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Volumn 98, Issue 5, 2007, Pages 1088-1095

Common haplotypes of the C-reactive protein gene and circulating leptin levels influence the interindividual variability in serum C-reactive protein levels - The Segovia study

Author keywords

C reactive protein; Genetic; Inflammation; Leptin; Population

Indexed keywords

C REACTIVE PROTEIN; LEPTIN;

EID: 36048969861     PISSN: 03406245     EISSN: None     Source Type: Journal    
DOI: 10.1160/TH07-03-0231     Document Type: Article
Times cited : (17)

References (42)
  • 1
    • 0034702485 scopus 로고    scopus 로고
    • Low grade inflammation and coronary heart disease: Prospective study and updated meta-analyses
    • Danesh J, Whincup P, Walker M, et al. Low grade inflammation and coronary heart disease: prospective study and updated meta-analyses. Br Med J 2000; 321: 199-204.
    • (2000) Br Med J , vol.321 , pp. 199-204
    • Danesh, J.1    Whincup, P.2    Walker, M.3
  • 2
    • 16644382305 scopus 로고    scopus 로고
    • C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men
    • Laaksonen DE, Niskanen L, Nyyssonen K, et al. C-reactive protein and the development of the metabolic syndrome and diabetes in middle-aged men. Diabetologia 2004; 47: 1403-1410.
    • (2004) Diabetologia , vol.47 , pp. 1403-1410
    • Laaksonen, D.E.1    Niskanen, L.2    Nyyssonen, K.3
  • 3
    • 3242662149 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and the prediction of cardiovascular events in the Framingham Off-spring Study
    • Rutter MK, Meigs JB, Sullivan LM, et al. C-reactive protein, the metabolic syndrome, and the prediction of cardiovascular events in the Framingham Off-spring Study. Circulation 2004; 110: 380-385.
    • (2004) Circulation , vol.110 , pp. 380-385
    • Rutter, M.K.1    Meigs, J.B.2    Sullivan, L.M.3
  • 4
    • 0037469255 scopus 로고    scopus 로고
    • C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: An 8-year follow-up of 14,719 initially healthy American women
    • Ridker PM, Buring JE, Cook NR, et al. C-reactive protein, the metabolic syndrome, and risk of incident cardiovascular events: an 8-year follow-up of 14,719 initially healthy American women. Circulation 2003; 107: 391-397.
    • (2003) Circulation , vol.107 , pp. 391-397
    • Ridker, P.M.1    Buring, J.E.2    Cook, N.R.3
  • 5
    • 33845997475 scopus 로고    scopus 로고
    • Metabolic syndrome and C-reactive protein in the general population: JMS Cohort Study
    • Ishikawa S, Kayaba K, Gotoh T, et al. Metabolic syndrome and C-reactive protein in the general population: JMS Cohort Study. Circ J 2007; 71: 26-31.
    • (2007) Circ J , vol.71 , pp. 26-31
    • Ishikawa, S.1    Kayaba, K.2    Gotoh, T.3
  • 6
    • 0034604248 scopus 로고    scopus 로고
    • Chronic subclinical inflammation as part of the insulin resistance syndrome: The Insulin Resistance Atherosclerosis Study (IRAS)
    • Festa A, D'Agostino R Jr, Howard G, et al. Chronic subclinical inflammation as part of the insulin resistance syndrome: the Insulin Resistance Atherosclerosis Study (IRAS). Circulation 2000; 102: 42-47.
    • (2000) Circulation , vol.102 , pp. 42-47
    • Festa, A.1    D'Agostino Jr, R.2    Howard, G.3
  • 7
    • 28244481060 scopus 로고    scopus 로고
    • C-reactive protein and its role in metabolic syndrome: Mendelian randomisation study
    • Timpson NJ, Lawlor DA, Harbord RM, et al. C-reactive protein and its role in metabolic syndrome: mendelian randomisation study. Lancet 2005; 366: 1954-1959.
    • (2005) Lancet , vol.366 , pp. 1954-1959
    • Timpson, N.J.1    Lawlor, D.A.2    Harbord, R.M.3
  • 8
    • 0032943709 scopus 로고    scopus 로고
    • C-reactive protein in healthy subjects: Associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue?
    • Yudkin JS, Stehouwer CD, Emeis JJ, et al. C-reactive protein in healthy subjects: associations with obesity, insulin resistance, and endothelial dysfunction: a potential role for cytokines originating from adipose tissue? Arterioscler Thromb Vasc Biol 1999; 19: 972-978.
    • (1999) Arterioscler Thromb Vasc Biol , vol.19 , pp. 972-978
    • Yudkin, J.S.1    Stehouwer, C.D.2    Emeis, J.J.3
  • 9
    • 0038542899 scopus 로고    scopus 로고
    • High sensitivity C-reactive protein as an independent risk factor for essential hypertension
    • Sung KC, Suh JY, Kim BS, et al. High sensitivity C-reactive protein as an independent risk factor for essential hypertension. Am J Hypertens 2003; 16: 429-433.
    • (2003) Am J Hypertens , vol.16 , pp. 429-433
    • Sung, K.C.1    Suh, J.Y.2    Kim, B.S.3
  • 10
    • 0042868820 scopus 로고    scopus 로고
    • C-reactive protein concentration distribution among US children and young adults: Findings from the National Health and Nutrition Examination Survey, 1999-2000
    • Ford ES, Giles WH, Myers GL, et al. C-reactive protein concentration distribution among US children and young adults: findings from the National Health and Nutrition Examination Survey, 1999-2000. Clin Chem 2003; 49: 1353-1357.
    • (2003) Clin Chem , vol.49 , pp. 1353-1357
    • Ford, E.S.1    Giles, W.H.2    Myers, G.L.3
  • 11
    • 1542299014 scopus 로고    scopus 로고
    • Distribution and correlates of C-reactive protein concentrations among adult US women
    • Ford ES, Giles WH, Mokdad AH et al. Distribution and correlates of C-reactive protein concentrations among adult US women. Clin Chem 2004; 50: 574-581.
    • (2004) Clin Chem , vol.50 , pp. 574-581
    • Ford, E.S.1    Giles, W.H.2    Mokdad, A.H.3
  • 12
    • 20544459972 scopus 로고    scopus 로고
    • Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels
    • Carlson CS, Aldred SF, Lee PK, et al. Polymorphisms within the C-reactive protein (CRP) promoter region are associated with plasma CRP levels. Am J Hum Genet 2005; 77: 64-77.
    • (2005) Am J Hum Genet , vol.77 , pp. 64-77
    • Carlson, C.S.1    Aldred, S.F.2    Lee, P.K.3
  • 13
    • 0035864605 scopus 로고    scopus 로고
    • Familial and genetic determinants of systemic markers of inflammation: The NHLBI family heart study
    • Pankow JS, Folsom AR, Cushman M, et al. Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. Atherosclerosis 2001; 154: 681-689.
    • (2001) Atherosclerosis , vol.154 , pp. 681-689
    • Pankow, J.S.1    Folsom, A.R.2    Cushman, M.3
  • 14
    • 33846100236 scopus 로고    scopus 로고
    • C-reactive protein, an "intermediate" phenotype, for inflammation: Human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/ beta-adrenergic pathway loci
    • Wessel J, Moratorio G, Rao F et al. C-reactive protein, an "intermediate" phenotype, for inflammation: human twin studies reveal heritability, association with blood pressure and the metabolic syndrome, and the influence of common polymorphism at catecholaminergic/ beta-adrenergic pathway loci. J Hypertension 2007; 25: 329-343.
    • (2007) J Hypertension , vol.25 , pp. 329-343
    • Wessel, J.1    Moratorio, G.2    Rao, F.3
  • 15
    • 10044287426 scopus 로고    scopus 로고
    • Relation of polymorphism within the C-reactive protein gene and plasma CRP levels
    • Suk HJ, Ridker PM, Cook NR, et al. Relation of polymorphism within the C-reactive protein gene and plasma CRP levels. Atherosclerosis 2005; 178: 139-145.
    • (2005) Atherosclerosis , vol.178 , pp. 139-145
    • Suk, H.J.1    Ridker, P.M.2    Cook, N.R.3
  • 16
    • 10044264650 scopus 로고    scopus 로고
    • A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein
    • Kovacs A, Green F, Hansson LO, et al. A novel common single nucleotide polymorphism in the promoter region of the C-reactive protein gene associated with the plasma concentration of C-reactive protein. Atherosclerosis 2005; 178: 193-198.
    • (2005) Atherosclerosis , vol.178 , pp. 193-198
    • Kovacs, A.1    Green, F.2    Hansson, L.O.3
  • 17
    • 10744231062 scopus 로고    scopus 로고
    • Human CRP gene polymorphism influences CRP levels: Implications for the prediction and pathogenesis of coronary heart disease
    • Brull DJ, Serrano N, Zito F, et al. Human CRP gene polymorphism influences CRP levels: implications for the prediction and pathogenesis of coronary heart disease. Arterioscler Thromb Vasc Biol 2003; 23: 2063-2069.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2063-2069
    • Brull, D.J.1    Serrano, N.2    Zito, F.3
  • 18
    • 14544271524 scopus 로고    scopus 로고
    • Definition and clinical importance of haplotypes
    • Crawford DC, Nickerson DA. Definition and clinical importance of haplotypes. Annu Rev Med 2005; 56: 303-320.
    • (2005) Annu Rev Med , vol.56 , pp. 303-320
    • Crawford, D.C.1    Nickerson, D.A.2
  • 19
    • 21544446404 scopus 로고    scopus 로고
    • Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level
    • Szalai AJ, Wu J, Lange EM, et al. Single-nucleotide polymorphisms in the C-reactive protein (CRP) gene promoter that affect transcription factor binding, alter transcriptional activity, and associate with differences in baseline serum CRP level. J Mol Med 2005; 83: 440-447.
    • (2005) J Mol Med , vol.83 , pp. 440-447
    • Szalai, A.J.1    Wu, J.2    Lange, E.M.3
  • 20
    • 28144450650 scopus 로고    scopus 로고
    • Prevalence of the metabolic syndrome (ATP-III criteria). Population-based study of rural and urban areas in the Spanish province of Segovia
    • Martínez-Larrad MT, Fernández-Pérez C, González-Sánchez JL, et al. Prevalence of the metabolic syndrome (ATP-III criteria). Population-based study of rural and urban areas in the Spanish province of Segovia. Med Clin (Barc) 2005; 125: 481-486.
    • (2005) Med Clin (Barc) , vol.125 , pp. 481-486
    • Martínez-Larrad, M.T.1    Fernández-Pérez, C.2    González-Sánchez, J.L.3
  • 21
    • 33846007241 scopus 로고    scopus 로고
    • Diagnosis and Classification of Diabetes Mellitus
    • American Diabetes Association
    • American Diabetes Association. Diagnosis and Classification of Diabetes Mellitus. Diabetes Care 2007; 30: S42-47.
    • (2007) Diabetes Care , vol.30
  • 22
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta cell function from fasting plasma glucose and insulin concentration in man
    • Matthews DR, Hosker JP, Rudenski AS, et al. Homeostasis model assessment: insulin resistance and beta cell function from fasting plasma glucose and insulin concentration in man. Diabetologia 1985, 28: 412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3
  • 23
    • 18444369013 scopus 로고    scopus 로고
    • The estructure of haplotype blocks in the human genome
    • Gabriel SB, Schaffner SF, Nguyen H, et al. (2002). The estructure of haplotype blocks in the human genome. Science 2002; 296: 2225-2229.
    • (2002) Science 2002 , vol.296 , pp. 2225-2229
    • Gabriel, S.B.1    Schaffner, S.F.2    Nguyen, H.3
  • 24
    • 1642313766 scopus 로고    scopus 로고
    • A new algorith for haplotype-based association analysis: The Stochastic-EM algorithm
    • Treoguet DA, Escolano S, Tiret L. A new algorith for haplotype-based association analysis: the Stochastic-EM algorithm. Ann Human Gen 2004; 68: 165-177.
    • (2004) Ann Human Gen , vol.68 , pp. 165-177
    • Treoguet, D.A.1    Escolano, S.2    Tiret, L.3
  • 25
    • 33645800174 scopus 로고    scopus 로고
    • Contribution of clinical correlates and 13 C-Reactive Protein gene polymorphisms to the interindividual variability in serum C-reactive protein levels
    • Kathiresan S, Larson MG, Vasan RS, et al. Contribution of clinical correlates and 13 C-Reactive Protein gene polymorphisms to the interindividual variability in serum C-reactive protein levels. Circulation 2006; 113: 1415-1423.
    • (2006) Circulation , vol.113 , pp. 1415-1423
    • Kathiresan, S.1    Larson, M.G.2    Vasan, R.S.3
  • 26
    • 33845441144 scopus 로고    scopus 로고
    • Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey
    • Crawford DC, Sanders CL, Qin X,et al. Genetic variation is associated with C-reactive protein levels in the Third National Health and Nutrition Examination Survey. Circulation 2006; 114: 2458-2465.
    • (2006) Circulation , vol.114 , pp. 2458-2465
    • Crawford, D.C.1    Sanders, C.L.2    Qin, X.3
  • 27
    • 33846087071 scopus 로고    scopus 로고
    • Is leptin an important physiological regulator of CRP?
    • Hutchinson WL, Coll AP, Gallimore JR, et al. Is leptin an important physiological regulator of CRP? Nat Med 2007; 13: 17-18.
    • (2007) Nat Med , vol.13 , pp. 17-18
    • Hutchinson, W.L.1    Coll, A.P.2    Gallimore, J.R.3
  • 28
    • 33846083468 scopus 로고    scopus 로고
    • Is leptin an important physiological regulator of CRP?
    • Farooqui IS, O'Rahilly S. Is leptin an important physiological regulator of CRP? Nat Med 2007; 13: 16-17.
    • (2007) Nat Med , vol.13 , pp. 16-17
    • Farooqui, I.S.1    O'Rahilly, S.2
  • 29
    • 33846107585 scopus 로고    scopus 로고
    • Is leptin an important physiological regulator of CRP?
    • Gertler A, Niv-Spector L, Reicher S. Is leptin an important physiological regulator of CRP? Nat Med 2007; 13: 18-19.
    • (2007) Nat Med , vol.13 , pp. 18-19
    • Gertler, A.1    Niv-Spector, L.2    Reicher, S.3
  • 30
    • 33846083468 scopus 로고    scopus 로고
    • Is leptin an important physiological regulator of CRP?
    • Zhao A. Is leptin an important physiological regulator of CRP? Nat Med 2007; 13: 20-21.
    • (2007) Nat Med , vol.13 , pp. 20-21
    • Zhao, A.1
  • 31
    • 2442581240 scopus 로고    scopus 로고
    • Independent association between plasma leptin and C-reactive protein in healthy humans
    • Shamsuzzaman AS, Winnicki M, Wolk R, et al. Independent association between plasma leptin and C-reactive protein in healthy humans. Circulation 2004, 109: 2181-2185.
    • (2004) Circulation , vol.109 , pp. 2181-2185
    • Shamsuzzaman, A.S.1    Winnicki, M.2    Wolk, R.3
  • 32
    • 25444530651 scopus 로고    scopus 로고
    • Relation of plasma leptin to C-reactive protein in older adults (from the Invecchiare nel Chianti Study)
    • Ble A, Windham G, Bandinelli S, et al. Relation of plasma leptin to C-reactive protein in older adults (from the Invecchiare nel Chianti Study). Am J Cardiol 2005; 96: 991-995.
    • (2005) Am J Cardiol , vol.96 , pp. 991-995
    • Ble, A.1    Windham, G.2    Bandinelli, S.3
  • 33
    • 33645746168 scopus 로고    scopus 로고
    • Induction of leptin resistance through direct interaction of C-reactive protein with leptin
    • Chen K, Li F, Li J, et al. Induction of leptin resistance through direct interaction of C-reactive protein with leptin. Nat Med 2006; 12: 425-432.
    • (2006) Nat Med , vol.12 , pp. 425-432
    • Chen, K.1    Li, F.2    Li, J.3
  • 34
    • 0035209720 scopus 로고    scopus 로고
    • Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals
    • Van Dielen FMH, van't Veer C, Schols AM et al. Increased leptin concentrations correlate with increased concentrations of inflammatory markers in morbidly obese individuals. Int J Obesity 2001; 25: 1759-1766.
    • (2001) Int J Obesity , vol.25 , pp. 1759-1766
    • Van Dielen, F.M.H.1    van't Veer, C.2    Schols, A.M.3
  • 35
    • 33745302431 scopus 로고    scopus 로고
    • Increased cardiovascular risk markers in obesity are associated with body adiposity: Role of leptin
    • Gómez-Ambrosi J, salvador J, Silva C, et al. Increased cardiovascular risk markers in obesity are associated with body adiposity: role of leptin. Thromb Haemost 2006; 95: 991-996.
    • (2006) Thromb Haemost , vol.95 , pp. 991-996
    • Gómez-Ambrosi, J.1    salvador, J.2    Silva, C.3
  • 36
    • 15944416743 scopus 로고    scopus 로고
    • Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess
    • Chan JL, Bullen J, Stoyneva V, et al. Recombinant methionyl human leptin administration to achieve high physiologic or pharmacologic leptin levels does not alter circulating inflammatory marker levels in humans with leptin sufficiency or excess. J Clin Endocrinol Metab 2005; 90: 1618-1624.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 1618-1624
    • Chan, J.L.1    Bullen, J.2    Stoyneva, V.3
  • 37
    • 1942440850 scopus 로고    scopus 로고
    • Leptin and the proinflammatory state associated with human obesity
    • Hukshorn CJ, Lindeman JH, Toet KH, et al. Leptin and the proinflammatory state associated with human obesity. J Clin Endocrinol Metab 2004; 89: 1773-1778.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 1773-1778
    • Hukshorn, C.J.1    Lindeman, J.H.2    Toet, K.H.3
  • 38
    • 33646204903 scopus 로고    scopus 로고
    • Allelic spectrum of the natural variation in CRP
    • Crawford DC, Yi Q, Smith JD, et al. Allelic spectrum of the natural variation in CRP. Hum Genet 2006; 119: 496-504.
    • (2006) Hum Genet , vol.119 , pp. 496-504
    • Crawford, D.C.1    Yi, Q.2    Smith, J.D.3
  • 39
    • 33749857774 scopus 로고    scopus 로고
    • Genetic variations of the endothelial nitric oxide synthase gene are related to increased levels of C-reactive protein and macrophage-colony stimulating-factor in patients with coronary artery disease
    • Lekakis JP, Ikonomidis I, Tsibida M, et al. Genetic variations of the endothelial nitric oxide synthase gene are related to increased levels of C-reactive protein and macrophage-colony stimulating-factor in patients with coronary artery disease. Thromb Haemost 2006; 96: 520-528.
    • (2006) Thromb Haemost , vol.96 , pp. 520-528
    • Lekakis, J.P.1    Ikonomidis, I.2    Tsibida, M.3
  • 40
    • 0141957373 scopus 로고    scopus 로고
    • IL1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals
    • Eklund C, Jahan F, Pessi T, et al. IL1B gene polymorphism is associated with baseline C-reactive protein levels in healthy individuals. Eur Cytokine Netw 2003; 14: 168-171
    • (2003) Eur Cytokine Netw , vol.14 , pp. 168-171
    • Eklund, C.1    Jahan, F.2    Pessi, T.3
  • 41
    • 0347917232 scopus 로고    scopus 로고
    • Polymorphism at the C-reactive protein locus nfluences gene expression and predisposes to systemic lupus erythematosus
    • Russell AI, Cunninghame Graham DS, Shepherd C, et al. Polymorphism at the C-reactive protein locus nfluences gene expression and predisposes to systemic lupus erythematosus. Hum Mol Genet 2004; 13: 137-147.
    • (2004) Hum Mol Genet , vol.13 , pp. 137-147
    • Russell, A.I.1    Cunninghame Graham, D.S.2    Shepherd, C.3
  • 42
    • 33845491101 scopus 로고    scopus 로고
    • Association of polymorphisms in the CRP gene with circuating C-reactive protein levels and cardiovascular events
    • Lange LA, Carlson CS, Hindorff LA, et al. Association of polymorphisms in the CRP gene with circuating C-reactive protein levels and cardiovascular events. J Am Med Assoc 2006, 296: 2703-2711.
    • (2006) J Am Med Assoc , vol.296 , pp. 2703-2711
    • Lange, L.A.1    Carlson, C.S.2    Hindorff, L.A.3


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