 로고
    • Mechanism of fibrosis in experimental tacrolimus nephrotoxicity
    • Shihab FS, Bennett WM, Tanner AM, Andoh TF. Mechanism of fibrosis in experimental tacrolimus nephrotoxicity. Transplantation 1997; 64: 1829-1837
    • (1997) Transplantation , vol.64 , pp. 1829-1837
    • Shihab, F.S.1    Bennett, W.M.2    Tanner, A.M.3    Andoh, T.F.4
  • 23
    • 0034123022 scopus 로고    scopus 로고
    • Tacrolimus: A further update of its pharmacology and therapeutic use in the management of organ transplantation
    • Plosker GL, Foster RH. Tacrolimus: A further update of its pharmacology and therapeutic use in the management of organ transplantation. Drugs 2000; 59: 323-389
    • (2000) Drugs , vol.59 , pp. 323-389
    • Plosker, G.L.1    Foster, R.H.2
  • 24
    • 33645832791 scopus 로고    scopus 로고
    • Tacrolimus and cyclosporine in vitro and in vivo induce osteopontin mRNA expression in renal tissues
    • Khanna AK. Tacrolimus and cyclosporine in vitro and in vivo induce osteopontin mRNA expression in renal tissues. Nephron Exp Nephrol 2005; 101: 119-126
    • (2005) Nephron Exp Nephrol , vol.101 , pp. 119-126
    • Khanna, A.K.1
  • 25
    • 0038672183 scopus 로고    scopus 로고
    • Cyclosporin A disrupts bradykinin signaling through superoxide
    • Vetter M, Chen ZJ, Chang GD et al. Cyclosporin A disrupts bradykinin signaling through superoxide. Hypertension 2003; 41: 1136-1142
    • (2003) Hypertension , vol.41 , pp. 1136-1142
    • Vetter, M.1    Chen, Z.J.2    Chang, G.D.3
  • 26
    • 0347992787 scopus 로고    scopus 로고
    • Hydrogen peroxide mediates FK506-induced cytotoxicity in renal cells
    • Zhou X, Yang G, Davis CA et al. Hydrogen peroxide mediates FK506-induced cytotoxicity in renal cells. Kidney Int 2004; 65: 139-147
    • (2004) Kidney Int , vol.65 , pp. 139-147
    • Zhou, X.1    Yang, G.2    Davis, C.A.3
  • 27
    • 17844369761 scopus 로고    scopus 로고
    • Effect of renal transplantation on biomarkers of inflammation and oxidative stress in end-stage renal disease patients
    • Simmons EM, Langone A, Sezer MT et al. Effect of renal transplantation on biomarkers of inflammation and oxidative stress in end-stage renal disease patients. Transplantation 2005; 79: 914-919
    • (2005) Transplantation , vol.79 , pp. 914-919
    • Simmons, E.M.1    Langone, A.2    Sezer, M.T.3
  • 28
    • 0029736871 scopus 로고    scopus 로고
    • Redox-mediated activation of latent transforming growth factor-beta 1
    • Barcellos-Hoff MH, Dix TA. Redox-mediated activation of latent transforming growth factor-beta 1. Mol Endocrinol 1996; 10: 1077-1083
    • (1996) Mol Endocrinol , vol.10 , pp. 1077-1083
    • Barcellos-Hoff, M.H.1    Dix, T.A.2
  • 29
    • 0028913181 scopus 로고
    • Lipid peroxidation accompanies cyclosporine nephrotoxicity: Effects of vitamin E
    • Wang C, Salahudeen AK. Lipid peroxidation accompanies cyclosporine nephrotoxicity: Effects of vitamin E. Kidney Int 1995; 47: 927-934
    • (1995) Kidney Int , vol.47 , pp. 927-934
    • Wang, C.1    Salahudeen, A.K.2
  • 30
    • 0027454175 scopus 로고
    • Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes
    • Ahmed SS, Strobel HW, Napoli KL, Grevel J. Adrenochrome reaction implicates oxygen radicals in metabolism of cyclosporine A and FK-506 in rat and human liver microsomes. J Pharmacol Exp Ther 1993; 265: 1047-1054
    • (1993) J Pharmacol Exp Ther , vol.265 , pp. 1047-1054
    • Ahmed, S.S.1    Strobel, H.W.2    Napoli, K.L.3    Grevel, J.4
  • 31
    • 0028863110 scopus 로고
    • Oxygen radical formation during cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes at varying hydrogen ion concentrations
    • Ahmed SS, Napoli KL, Strobel HW. Oxygen radical formation during cytochrome P450-catalyzed cyclosporine metabolism in rat and human liver microsomes at varying hydrogen ion concentrations. Mol Cell Biochem 1995; 151: 131-140
    • (1995) Mol Cell Biochem , vol.151 , pp. 131-140
    • Ahmed, S.S.1    Napoli, K.L.2    Strobel, H.W.3
  • 32
    • 0028135549 scopus 로고
    • Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity
    • Serino F, Grevel J, Napoli KL et al. Oxygen radical formation by the cytochrome P450 system as a cellular mechanism for cyclosporine toxicity. Transplant Proc 1994; 26: 2916-2917
    • (1994) Transplant Proc , vol.26 , pp. 2916-2917
    • Serino, F.1    Grevel, J.2    Napoli, K.L.3
  • 33
    • 0006952397 scopus 로고
    • New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: The relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney
    • Yamada K, Sugisaki Y, Suzuki S et al. New morphological changes induced by FK506 in a short period in the rat kidney and the effect of superoxide dismutase and OKY-046 on THEM: The relationship of FK506 nephrotoxicity to lipid peroxidation and change in production of thromboxane A2 in the kidney. Transplant Int 1992; 5: S564-S567
    • (1992) Transplant Int , vol.5
    • Yamada, K.1    Sugisaki, Y.2    Suzuki, S.3
  • 34
    • 0033163392 scopus 로고    scopus 로고
    • Reactive oxygen and nitrogen intermediates increase transforming growth factor-betal release from human epithelial alveolar cells through two different mechanisms
    • Bellocq A, Azoulay E, Marullo S et al. Reactive oxygen and nitrogen intermediates increase transforming growth factor-betal release from human epithelial alveolar cells through two different mechanisms. Am J Respir Cell Mol Biol 1999; 21: 128-136
    • (1999) Am J Respir Cell Mol Biol , vol.21 , pp. 128-136
    • Bellocq, A.1    Azoulay, E.2    Marullo, S.3
  • 35
    • 0033947293 scopus 로고    scopus 로고
    • TGF- Increases albumin permeability of isolated rat glomeruli via hydroxyl radical
    • Sharma R, Khanna AK, Sharma M, Savin V. TGF- increases albumin permeability of isolated rat glomeruli via hydroxyl radical. Kidney Int 2000; 58: 131-136
    • (2000) Kidney Int , vol.58 , pp. 131-136
    • Sharma, R.1    Khanna, A.K.2    Sharma, M.3    Savin, V.4
  • 36
    • 18844417923 scopus 로고    scopus 로고
    • Tempol attenuates the development of hypertensive renal injury in Dahl salt-sensitive rats
    • Hisaki R, Fujita H, Saito F, Kushiro T. Tempol attenuates the development of hypertensive renal injury in Dahl salt-sensitive rats. Am J Hypertens 2005; 18: 707-713
    • (2005) Am J Hypertens , vol.18 , pp. 707-713
    • Hisaki, R.1    Fujita, H.2    Saito, F.3    Kushiro, T.4
  • 37
    • 3242749828 scopus 로고    scopus 로고
    • Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress
    • Zhang JJ, Bledsoe G, Kato K et al. Tissue kallikrein attenuates salt-induced renal fibrosis by inhibition of oxidative stress. Kidney Int 2004; 66: 722-732
    • (2004) Kidney Int , vol.66 , pp. 722-732
    • Zhang, J.J.1    Bledsoe, G.2    Kato, K.3
  • 38
    • 5044230814 scopus 로고    scopus 로고
    • Role of aberrant iron homeostasis in the upregulation of transforming growth factor-betal in the kidney of angiotensin II-induced hypertensive rats
    • Saito K, Ishizaka N, Aizawa T et al. Role of aberrant iron homeostasis in the upregulation of transforming growth factor-betal in the kidney of angiotensin II-induced hypertensive rats. Hypertens Res 2004; 27: 599-607
    • (2004) Hypertens Res , vol.27 , pp. 599-607
    • Saito, K.1    Ishizaka, N.2    Aizawa, T.3
  • 39
    • 0242609831 scopus 로고    scopus 로고
    • L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats
    • Fujii S, Zhang L, Igarashi J, Kosaka H. L-arginine reverses p47phox and gp91phox expression induced by high salt in Dahl rats. Hypertension. 2003; 42: 1014-1020
    • (2003) Hypertension , vol.42 , pp. 1014-1020
    • Fujii, S.1    Zhang, L.2    Igarashi, J.3    Kosaka, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.