V-shaped structure of glutamyl-tRNA reductase, the first enzyme of tRNA-dependent tetrapyrrole biosynthesis

EMBO Journal

Volumn 20, Issue 23, 2001, Pages 6583-6590

  Moser, Jürgen ^a   Schubert, Wolf Dieter ^b   Beier, Viola ^b   Bringemeier, Ingo ^c   Jahn, Dieter ^a   Heinz, Dirk W ^b  

^a TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^b HELMHOLTZ CENTRE FOR INFECTION RESEARCH   (Germany)

^c Microsoft Germany Inc   (Germany)

Author keywords

Crystal structure; Glutamyl tRNA reductase; Metabolic channeling; Tetrapyrrole biosynthesis; tRNA

Indexed keywords

AMINOLEVULINIC ACID; CHLOROPHYLL; ENZYME INHIBITOR; GLUTAMATE 1 SEMIALDEHYDE 1,2 MUTASE; GLUTAMIC ACID DERIVATIVE; GLUTAMIC ACID TRANSFER RNA; GLUTAMIC ACID TRANSFER RNA REDUCTASE; GLUTAMYCIN; HEME DERIVATIVE; MUTASE; OXIDOREDUCTASE; PYRROLE DERIVATIVE; UNCLASSIFIED DRUG;

ARCHAEBACTERIUM; ARTICLE; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME STRUCTURE; ENZYME SUBSTRATE; METHANOBACTERIUM; NONHUMAN; PHYTOCHEMISTRY; PLANT; PRIORITY JOURNAL; PROKARYOTE;

ALDEHYDE OXIDOREDUCTASES; AMINOGLYCOSIDES; AMINOLEVULINIC ACID; AMINOPEPTIDASES; ANTI-BACTERIAL AGENTS; ARCHAEA; BINDING SITES; CATALYSIS; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; GLUTAMYL AMINOPEPTIDASE; INTRAMOLECULAR TRANSFERASES; MODELS, CHEMICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PYRROLES; RECOMBINANT PROTEINS; RNA, TRANSFER; SUBSTRATE SPECIFICITY; TETRAPYRROLES;

EID: 0035803598     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.23.6583     Document Type: Article

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