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Volumn 73, Issue 13, 2007, Pages 1389-1396

Characteristics of apoptosis induction by the alkaloid emetine in human tumour cell lines

Author keywords

Apoptosis; Bcl 2; Caspases; Emetine; p53 status; Proteomics

Indexed keywords

ALKALOID; CASPASE 3; CASPASE 6; CASPASE 8; CASPASE 9; EMETINE; LAMIN B; LAMIN B1; PLANT EXTRACT; PROTEIN BCL 2; PROTEIN P53; PSYCHOTRIA IPECACUANHA EXTRACT; UNCLASSIFIED DRUG;

EID: 36048933416     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-990229     Document Type: Article
Times cited : (27)

References (38)
  • 1
    • 9944222054 scopus 로고    scopus 로고
    • Exploiting death receptor signaling pathways for tumor therapy
    • Fulda S, Debatin KM. Exploiting death receptor signaling pathways for tumor therapy. Biochim Biophys Acta 2004; 1705: 27-41.
    • (2004) Biochim Biophys Acta , vol.1705 , pp. 27-41
    • Fulda, S.1    Debatin, K.M.2
  • 2
    • 0035525733 scopus 로고    scopus 로고
    • Cellular stress response and apoptosis in cancer therapy
    • Herr I, Debatin KM. Cellular stress response and apoptosis in cancer therapy. Blood 2001; 98: 2603-14.
    • (2001) Blood , vol.98 , pp. 2603-2614
    • Herr, I.1    Debatin, K.M.2
  • 3
    • 36049040984 scopus 로고    scopus 로고
    • Molecular modes of action of cytotoxic alkaloids - From DNA intercalation, spindle poisoning, topoisomerase inhibition to apoptosis and multiple drug resistance
    • Cordell G, editor, New York, London: Academic Press;
    • Wink M. Molecular modes of action of cytotoxic alkaloids - From DNA intercalation, spindle poisoning, topoisomerase inhibition to apoptosis and multiple drug resistance. In: Cordell G, editor. The Alkaloids New York, London: Academic Press; 2007: p xxxx.
    • (2007) The Alkaloids
    • Wink, M.1
  • 4
    • 36048996302 scopus 로고
    • An experimental study of the action of ipecacuanha on amoeba
    • Vedder EB. An experimental study of the action of ipecacuanha on amoeba. J Trop Med Hyg 1912; 15: 313-4.
    • (1912) J Trop Med Hyg , vol.15 , pp. 313-314
    • Vedder, E.B.1
  • 5
    • 3542991568 scopus 로고
    • Action of emetin on malignant tumors
    • Lewisohn R. Action of emetin on malignant tumors. JAMA 1918; 70: 9-10.
    • (1918) JAMA , vol.70 , pp. 9-10
    • Lewisohn, R.1
  • 6
    • 0015044608 scopus 로고
    • Experience with emetine hydrochloride (NSC 33 669) as an antitumor agent
    • Panettiere F, Coltman CA Jr. Experience with emetine hydrochloride (NSC 33 669) as an antitumor agent. Cancer 1971; 27: 835-41.
    • (1971) Cancer , vol.27 , pp. 835-841
    • Panettiere, F.1    Coltman Jr., C.A.2
  • 8
    • 0015741195 scopus 로고
    • Phase II study of emetine (NSC-33 669) in the treatment of solid tumors
    • Siddiqui S, Firat D, Olshin S. Phase II study of emetine (NSC-33 669) in the treatment of solid tumors. Cancer Chemother Rep 1973; 57: 423-8.
    • (1973) Cancer Chemother Rep , vol.57 , pp. 423-428
    • Siddiqui, S.1    Firat, D.2    Olshin, S.3
  • 10
    • 0015516197 scopus 로고
    • Cyclophosphamide plus emetine in lung cancer
    • Street EW. Cyclophosphamide plus emetine in lung cancer. Lancet 1972; 2: 381-2.
    • (1972) Lancet , vol.2 , pp. 381-382
    • Street, E.W.1
  • 11
    • 0015620235 scopus 로고
    • A phase I study of emetine hydrochloride (NSC 33669) in solid tumors
    • Mastrangelo MJ, Grage TB, Bellet RE, Weiss AJ. A phase I study of emetine hydrochloride (NSC 33669) in solid tumors. Cancer 1973; 31: 1170-5.
    • (1973) Cancer , vol.31 , pp. 1170-1175
    • Mastrangelo, M.J.1    Grage, T.B.2    Bellet, R.E.3    Weiss, A.J.4
  • 12
    • 0015644231 scopus 로고    scopus 로고
    • Bell DR. Treatment of amoebiasis. Trop Doct 1973; 3: 140-3.
    • Bell DR. Treatment of amoebiasis. Trop Doct 1973; 3: 140-3.
  • 13
    • 0019128876 scopus 로고
    • The chemotherapy of amoebiasis
    • Knight R. The chemotherapy of amoebiasis. J Antimicrob Chemother 1980; 6: 577-93.
    • (1980) J Antimicrob Chemother , vol.6 , pp. 577-593
    • Knight, R.1
  • 14
    • 0017374292 scopus 로고
    • Whatever happened to NSC? An analysis of clinical results of discontinued anticancer agents
    • Von Hoff DD, Rozencweig M, Soper WT. Whatever happened to NSC? An analysis of clinical results of discontinued anticancer agents. Cancer Treat Rep 1977; 61: 759-68.
    • (1977) Cancer Treat Rep , vol.61 , pp. 759-768
    • Von Hoff, D.D.1    Rozencweig, M.2    Soper, W.T.3
  • 15
    • 0015832031 scopus 로고
    • Inhibitors of protein synthesis in eukaryotes: Tools in cell research
    • Grollman AP, Huang MT. Inhibitors of protein synthesis in eukaryotes: tools in cell research. Fed Proc 1973; 32: 1673-8.
    • (1973) Fed Proc , vol.32 , pp. 1673-1678
    • Grollman, A.P.1    Huang, M.T.2
  • 16
    • 0001708009 scopus 로고
    • Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics
    • Grollman AP. Structural basis for inhibition of protein synthesis by emetine and cycloheximide based on an analogy between ipecac alkaloids and glutarimide antibiotics. Proc Natl Acad Sci USA 1966; 56: 1867-74.
    • (1966) Proc Natl Acad Sci USA , vol.56 , pp. 1867-1874
    • Grollman, A.P.1
  • 18
    • 0042823585 scopus 로고    scopus 로고
    • Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective
    • Wink M. Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective. Phytochemistry 2003; 64: 3-19.
    • (2003) Phytochemistry , vol.64 , pp. 3-19
    • Wink, M.1
  • 19
    • 0027265538 scopus 로고
    • DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis
    • Kochi SK, Collier RJ. DNA fragmentation and cytolysis in U937 cells treated with diphtheria toxin or other inhibitors of protein synthesis. Exp Cell Res 1993; 208: 296-302.
    • (1993) Exp Cell Res , vol.208 , pp. 296-302
    • Kochi, S.K.1    Collier, R.J.2
  • 20
    • 0027963422 scopus 로고
    • Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line U937
    • Bicknell GR, Snowden RT, Cohen GM. Formation of high molecular mass DNA fragments is a marker of apoptosis in the human leukaemic cell line U937. J Cell Sci 1994; 107: 2483-9.
    • (1994) J Cell Sci , vol.107 , pp. 2483-2489
    • Bicknell, G.R.1    Snowden, R.T.2    Cohen, G.M.3
  • 21
    • 0036401477 scopus 로고    scopus 로고
    • Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase
    • Watanabe N, Iwamoto T, Dickinson DA, Iles KE, Forman HJ. Activation of the mitochondrial caspase cascade in the absence of protein synthesis does not require c-Jun N-terminal kinase. Arch Biochem Biophys 2002; 405: 231-40.
    • (2002) Arch Biochem Biophys , vol.405 , pp. 231-240
    • Watanabe, N.1    Iwamoto, T.2    Dickinson, D.A.3    Iles, K.E.4    Forman, H.J.5
  • 22
    • 0032788432 scopus 로고    scopus 로고
    • Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells
    • Beidler DR, Ahuja D, Wicha MS, Toogood PL. Inhibition of protein synthesis by didemnin B is not sufficient to induce apoptosis in human mammary carcinoma (MCF7) cells. Biochem Pharmacol 1999; 58: 1067-74.
    • (1999) Biochem Pharmacol , vol.58 , pp. 1067-1074
    • Beidler, D.R.1    Ahuja, D.2    Wicha, M.S.3    Toogood, P.L.4
  • 23
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays. J Immunol Methods 1983; 65: 55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 24
    • 0032870081 scopus 로고    scopus 로고
    • Cytochemical methods for the detection of apoptosis
    • Willingham MC. Cytochemical methods for the detection of apoptosis. J Histochem Cytochem 1999; 47: 1101-9.
    • (1999) J Histochem Cytochem , vol.47 , pp. 1101-1109
    • Willingham, M.C.1
  • 25
    • 0030057708 scopus 로고    scopus 로고
    • Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at the single organelle level
    • Cossarizza A, Ceccarelli D, Masini A. Functional heterogeneity of an isolated mitochondrial population revealed by cytofluorometric analysis at the single organelle level. Exp Cell Res 1996; 222: 84-94.
    • (1996) Exp Cell Res , vol.222 , pp. 84-94
    • Cossarizza, A.1    Ceccarelli, D.2    Masini, A.3
  • 26
    • 0025726216 scopus 로고
    • A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
    • Nicoletti I, Migliorati G, Pagliacci MC, Grignani F, Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J Immunol Methods 1991; 139: 271-9.
    • (1991) J Immunol Methods , vol.139 , pp. 271-279
    • Nicoletti, I.1    Migliorati, G.2    Pagliacci, M.C.3    Grignani, F.4    Riccardi, C.5
  • 27
    • 0023768475 scopus 로고
    • The current state of two-dimensional electrophoresis with immobilized pH gradients
    • Görg A, Postel W, Günther S. The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 1988; 9: 531-46.
    • (1988) Electrophoresis , vol.9 , pp. 531-546
    • Görg, A.1    Postel, W.2    Günther, S.3
  • 28
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli UK. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970; 227: 680-5.
    • (1970) Nature , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 29
    • 0037444512 scopus 로고    scopus 로고
    • Fast-response proteomics by accelerated in-gel digestion of proteins
    • Havlis J, Thomas H, Sebela M, Shevchenko A. Fast-response proteomics by accelerated in-gel digestion of proteins. Anal Chem 2003; 75: 1300-6.
    • (2003) Anal Chem , vol.75 , pp. 1300-1306
    • Havlis, J.1    Thomas, H.2    Sebela, M.3    Shevchenko, A.4
  • 30
    • 33750420503 scopus 로고    scopus 로고
    • Reduction of cytotoxicity of the alkaloid emetine through P-glycoprotein (MDR1/ABCB1) in human Caco-2 cells and leukemia cell lines
    • Möller M, Weiss J, Wink M. Reduction of cytotoxicity of the alkaloid emetine through P-glycoprotein (MDR1/ABCB1) in human Caco-2 cells and leukemia cell lines. Planta Med 2006; 72: 1121-6.
    • (2006) Planta Med , vol.72 , pp. 1121-1126
    • Möller, M.1    Weiss, J.2    Wink, M.3
  • 31
    • 0032575705 scopus 로고    scopus 로고
    • A matter of life and cell death
    • Evan G, Littlewood T. A matter of life and cell death. Science 1998; 281: 1317-22.
    • (1998) Science , vol.281 , pp. 1317-1322
    • Evan, G.1    Littlewood, T.2
  • 33
    • 0035854661 scopus 로고    scopus 로고
    • Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis
    • Thiede B, Dimmler C, Siejak F, Rudel T. Predominant identification of RNA-binding proteins in Fas-induced apoptosis by proteome analysis. J Biol Chem 2001; 276: 26044-50.
    • (2001) J Biol Chem , vol.276 , pp. 26044-26050
    • Thiede, B.1    Dimmler, C.2    Siejak, F.3    Rudel, T.4
  • 34
    • 0032561365 scopus 로고    scopus 로고
    • Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3
    • Brockstedt E, Rickers A, Kostka S, Laubersheimer A, Doerken B, Wittmann-Liebold B et al. Identification of apoptosis-associated proteins in a human Burkitt lymphoma cell line. Cleavage of heterogeneous nuclear ribonucleoprotein A1 by caspase 3. J Biol Chem 1998; 273: 28057-64.
    • (1998) J Biol Chem , vol.273 , pp. 28057-28064
    • Brockstedt, E.1    Rickers, A.2    Kostka, S.3    Laubersheimer, A.4    Doerken, B.5    Wittmann-Liebold, B.6
  • 36
    • 0034855450 scopus 로고    scopus 로고
    • Proteomic analysis of apoptosis initiation induced by all-trans retinoic acid in human acute promyelocytic leukemia cells
    • Wan J, Wang J, Cheng H, Yu Y, Xing G, Qiu Z et al. Proteomic analysis of apoptosis initiation induced by all-trans retinoic acid in human acute promyelocytic leukemia cells. Electrophoresis 2001; 22: 3026-37.
    • (2001) Electrophoresis , vol.22 , pp. 3026-3037
    • Wan, J.1    Wang, J.2    Cheng, H.3    Yu, Y.4    Xing, G.5    Qiu, Z.6
  • 37
    • 0242413674 scopus 로고    scopus 로고
    • Proteome analysis of Vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations
    • Verrills NM, Walsh BJ, Cobon GS, Hains PG, Kavallaris M. Proteome analysis of Vinca alkaloid response and resistance in acute lymphoblastic leukemia reveals novel cytoskeletal alterations. J Biol Chem 2003; 278: 45082-93.
    • (2003) J Biol Chem , vol.278 , pp. 45082-45093
    • Verrills, N.M.1    Walsh, B.J.2    Cobon, G.S.3    Hains, P.G.4    Kavallaris, M.5
  • 38
    • 0035819883 scopus 로고    scopus 로고
    • Two-dimensional gel electrophoresis: A powerful method to elucidate cellular responses to toxic compounds
    • Möller A, Soldan M, Völker U, Maser E. Two-dimensional gel electrophoresis: a powerful method to elucidate cellular responses to toxic compounds. Toxicology 2001; 160: 129-38.
    • (2001) Toxicology , vol.160 , pp. 129-138
    • Möller, A.1    Soldan, M.2    Völker, U.3    Maser, E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.