Gap junction-mediated antigen transport in immune responses

Trends in Immunology

Volumn 28, Issue 11, 2007, Pages 463-466

  Handel, Andreas ^a   Yates, Andrew ^a   Pilyugin, Sergei S ^b   Antia, Rustom ^a  

^a EMORY UNIVERSITY   (United States)

^b UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; GAP JUNCTION MEDIATED ANTIGEN; GAP JUNCTION PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; CELL COMMUNICATION; CELL DEATH; GAP JUNCTION; IMMUNE RESPONSE; IN VITRO SELECTION;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, VIRAL; BIOLOGICAL TRANSPORT; CELL COMMUNICATION; CONNEXINS; DENDRITIC CELLS; EPITOPES; GAP JUNCTIONS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS;

EID: 36048984176     PISSN: 14714906     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.it.2007.08.006     Document Type: Article

References (48)

1. Balkwill F.R., and Burke F. The cytokine network. Immunol. Today 10 (1989) 299-304
2. Friedl P., et al. Tuning immune responses: diversity and adaptation of the immunological synapse. Nat. Rev. Immunol. 5 (2005) 532-545
3. Davis D.M. Intercellular transfer of cell-surface proteins is common and can affect many stages of an immune response. Nat. Rev. Immunol. 7 (2007) 238-243
4. Bennet M.V.L., et al. New roles for astrocytes: gap junction hemichannels have something to communicate. Trends Neurosci. 26 (2003) 610-617
5. Saez J.C., et al. Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev. 83 (2003) 1359-1400
6. Harris A.L. Emerging issues of connexin channels: biophysics fills the gap. Q. Rev. Biophys. 34 (2001) 325-472
7. Evans W.H., et al. The gap junction cellular internet: connexin hemichannels enter the signalling limelight. Biochem. J. 397 (2006) 1-14
8. De Maio A., et al. Gap junctions, homeostasis, and injury. J. Cell. Physiol. 191 (2002) 269-282
9. Chanson M. Gap junctional communication in tissue inflammation and repair. Biochim. Biophys. Acta 1711 (2005) 197-207
10. Montecino-Rodriguez E., et al. Expression of connexin 43 (cx43) is critical for normal hematopoiesis. Blood 96 (2000) 917-924
11. Rozental R., et al. Gap junctions in the cardiovascular and immune systems. Braz. J. Med. Biol. Res. 33 (2000) 365-368
12. Bruzzone R., and Dermietzel R. Structure and function of gap junctions in the developing brain. Cell Tissue Res. 326 (2006) 239-248
13. Aasen T., et al. Reduced expression of multiple gap junction proteins is a feature of cervical dysplasia. Mol. Cancer 4 (2005) 31
14. El-Sabban M.E., et al. Human T-cell lymphotropic virus type 1-transformed cells induce angiogenesis and establish functional gap junctions with endothelial cells. Blood 99 (2002) 3383-3389
15. Contreras J.E., et al. Role of connexin-based gap junction channels and hemichannels in ischemia-induced cell death in nervous tissue. Brain Res. Brain Res. Rev. 47 (2004) 290-303
16. Wei C.-J., et al. Connexins and cell signaling in development and disease. Annu. Rev. Cell Dev. Biol. 20 (2004) 811-838
17. Krenacs T., and Rosendaal M. Immunohistological detection of gap junctions in human lymphoid tissue: connexin43 in follicular dendritic and lymphoendothelial cells. J. Histochem. Cytochem. 43 (1995) 1125-1137
18. Krenacs T., and Rosendaal M. Gap-junction communication pathways in germinal center reactions. Dev. Immunol. 6 (1998) 111-118
19. Nihei O.K., et al. A novel form of cellular communication among thymic epithelial cells: intercellular calcium wave propagation. Am. J. Physiol. Cell Physiol. 285 (2003) C1304-C1313
20. Alves L.A., et al. Gap junction modulation by extracellular signaling molecules: the thymus model. Braz. J. Med. Biol. Res. 33 (2000) 457-465
21. Wong C.W., et al. Connexins in leukocytes: shuttling messages?. Cardiovasc. Res. 62 (2004) 357-367
22. Oviedo-Orta E. Gap junction intercellular communication during lymphocyte transendothelial migration. Cell Biol. Int. 26 (2002) 253-263
23. Saez J.C., et al. Gap junctions in cells of the immune system: structure, regulation and possible functional roles. Braz. J. Med. Biol. Res. 33 (2000) 447-455
24. Oviedo-Orta E., and Evans W.H. Gap junctions and connexin-mediated communication in the immune system. Biochim. Biophys. Acta 1662 (2004) 102-112
25. Fischer N.O., et al. Hsv-2 disrupts gap junctional intercellular communication between mammalian cells in vitro. J. Virol. Methods 91 (2001) 157-166
26. Oelze I., et al. Human papillomavirus type 16 e5 protein affects cell-cell communication in an epithelial cell line. J. Virol. 69 (1995) 4489-4494
27. Tomakidi P., et al. Connexin 43 expression is downregulated in raft cultures of human keratinocytes expressing the human papillomavirus type 16 e5 protein. Cell Tissue Res. 301 (2000) 323-327
28. Ennaji M.M., et al. Alterations in cell-cell communication in human papillomavirus type 16 (hpv16) transformed rat myoblasts. Cell. Mol. Biol. 41 (1995) 481-498
29. Jara P.I., et al. Leukocytes express connexin 43 after activation with lipopolysaccharide and appear to form gap junctions with endothelial cells after ischemia-reperfusion. Proc. Natl. Acad. Sci. U. S. A. 92 (1995) 7011-7015
30. Hu J., and Cotgreave I.A. Differential regulation of gap junctions by proinflammatory mediators in vitro. J. Clin. Invest. 99 (1997) 2312-2316
31. Eugenin E.A., et al. Tnf-alpha plus ifn-gamma induce connexin43 expression and formation of gap junctions between human monocytes/macrophages that enhance physiological responses. J. Immunol. 170 (2003) 1320-1328
32. Garg S., et al. Staphylococcus aureus-derived peptidoglycan induces cx43 expression and functional gap junction intercellular communication in microglia. J. Neurochem 95 (2005) 475-483
33. Zhao Y., et al. The tlr3 ligand polyi: C downregulates connexin 43 expression and function in astrocytes by a mechanism involving the nf-kappab and pi3 kinase pathways. Glia 54 (2006) 775-785
34. Matsue H., et al. Gap junction-mediated intercellular communication between dendritic cells (DCs) is required for effective activation of DCs. J. Immunol. 176 (2006) 181-190
35. Oviedo-Orta E., et al. Immunoglobulin and cytokine expression in mixed lymphocyte cultures is reduced by disruption of gap junction intercellular communication. FASEB J. 15 (2001) 768-774
36. Neijssen J., et al. Cross-presentation by intercellular peptide transfer through gap junctions. Nature 434 (2005) 83-88
37. Heath W.R., and Carbone F.R. Coupling and cross-presentation. Nature 434 (2005) 27-28
38. Griffiths P.D. Mind the gap. Rev. Med. Virol. 15 (2005) 285-286
39. Li G., and Herlyn M. Information sharing and collateral damage. Trends Mol. Med. 11 (2005) 350-352
40. Sille F.C.M., et al. T cell priming by tissue-derived dendritic cells: new insights from recent murine studies. Cell. Immunol. 237 (2005) 77-85
41. Yewdell J.W., and Haeryfar S.M.M. Understanding presentation of viral antigens to cd8+ t cells in vivo: the key to rational vaccine design. Annu. Rev. Immunol. 23 (2005) 651-682
42. Cresswell P. Mechanisms of mhc class i-restricted antigen processing and cross-presentation. Immunol. Rev. 207 (2005) 145-157
43. Trombetta E.S., and Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu. Rev. Immunol. 23 (2005) 975-1028
44. Heath W.R., et al. Cross-presentation, dendritic cell subsets, and the generation of immunity to cellular antigens. Immunol. Rev. 199 (2004) 9-26
45. Efstathiou S., and Preston C.M. Towards an understanding of the molecular basis of herpes simplex virus latency. Virus Res. 111 (2005) 108-119
46. Kent J.R., et al. Herpes simplex virus latency-associated transcript gene function. J. Neurovirol. 9 (2003) 285-290
47. Guermonprez P., et al. Antigen presentation and t cell stimulation by dendritic cells. Annu. Rev. Immunol. 20 (2002) 621-667
48. Alves L.A., et al. Gap junctions: a novel route for direct cell-cell communication in the immune system?. Immunol. Today 19 (1998) 269-275