Induction of group VIA phospholipase A2 activity during in vitro ischemia in C2C12 myotubes is associated with changes in the level of its splice variants

American Journal of Physiology - Cell Physiology

Volumn 293, Issue 5, 2007, Pages

  Poulsen, K A ^a   Pedersen, S F ^a   Kolko, M ^b   Lambert, I H ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b Eye Pathology Institute   (Denmark)

Author keywords

Ca2+ independent phospholipase A2 ; Ca2+ independent phospholipase A2 ; Hypoxia

Indexed keywords

BROMOENOL LACTONE; CALCIUM INDEPENDENT PHOSPHOLIPASE A2 BETA; CALCIUM INDEPENDENT PHOSPHOLIPASE A2 GAMMA; CALCIUM INDEPENDENT PHOSPHOLIPASE A2 VIA; GLUCOSE; ISOENZYME; OXYGEN; PHOSPHOLIPASE A2; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CATALYSIS; CELL STRAIN; CELL VIABILITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME INHIBITION; IN VITRO STUDY; MOLECULAR WEIGHT; MOUSE; MUSCLE ISCHEMIA; MYOTUBE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

ANIMALS; ARACHIDONIC ACIDS; CELL HYPOXIA; CELL LINE; CELL SURVIVAL; ENDOPLASMIC RETICULUM; ENZYME INDUCTION; GLUCOSE; GROUP IV PHOSPHOLIPASES A2; ISCHEMIA; MICE; MOLECULAR WEIGHT; MUSCLE FIBERS; MUSCLE, SKELETAL; NAPHTHALENES; PHOSPHODIESTERASE INHIBITORS; PROTEIN ISOFORMS; PYRONES; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 36048952649     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00012.2007     Document Type: Article

References (62)

1. 2+-independent cytosolic phospholipase A2 from macrophage-like P388D1 cells. Isolation and characterization. J Biol Chem 269: 9227-9233, 1994.
2. 2 in ischemia/reperfusion-induced damage in HL-1 mouse cardiomyocytes (Abstract). FASEB J 21: A684, 2007.
3. Arai K, Ikegaya Y, Nakatani Y, Kudo I, Nishiyama N, Matsuki N. Phospholipase A2 mediates ischemic injury in the hippocampus: a regional difference of neuronal vulnerability. Eur J Neurosci 13: 2319-2323, 2001.
4. 2+-independent phospholipase A2 but not cytosolic phospholipase A2, which undergoes proteolytic inactivation. J Biol Chem 273: 13870-13877, 1998.
5. Balboa MA, Balsinde J. Involvement of calcium-independent phospholipase A2 in hydrogen peroxide-induced accumulation of free fatty acids in human U937 cells. J Biol Chem 277: 40384-40389, 2002.
6. Balsinde J. Roles of various phospholipases A2 in providing lysophospholipid acceptors for fatty acid phospholipid incorporation and remodelling. Biochem J 364: 695-702, 2002.
7. Balsinde J, Bianco ID, Ackermann EJ, Conde-Frieboes K, Dennis EA. Inhibition of calcium-independent phospholipase A2 prevents arachidonic acid incorporation and phospholipid remodeling in P388D1 macrophages. Proc Natl Acad Sci USA 92: 8527-8531, 1995.
8. Bao S, Bohrer A, Ramanadham S, Jin W, Zhang S, Turk J. Effects of stable suppression of group VIA phospholipase A2 expression on phospholipid content and composition, insulin secretion, and proliferation of INS-1 insulinoma cells. J Biol Chem 281: 187-198, 2006.
9. 2β movements in response to stimulation with insulin secretagogues in INS-1 cells. Diabetes 53, Suppl 1: S186-S189, 2004.
10. 2 in uterine stromal cells. Biochem Biophys Res Commun 276: 613-618, 2000.
11. 2+-independent degradation of mitochondrial phospholipids. Biochemistry 41: 7771-7780, 2002.
12. Brustovetsky T, Antonsson B, Jemmerson R, Dubinsky JM, Brustovetsky N. Activation of calcium-independent phospholipase A (iPLA) in brain mitochondria and release of apoptogenic factors by BAX and truncated BID. J Neurochem 94: 980-994, 2005.
13. Caro AA, Cederbaum AI. Role of cytochrome P450 in phospholipase A2- and arachidonic acid-mediated cytotoxicity. Free Radic Biol Med 40: 364-375, 2006.
14. Carvalho AJ, McKee NH, Green HJ. Metabolic and contractile responses of fast and slow twitch rat skeletal muscles to ischemia and reperfusion. Plast Reconstr Surg 99: 163-171, 1997.
15. 2) in phosphatidylcholine metabolism. Biochem Biophys Res Commun 287: 600-606, 2001.
16. 2+-independent phospholipase A2 in renal cells during oxidative stress. J Am Soc Nephrol 15: 1441-1451, 2004.
17. 2s in cell injury and death. J Pharmacol Exp Ther 294: 793-799, 2000.
18. 2+-independent phospholipase A2 in oxidant-induced renal cell death. Am J Physiol Renal Physiol 283: F492-F498, 2002.
19. 2+-independent phospholipase A2 in cisplatin-induced renal cell apoptosis. J Pharmacol Exp Ther 308: 921-928, 2004.
20. Farooqui AA, Horrocks LA, Farooqui T. Deacylation and reacylation of neural membrane glycerophospholipids. J Mol Neurosci 14: 123-135, 2000.
21. Ford DA, Hazen SL, Saffitz JE, Gross RW. The rapid and reversible activation of a calcium-independent plasmalogen-selective phospholipase A2 during myocardial ischemia. J Clin Invest 88: 331-335, 1991.
22. 2+ influx and loss of cell membrane integrity in rat extensor digitorum longus muscle. Exp Physiol 90: 703-714, 2005.
23. Gadd ME, Broekemeier KM, Crouser ED, Kumar J, Graff G, Pfeiffer DR. Mitochondrial iPLA2 activity modulates the release of cytochrome c from mitochondria and influences the permeability transition. J Biol Chem 281: 6931-6939, 2006.
24. Haugstetter J, Blicher T, Ellgaard L. Identification and characterization of a novel thioredoxin-related transmembrane protein of the endoplasmic reticulum. J Biol Chem 280: 8371-8380, 2005.
25. Hazen SL, Ford DA, Gross RW. Activation of a membrane-associated phospholipase A2 during rabbit myocardial ischemia which is highly selective for plasmalogen substrate. J Biol Chem 266: 5629-5633, 1991.
26. Jenkins CM, Mancuso DJ, Yan W, Sims HF, Gibson B, Gross RW. Identification, cloning, expression, and purification of three novel human calcium-independent phospholipase A2 family members possessing triacylglycerol lipase and acylglycerol transacylase activities. J Biol Chem 279: 48968-48975, 2004.
27. 2γ in mitochondria and its role in mitochondrial oxidative stress. Am J Physiol Renal Physiol 292: F853-F860, 2007.
28. Kudo I, Murakami M. Phospholipase A2 enzymes. Prostaglandins Other Lipid Mediat 68-69: 3-58, 2002.
29. Lambert IH. Reactive oxygen species regulate swelling-induced taurine efflux in NIH3T3 mouse fibroblasts. J Membr Biol 192: 19-32, 2003.
30. Lambert IH, Nielsen JH, Andersen HJ, Ortenblad N. Cellular model for induction of drip loss in meat. J Agric Food Chem 49: 4876-4883, 2001.
31. Lambert IH, Pedersen SF, Poulsen KA. Activation of PLA2 isoforms by cell swelling and ischaemia/hypoxia. Acta Physiol (Oxf) 187: 75-85, 2006.
32. Larsson Forsell PK, Kennedy BP, Claesson HE. The human calcium-independent phospholipase A2 gene multiple enzymes with distinct properties from a single gene. Eur J Biochem 262: 575-585, 1999.
33. Larsson PK, Claesson HE, Kennedy BP. Multiple splice variants of the human calcium-independent phospholipase A2 and their effect on enzyme activity. J Biol Chem 273: 207-214, 1998.
34. Lei X, Zhang S, Bohrer A, Bao S, Song H, Ramanadham S. The group VIA calcium-independent phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase. Biochemistry 46: 10170-10185, 2007.
35. Liou JY, Aleksic N, Chen SF, Han TJ, Shyue SK, Wu KK. Mitochondrial localization of cyclooxygenase-2 and calcium-independent phospholipase A2 in human cancer cells: implication in apoptosis resistance. Exp Cell Res 306: 75-84, 2005.
36. Mancuso DJ, Abendschein DR, Jenkins CM, Han X, Saffitz JE, Schuessler RB, Gross RW. Cardiac ischemia activates calcium-independent phospholipase A2beta, precipitating ventricular tachyarrhythmias in transgenic mice: rescue of the lethal electrophysiologic phenotype by mechanism-based inhibition. J Biol Chem 278: 22231-22236, 2003.
37. 2. J Biol Chem 275: 9937-9945, 2000.
38. Mancuso DJ, Jenkins CM, Sims HF, Cohen JM, Yang J, Gross RW. Complex transcriptional and translational regulation of iPLAgamma resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization. Eur J Biochem 271: 4709-4724, 2004.
39. Manguikian AD, Barbour SE. Cell cycle dependence of group VIA calcium-independent phospholipase A2 activity. J Biol Chem 279: 52881-52892, 2004.
40. 2+-independent phospholipase A2 on arachidonic acid release induced by reactive oxygen species. Arch Biochem Biophys 392: 257-262, 2001.
41. McHowat J, Creer MH. Catalytic features, regulation and function of myocardial phospholipase A2. Curr Med Chem Cardiovasc Hematol Agents 2: 209-218, 2004.
42. 2. Cancer Res 61: 4024-4029, 2001.
43. Miyake R, Gross RW. Multiple phospholipase A2 activities in canine vascular smooth muscle. Biochim Biophys Acta 1165: 167-176, 1992.
44. 2+-independent phospholipase A2gamma promotes cellular membrane hydrolysis and prostaglandin production in a manner distinct from other intracellular phospholipases A2. J Biol Chem 280: 14028-14041, 2005.
45. Pedersen SF, Poulsen KA, Lambert IH. Roles of phospholipase A2 isoforms in the swelling- and melittin-induced arachidonic acid release and taurine efflux in NIH3T3 fibroblasts. Am J Physiol Cell Physiol 291: C1286-C1296, 2006.
46. Perez R, Melero R, Balboa MA, Balsinde J. Role of group VIA calcium-independent phospholipase A2 in arachidonic acid release, phospholipid fatty acid incorporation, and apoptosis in U937 cells responding to hydrogen peroxide. J Biol Chem 279: 40385-40391, 2004.
47. Phillis JW, O'Regan MH. A potentially critical role of phospholipases in central nervous system ischemic, traumatic, and neurodegenerative disorders. Brain Res Brain Res Rev 44: 13-47, 2004.
48. Portilla D, Shah SV, Lehman PA, Creer MH. Role of cytosolic calcium-independent plasmalogen-selective phospholipase A2 in hypoxic injury to rabbit proximal tubules. J Clin Invest 93: 1609-1615, 1994.
49. Sanchez T, Moreno JJ. Calcium-independent phospholipase A2 through arachidonic acid mobilization is involved in Caco-2 cell growth. J Cell Physiol 193: 293-298, 2002.
50. Sapirstein A, Bonventre JV. Phospholipases A2 in ischemic and toxic brain injury. Neurochem Res 25: 745-753, 2000.
51. Seleznev K, Zhao C, Zhang XH, Song K, Ma ZA. Calcium-independent phospholipase A2 localizes in and protects mitochondria during apoptotic induction by staurosporine. J Biol Chem 281: 22275-22288, 2006.
52. Shinzawa K, Tsujimoto Y. PLA2 activity is required for nuclear shrinkage in caspase-independent cell death. J Cell Biol 163: 1219-1230, 2003.
53. Smani T, Zakharov SI, Csutora P, Leno E, Trepakova ES, Bolotina VM. A novel mechanism for the store-operated calcium influx pathway. Nat Cell Biol 6: 113-120, 2004.
54. Su X, Mancuso DJ, Bickel PE, Jenkins CM, Gross RW. Small interfering RNA knockdown of calcium-independent phospholipases A2 beta or gamma inhibits the hormone-induced differentiation of 3T3-L1 preadipocytes. J Biol Chem 279: 21740-21748, 2004.
55. Swift L, McHowat J, Sarvazyan N. Inhibition of membrane-associated calcium-independent phospholipase A2 as a potential culprit of anthracycline cardiotoxicity. Cancer Res 63: 5992-5998, 2003.
56. 2. Biochem Biophys Res Commun 272: 320-326, 2000.
57. Tang J, Kriz RW, Wolfman N, Shaffer M, Seehra J, Jones SS. A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs. J Biol Chem 272: 8567-8575, 1997.
58. Turk J, Ramanadham S. The expression and function of a group VIA calcium-independent phospholipase A2 (iPLA2beta) in beta-cells. Can J Physiol Pharmacol 82: 824-832, 2004.
59. van Tienhoven M, Atkins J, Li Y, Glynn P. Human neuropathy target esterase catalyzes hydrolysis of membrane lipids. J Biol Chem 277: 20942-20948, 2002.
60. Wang Z, Ramanadham S, Ma ZA, Bao S, Mancuso DJ, Gross RW, Turk J. Group VIA phospholipase A2 forms a signaling complex with the calcium/calmodulin-dependent protein kinase IIbeta expressed in pancreatic islet beta-cells. J Biol Chem 280: 6840-6849, 2005.
61. Williams SD, Gottlieb RA. Inhibition of mitochondrial calcium-independent phospholipase A2 (iPLA2) attenuates mitochondrial phospholipid loss and is cardioprotective. Biochem J 362: 23-32, 2002.
62. Williams SD, Hsu FF, Ford DA. Electrospray ionization mass spectrometry analyses of nuclear membrane phospholipid loss after reperfusion of ischemic myocardium. J Lipid Res 41: 1585-1595, 2000.