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Volumn 150, Issue 3, 2007, Pages 509-517

Altered CD45 isoform expression in C77G carriers influences cytokine responsiveness and adhesion properties of T cells

Author keywords

C77G polymorphism; CD45; Multiple sclerosis; T cell reactivity

Indexed keywords

CD45 ANTIGEN; CYTOKINE; INTERLEUKIN 2; JANUS KINASE 1; T LYMPHOCYTE RECEPTOR;

EID: 36048945330     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/j.1365-2249.2007.03508.x     Document Type: Article
Times cited : (16)

References (33)
  • 1
    • 0038815306 scopus 로고    scopus 로고
    • CD45: A critical regulator of signaling thresholds in immune cells
    • Hermiston ML, Xu Z, Weiss A. CD45: a critical regulator of signaling thresholds in immune cells. Annu Rev Immunol 2003 21 : 107 37.
    • (2003) Annu Rev Immunol , vol.21 , pp. 107-37
    • Hermiston, M.L.1    Xu, Z.2    Weiss, A.3
  • 2
    • 0035905767 scopus 로고    scopus 로고
    • CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling
    • Irie-Sasaki J, Sasaki T, Matsumoto W et al. CD45 is a JAK phosphatase and negatively regulates cytokine receptor signalling. Nature 2001 409 : 349 54.
    • (2001) Nature , vol.409 , pp. 349-54
    • Irie-Sasaki, J.1    Sasaki, T.2    Matsumoto, W.3
  • 3
    • 0033564326 scopus 로고    scopus 로고
    • Regulation of integrin-mediated T cell adhesion by the transmembrane protein tyrosine phosphatase CD45
    • Shenoi H, Seavitt J, Zheleznyak A, Thomas ML, Brown EJ. Regulation of integrin-mediated T cell adhesion by the transmembrane protein tyrosine phosphatase CD45. J Immunol 1999 162 : 7120 7.
    • (1999) J Immunol , vol.162 , pp. 7120-7
    • Shenoi, H.1    Seavitt, J.2    Zheleznyak, A.3    Thomas, M.L.4    Brown, E.J.5
  • 4
    • 0023636055 scopus 로고
    • Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens
    • Streuli M, Hall LR, Saga Y, Schlossman SF, Saito H. Differential usage of three exons generates at least five different mRNAs encoding human leukocyte common antigens. J Exp Med 1987 166 : 1548 66.
    • (1987) J Exp Med , vol.166 , pp. 1548-66
    • Streuli, M.1    Hall, L.R.2    Saga, Y.3    Schlossman, S.F.4    Saito, H.5
  • 5
    • 33644557158 scopus 로고    scopus 로고
    • Altered CD45 expression and disease
    • Tchilian EZ, Beverley PC. Altered CD45 expression and disease. Trends Immunol 2006 27 : 146 53.
    • (2006) Trends Immunol , vol.27 , pp. 146-53
    • Tchilian, E.Z.1    Beverley, P.C.2
  • 6
    • 19544394235 scopus 로고    scopus 로고
    • Disease associations and altered immune function in CD45 138G variant carriers
    • Boxall S, Stanton T, Hirai K et al. Disease associations and altered immune function in CD45 138G variant carriers. Hum Mol Genet 2004 13 : 2377 84.
    • (2004) Hum Mol Genet , vol.13 , pp. 2377-84
    • Boxall, S.1    Stanton, T.2    Hirai, K.3
  • 7
    • 0029067113 scopus 로고
    • A point mutation in the human CD45 gene associated with defective splicing of exon a
    • Thude H, Hundrieser J, Wonigeit K, Schwinzer R. A point mutation in the human CD45 gene associated with defective splicing of exon A. Eur J Immunol 1995 25 : 2101 6.
    • (1995) Eur J Immunol , vol.25 , pp. 2101-6
    • Thude, H.1    Hundrieser, J.2    Wonigeit, K.3    Schwinzer, R.4
  • 8
    • 0035968259 scopus 로고    scopus 로고
    • A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer
    • Lynch KW, Weiss A. A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. J Biol Chem 2001 276 : 24341 7.
    • (2001) J Biol Chem , vol.276 , pp. 24341-7
    • Lynch, K.W.1    Weiss, A.2
  • 9
    • 0036198406 scopus 로고    scopus 로고
    • A CD45 polymorphism associated with abnormal splicing is absent in African populations
    • Tchilian EZ, Dawes R, Ramaley PA et al. A CD45 polymorphism associated with abnormal splicing is absent in African populations. Immunogenetics 2002 53 : 980 3.
    • (2002) Immunogenetics , vol.53 , pp. 980-3
    • Tchilian, E.Z.1    Dawes, R.2    Ramaley, P.A.3
  • 10
    • 0033662317 scopus 로고    scopus 로고
    • A point mutation in PTPRC (CD45) is associated with the development of multiple sclerosis
    • Jacobsen M, Schweer D, Ziegler A et al. A point mutation in PTPRC (CD45) is associated with the development of multiple sclerosis. Nat Genet 2000 26 : 495 9.
    • (2000) Nat Genet , vol.26 , pp. 495-9
    • Jacobsen, M.1    Schweer, D.2    Ziegler, A.3
  • 11
    • 0037119252 scopus 로고    scopus 로고
    • Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population
    • Ballerini C, Rosati E, Salvetti M et al. Protein tyrosine phosphatase receptor-type C exon 4 gene mutation distribution in an Italian multiple sclerosis population. Neurosci Lett 2002 328 : 325 7.
    • (2002) Neurosci Lett , vol.328 , pp. 325-7
    • Ballerini, C.1    Rosati, E.2    Salvetti, M.3
  • 12
    • 0345039852 scopus 로고    scopus 로고
    • Does 77C→G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus?
    • Vorechovsky I, Kralovicova J, Tchilian E et al. Does 77C→G in PTPRC modify autoimmune disorders linked to the major histocompatibility locus? Nat Genet 2001 29 : 22 4.
    • (2001) Nat Genet , vol.29 , pp. 22-4
    • Vorechovsky, I.1    Kralovicova, J.2    Tchilian, E.3
  • 13
    • 17944365032 scopus 로고    scopus 로고
    • PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients
    • Barcellos LF, Caillier S, Dragone L et al. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nat Genet 2001 29 : 23 4.
    • (2001) Nat Genet , vol.29 , pp. 23-4
    • Barcellos, L.F.1    Caillier, S.2    Dragone, L.3
  • 14
    • 0038777806 scopus 로고    scopus 로고
    • Enhanced frequency of a PTPRC (CD45) exon a mutation (77C→G) in systemic sclerosis
    • Schwinzer R, Witte T, Hundrieser J et al. Enhanced frequency of a PTPRC (CD45) exon A mutation (77C→G) in systemic sclerosis. Genes Immun 2003 4 : 168 9.
    • (2003) Genes Immun , vol.4 , pp. 168-9
    • Schwinzer, R.1    Witte, T.2    Hundrieser, J.3
  • 15
    • 0038805136 scopus 로고    scopus 로고
    • 77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: Evidence for a genetic link
    • Vogel A, Strassburg CP, Manns MP. 77 C/G mutation in the tyrosine phosphatase CD45 gene and autoimmune hepatitis: evidence for a genetic link. Genes Immun 2003 4 : 79 81.
    • (2003) Genes Immun , vol.4 , pp. 79-81
    • Vogel, A.1    Strassburg, C.P.2    Manns, M.P.3
  • 16
    • 33747060756 scopus 로고    scopus 로고
    • Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection
    • Dawes R, Hennig B, Irving W et al. Altered CD45 expression in C77G carriers influences immune function and outcome of hepatitis C infection. J Med Genet 2006 43 : 678 84.
    • (2006) J Med Genet , vol.43 , pp. 678-84
    • Dawes, R.1    Hennig, B.2    Irving, W.3
  • 17
    • 0035964663 scopus 로고    scopus 로고
    • A point mutation in CD45 may be associated with an enhanced risk of HIV-1 infection
    • Tchilian EZ, Wallace DL, Dawes R et al. A point mutation in CD45 may be associated with an enhanced risk of HIV-1 infection. AIDS 2001 15 : 1892 4.
    • (2001) AIDS , vol.15 , pp. 1892-4
    • Tchilian, E.Z.1    Wallace, D.L.2    Dawes, R.3
  • 18
    • 10744224548 scopus 로고    scopus 로고
    • Abnormal cell surface antigen expression in individuals with variant CD45 splicing and histiocytosis
    • Boxall S, Mccormick J, Beverley P et al. Abnormal cell surface antigen expression in individuals with variant CD45 splicing and histiocytosis. Pediatr Res 2004 55 : 478 84.
    • (2004) Pediatr Res , vol.55 , pp. 478-84
    • Boxall, S.1    McCormick, J.2    Beverley, P.3
  • 19
    • 0036169347 scopus 로고    scopus 로고
    • CD45 exon 4 point mutation does not confer susceptibility to type 1 diabetes mellitus or Graves' disease
    • Wood JP, Bieda K, Segni M et al. CD45 exon 4 point mutation does not confer susceptibility to type 1 diabetes mellitus or Graves' disease. Eur J Immunogenet 2002 29 : 73 4.
    • (2002) Eur J Immunogenet , vol.29 , pp. 73-4
    • Wood, J.P.1    Bieda, K.2    Segni, M.3
  • 20
    • 9644279857 scopus 로고    scopus 로고
    • A transmembrane protein-tyrosine phosphatase receptor type C (CD45) exon a point mutation (77 C to G) is not associated with the development of type 1 diabetes mellitus in a German population
    • Thude H, Rosenhahn S, Hunger-Dathe W, Muller UA, Barz D. A transmembrane protein-tyrosine phosphatase receptor type C (CD45) exon A point mutation (77 C to G) is not associated with the development of type 1 diabetes mellitus in a German population. Eur J Immunogenet 2004 31 : 245 7.
    • (2004) Eur J Immunogenet , vol.31 , pp. 245-7
    • Thude, H.1    Rosenhahn, S.2    Hunger-Dathe, W.3    Muller, U.A.4    Barz, D.5
  • 21
    • 2542489475 scopus 로고    scopus 로고
    • PTPRC (CD45) is not associated with multiple sclerosis in a large cohort of German patients
    • Miterski B, Sindern E, Haupts M, Schimrigk S, Epplen J. PTPRC (CD45) is not associated with multiple sclerosis in a large cohort of German patients. BMC Med Genet 2002 3 : 3.
    • (2002) BMC Med Genet , vol.3 , pp. 3
    • Miterski, B.1    Sindern, E.2    Haupts, M.3    Schimrigk, S.4    Epplen, J.5
  • 22
    • 23044440242 scopus 로고    scopus 로고
    • C77G mutation in protein tyrosine phosphatase CD45 gene and autoimmune hepatitis
    • Esteghamat F, Noorinayer B, Sanati MH et al. C77G mutation in protein tyrosine phosphatase CD45 gene and autoimmune hepatitis. Hepatol Res 2005 32 : 154 7.
    • (2005) Hepatol Res , vol.32 , pp. 154-7
    • Esteghamat, F.1    Noorinayer, B.2    Sanati, M.H.3
  • 23
    • 30744434634 scopus 로고    scopus 로고
    • The 77C→G mutation in the human CD45 (PTPRC) gene leads to increased intensity of TCR signaling in T cell lines from healthy individuals and patients with multiple sclerosis
    • Do HT, Baars W, Borns K, Windhagen A, Schwinzer R. The 77C→G mutation in the human CD45 (PTPRC) gene leads to increased intensity of TCR signaling in T cell lines from healthy individuals and patients with multiple sclerosis. J Immunol 2006 176 : 931 8.
    • (2006) J Immunol , vol.176 , pp. 931-8
    • Do, H.T.1    Baars, W.2    Borns, K.3    Windhagen, A.4    Schwinzer, R.5
  • 24
    • 0036184261 scopus 로고    scopus 로고
    • Interferon-β increases the stimulatory capacity of monocyte-derived dendritic cells to induce IL-13, IL-5, and IL-10 in autologous T-cells
    • Wiesemann E, Sönmez D, Heidenreich F, Windhagen A. Interferon-β increases the stimulatory capacity of monocyte-derived dendritic cells to induce IL-13, IL-5, and IL-10 in autologous T-cells. J Neuroimmunol 2002 123 : 160 9.
    • (2002) J Neuroimmunol , vol.123 , pp. 160-9
    • Wiesemann, E.1    Sönmez, D.2    Heidenreich, F.3    Windhagen, A.4
  • 25
    • 0027419878 scopus 로고
    • CD45 mAb induces cell adhesion in peripheral blood mononuclear cells via lymphocyte function-associated antigen-1 (LFA-1) and intercellular cell adhesion molecule 1 (ICAM-1)
    • Lorenz HM, Harrer T, Lagoo AS, Baur A, Eger G, Kalden JR. CD45 mAb induces cell adhesion in peripheral blood mononuclear cells via lymphocyte function-associated antigen-1 (LFA-1) and intercellular cell adhesion molecule 1 (ICAM-1). Cell Immunol 1993 147 : 110 28.
    • (1993) Cell Immunol , vol.147 , pp. 110-28
    • Lorenz, H.M.1    Harrer, T.2    Lagoo, A.S.3    Baur, A.4    Eger, G.5    Kalden, J.R.6
  • 26
    • 33646587386 scopus 로고    scopus 로고
    • CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells
    • Piercy J, Petrova S, Tchilian EZ, Beverley PC. CD45 negatively regulates tumour necrosis factor and interleukin-6 production in dendritic cells. Immunology 2006 118 : 250 6.
    • (2006) Immunology , vol.118 , pp. 250-6
    • Piercy, J.1    Petrova, S.2    Tchilian, E.Z.3    Beverley, P.C.4
  • 27
    • 16244366828 scopus 로고    scopus 로고
    • Functional significance of the 77C→G polymorphism in the human CD45 gene: Enhanced T-cell reactivity by variantly expressed CD45RA isoforms
    • Do HT, Baars W, Schwinzer R. Functional significance of the 77C→G polymorphism in the human CD45 gene: enhanced T-cell reactivity by variantly expressed CD45RA isoforms. Transplant Proc 2005 37 : 51 2.
    • (2005) Transplant Proc , vol.37 , pp. 51-2
    • Do, H.T.1    Baars, W.2    Schwinzer, R.3
  • 30
    • 0031441901 scopus 로고    scopus 로고
    • Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling
    • 3rd
    • Petricoin EF 3rd, Ito S, Williams BL et al. Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling. Nature 1997 390 : 629 32.
    • (1997) Nature , vol.390 , pp. 629-32
    • Petricoin, E.F.1    Ito, S.2    Williams, B.L.3
  • 31
    • 0031172246 scopus 로고    scopus 로고
    • CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion
    • Roach T, Slater S, Koval M et al. CD45 regulates Src family member kinase activity associated with macrophage integrin-mediated adhesion. Curr Biol 1997 7 : 408 17.
    • (1997) Curr Biol , vol.7 , pp. 408-17
    • Roach, T.1    Slater, S.2    Koval, M.3
  • 32
    • 0030589324 scopus 로고    scopus 로고
    • CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion
    • Herold C, Elhabazi A, Bismuth G, Bensussan A, Boumsell L. CD100 is associated with CD45 at the surface of human T lymphocytes. Role in T cell homotypic adhesion. J Immunol 1996 157 : 5262 8.
    • (1996) J Immunol , vol.157 , pp. 5262-8
    • Herold, C.1    Elhabazi, A.2    Bismuth, G.3    Bensussan, A.4    Boumsell, L.5
  • 33
    • 0027936858 scopus 로고
    • Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase
    • Arroyo AG, Campanero MR, Sanchez-Mateos P et al. Induction of tyrosine phosphorylation during ICAM-3 and LFA-1-mediated intercellular adhesion, and its regulation by the CD45 tyrosine phosphatase. J Cell Biol 1994 126 : 1277 86.
    • (1994) J Cell Biol , vol.126 , pp. 1277-86
    • Arroyo, A.G.1    Campanero, M.R.2    Sanchez-Mateos, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.