A CD45 polymorphism associated with abnormal splicing is absent in African populations

Immunogenetics

Volumn 53, Issue 10-11, 2002, Pages 980-983

  Tchilian, Elma Z ^{a,b,c,d,e,f,g,h,i}   Dawes, Ritu ^{a,b,c,d,e,f,g,h,i}   Ramaley, Patricia A ^{a,b,c,d,e,f,g,h,i}   Whitworth, James A ^{a,b,c,d,e,f,g,h,i}   Yuldasheva, Nadira ^{a,b,c,d,e,f,g,h,i}   Wells, Spencer R ^{a,b,c,d,e,f,g,h,i}   Watera, Christine ^{a,b,c,d,e,f,g,h,i}   French, Neil ^{a,b,c,d,e,f,g,h,i}   Gilks, Charles F ^{a,b,c,d,e,f,g,h,i}   Kunachiwa, Warunee ^{a,b,c,d,e,f,g,h,i}   Ruzibakiev, Ruslan ^{a,b,c,d,e,f,g,h,i}   Leetrakool, Nipapan ^{a,b,c,d,e,f,g,h,i}   Carrington, Christine V ^{a,b,c,d,e,f,g,h,i}   Ramdath, Dan D ^{a,b,c,d,e,f,g,h,i}   Gotch, Frances ^{a,b,c,d,e,f,g,h,i}   Stephens, Henry A ^{a,b,c,d,e,f,g,h,i}   Hill, Adrian V ^{a,b,c,d,e,f,g,h,i}   Beverley, Peter C ^{a,b,c,d,e,f,g,h,i}  

^a EDWARD JENNER INST FOR VACC RES   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UGANDA VIRUS RESEARCH INSTITUTE   (Uganda)

^d LIVERPOOL SCHOOL OF TROPICAL MEDICINE   (United Kingdom)

^e CHIANG MAI UNIVERSITY   (Thailand)

^f S YU YUNUSOV INSTITUTE OF THE CHEMISTRY OF PLANT SUBSTANCES   (Uzbekistan)

^g UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

^h CHELSEA AND WESTMINSTER HOSPITAL   (United Kingdom)

ⁱ INSTITUTE OF UROLOGY AND NEPHROLOGY   (United Kingdom)

Author keywords

CD45; Humans; Polymorphism; PTPRC; Splicing

Indexed keywords

CD45 ANTIGEN;

AFRICA; ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOGENETICS; MAJOR CLINICAL STUDY; MULTIPLE SCLEROSIS; PRIORITY JOURNAL; RNA SPLICING;

AFRICA; AFRICAN CONTINENTAL ANCESTRY GROUP; ALTERNATIVE SPLICING; ANTIGENS, CD45; ASIA, CENTRAL; ASIAN CONTINENTAL ANCESTRY GROUP; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; EXONS; FEMALE; GENE FREQUENCY; HUMANS; MALE; POLYMORPHISM, GENETIC;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0036198406     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-001-0410-z     Document Type: Article

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2. Cord blood apolipoprotein-E genotype distribution and plasma lipid indices in newborns of different ethnicity
3. Abnormal T-cell phenotype in familial erythrophagocytic lymphohistiocytosis
4. CD45-null transgenic mice reveal a positive regulatory role for CD45 in early thymocyte development, in the selection of CD4+CD8+ thymocytes, and B cell maturation
5. Genomic structure and sequence of the leukocyte common antigen (CD45) from the pufferfish Fugu rubripes and comparison with its mammalian homologue
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7. A point mutation in PTPRC is associated with the development of multiple sclerosis
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9. T cell development in mice expressing splice variants of the protein tyrosine phosphatase CD45
10. Mutations in the tyrosine phosphatase CD45 gene in a child with severe combined immunodeficiency disease
11. An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity
12. Global distribution of the CCR5 gene 32-basepair deletion
13. CD45: New jobs for an old acquaintance
14. Genetic basis of antigenic differences between three alleles of Ly5 (CD45) in mice
15. Genetically determined lack of CD45R- T cells in healthy individuals. Evidence for a regulatory polymorphism of CD45R antigen expression
16. Molecular basis of antigenic differences between the RT7 alleles of rat CD45
17. A deletion in the gene encoding the CD45 antigen in a patient with SCID
18. A point mutation in CD45 may be associated with HIV-1 infection
19. The exon A (C77G) mutation is a common cause of abnormal CD45 splicing in humans
20. A point mutation in the human CD45 gene associated with defective splicing of exon A
21. Is the 77C-G transversion in PTPRC a genetic modifier of major histocompatibility complex-linked autoimmune disorders?
22. A prospective study of CD45 isoform expression in haemophagocytic lymphohistiocytosis; an abnormal inherited immunophenotype in one family
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