First characterization of heterogeneous resistance to imipenem in invasive nontypeable Haemophilus influenzae isolates

Antimicrobial Agents and Chemotherapy

Volumn 51, Issue 9, 2007, Pages 3155-3161

  Cerquetti, Marina ^a   Giufrè, Maria ^a   Cardines, Rita ^a   Mastrantonio, Paola ^a  

^a ISTITUTO SUPERIORE DI SANITÀ   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; CEFOTAXIME; CHLORAMPHENICOL; IMIPENEM; PENICILLIN BINDING PROTEIN; PENICILLIN BINDING PROTEIN 3; PROTEIN ACRAB; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL GENE; BACTERIAL GENETICS; BACTERIAL GROWTH; BACTERIAL STRAIN; BACTERIUM ISOLATE; FTSI GENE; HAEMOPHILUS INFLUENZAE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; QUANTITATIVE ANALYSIS;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; DNA, BACTERIAL; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; GENES, BACTERIAL; HAEMOPHILUS INFECTIONS; HAEMOPHILUS INFLUENZAE; IMIPENEM; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PENICILLIN-BINDING PROTEINS; TRANSFORMATION, BACTERIAL;

EID: 35949002763     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.00335-07     Document Type: Article

References (32)

1. Brown, S. D., and M. M. Traczewski. 2005. Comparative in vitro antimicrobial activity of a new carbapenem, doripenem: tentative disc diffusion criteria and quality control. J. Antimicrob. Chemother. 55:944-949.
2. Burns, J. L., and A. L. Smith. 1987. A major outer-membrane protein functions as a porin in Haemophilus influenzae. J. Clin. Microbiol. 133:1273-1277.
3. Campos, J., M. Hernando, F. Roman, M. Perez-Vazquez, B. Aracil, J. Oteo, E. Labaro, F. de Abajo, and the Group of Invasive Haemophilus Infections of the Autonomous Community of Madrid, Spain. 2004. Analysis of invasive Haemophilus influenzae infections after extensive vaccination against H. influenzae type b. J. Clin. Microbiol. 42:524-529.
4. Cerquetti, M., R. Cardines, M. Giufrè, and P. Mastrantonio. 2004. Antimicrobial susceptibility of Haemophilus influenzae strains isolated from invasive disease in Italy. J. Antimicrob. Chemother. 54:1139-1143.
5. Cerquetti, M., M. L. Ciofi degli Atti, G. Renna, A. E. Tozzi, M. L. Garlaschi, P. Mastrantonio, and the Hi Study Group. 2000. Characterization of non-type b Haemophilus influenzae strains isolated from patients with invasive disease. J. Clin. Microbiol. 38:4649-4652.
6. Chesnel, L., R. Carapito, J. Croizé, O. Dideberg, T. Fernet, and A. Zapun. 2005. Identical penicillin-binding domains in penicillin-binding proteins of Streptococcus pneumoniae clinical isolates with different levels of β-lactam resistance. Antimicrob. Agents Chemother. 49:2895-2902.
7. Clairoux, N., M. Picard, A. Brochu, N. Rousseau, P. Gourde, D. Beauchamp, T. R. Parr, M. G. Bergeron, and F. Malouin. 1992. Molecular basis of the non-β-lactamase-mediated resistance to β-lactam antibiotics in strains of Haemophilus influenzae isolated in Canada. Antimicrob. Agents Chemother. 36:1504-1513.
8. Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing; fifteenth informational supplement. M100-s15, vol. 25, no. 1. Clinical and Laboratory Standards Institute, Wayne, PA.
9. Dabernat, H., C. Delmas, M. Seguy, R. Pelissier, G. Faucon, S. Bennamani, and C. Pasquier. 2002. Diversity of β-lactam resistance-conferring amino acid substitutions in penicillin-binding protein 3 of Haemophilus influenzae. Antimicrob. Agents Chemother. 46:2208-2218.
10. Dean, C. R., S. Narayan, D. M. Daigle, J. L. Dzink-Fox, X. Puyang, K. R. Bracken, K. E. Dean, B. Weidmann, Z. Yuan, R. Jain, and N. S. Ryder. 2005. Role of the AcrAB-TolC efflux pump in determining susceptibility of Haemophilus influenzae to the novel peptide deformylase inhibitor LBM415. Antimicrob. Agents Chemother. 49:3129-3135.
11. Erwin, A. I., K. L. Nelson, T. Mhlanga-Mutangadura, P. J. Bonthuis, J. L. Geelhood, G. Morlin, W. C. T. Unrath, J. Campos, D. W. Crook, M. M. Farley, F. W. Henderson, R. F. Jacobs, K. Mülhemann, S. W. Satola, L. van Alphen, M. Golomb, and A. L. Smith. 2005. Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae. Infect. Immun. 73:5853-5863.
12. Fernandez-Cuenca, F., L. Martinez-Martinez, M. C. Conejo, J. A. Ayala, E. J. Perea, and A. Pascual. 2003. Relationship between beta-lactamase production, outer membrane protein and penicillin-binding protein profiles on the activity of carbapenems against clinical isolates of Acinetobacter baumannii. J. Antimicrob. Chemother. 51:565-574.
13. Hiramatsu, K. 1995. Molecular evolution of MRSA. Microbiol. Immunol. 8:531-543.
14. Kaczmarek, F. S., T. D. Gootz, F. Dib-Hajj, W. Shang, S. Hallowell, and M. Cronan. 2004. Genetic and molecular characterization of β-lactamase-negative ampicillin-resistant Haemophilus influenzae with unusually high resistance to ampicillin. Antimicrob. Agents Chemother. 48:1630-1639.
15. Kim, I. S., C. S. Ki, S. Kim, W. S. Oh, K. R. Peck, J. H. Song, K. Lee, and N. Y. Lee. 2007. Diversity of ampicillin resistance genes and antimicrobial susceptibility patterns in Haemophilus influenzae strains isolated in Korea. Antimicrob. Agents Chemother. 51:453-460.
16. Limansky, A. S., M. A. Mussi, and A. M. Viale. 2002. Loss of a 29-kilodalton outer membrane protein in Acinetobacter baumannii is associated with imipenem resistance. J. Clin. Microbiol. 40:4776-4778.
17. Liu, C., and H. F. Chambers. 2003. Staphylococcus aureus with heterogeneous resistance to vancomycin: epidemiology, clinical significance, and critical assessment of diagnostic methods. Antimicrob. Agents Chemother. 47: 3040-3045.
18. Meats, M. E., J. Feil, S. Stringer, A. J. C. Cody, R. Goldstein, J. S. Kroll, T. Popovic, and B. G. Spratt. 2003. Characterization of encapsulated and noncapsulated Haemophilus influenzae and determination of phylogenetic relationships by multilocus sequence typing. J. Clin. Microbiol. 41:1623-1636.
19. Moreira, M. A. S., J. A Oliveira, L. M. Teixeria, and C. A. Moraes. 2005. Detection of a chloramphenicol efflux system in Escherichia coli isolated from poultry carcass. Vet. Microbiol. 109:75-81.
20. Nordmann, P., and L. Poire. 2002. Emerging carbapenemases in gram-negative aerobes. Clin. Microbiol. Infect. 8:321-331.
21. Osaki, Y., Y. Sanbongi, M. Ishigawa, H. Kataoka, T. Suzuki, K. Maeda, and T. Ida. 2005. Genetic approach to study the relationship between penicillin-binding protein 3 mutations and Haemophilus influenzae β-lactam resistance by using site-directed mutagenesis and gene recombinants. Antimicrob. Agents Chemother. 49:2834-2839.
22. Peric, M., B. Bozdogan, M. R. Jacobs, and P. C. Appelbaum. 2003. Effects of an efflux mechanism and ribosomal mutations on macrolide susceptibility of Haemophilus influenzae clinical isolates. Antimicrob. Agents Chemother. 47:1017-1022.
23. Rohrer, S., H. Maki, and B. Berger-Bächi. 2003. What makes resistance to methicillin heterogeneous? J. Med. Microbiol. 52:605-607.
24. Sanbongi, Y., T. Suzuki, Y. Osaki, N. Senju, T. Ida, and K. Ubukata. 2006. Molecular evolution of β-lactam-resistant Haemophilus influenzae: 9-year surveillance of penicillin-binding protein 3 mutations in isolates from Japan. Antimicrob. Agents Chemother. 50:2487-2492.
25. Sanchez, L., W. Pan, M. Viňas, and H. Nikaido. 1997. The acrAB homolog of Haemophilus influenzae codes for a functional multidrug efflux pump. J. Bacteriol. 179:6855-6857.
26. Sarangi, J., K. Cartwright, J. Stuart, S. Brookes, R. Morris, and M. Slack. 2000. Invasive Haemophilus influenzae disease in adults. Epidemiol. Infect. 124:441-447.
27. Shuichi, M., T. Fujikawa, K. Kanazawa, and K. Yamaguchi. 2001. In vitro and in vivo activities of meropenem and comparable antimicrobial agents against Haemophilus influenzae, including β-lactamase-negative ampicillin-resistant strains. J. Antimicrob. Chemother. 48:723-726.
28. Sieradzki, K., P. Villari, and A. Tomasz. 1998. Decreased susceptibilities to teicoplanin and vancomycin among coagulase-negative methicillin-resistant clinical isolates of staphylococci. Antimicrob. Agents Chemother. 42:100-107.
29. Straker, K., M. Wootton, A. M. Simm, P. M. Bennett, A. P. MacGowan, and T. R. Walsh. 2003. Cefuroxime resistance in non-β-lactamase Haemophilus influenzae is linked to mutations in ftsI. J. Antimicrob. Chemother. 51:523-530.
30. Trepod, C. M., and J. E. Mott. 2004. Identification of the Haemophilus influenzae tolC gene by susceptibility profiles of insertionally inactivated efflux pump mutants. Antimicrob. Agents Chemother. 48:1416-1418.
31. Ubukata, K., Y. Shibasaki, K. Yamamoto, N. Chiba, K. Hasegawa, Y. Takeuchi, K. Sunakawa, M. Inoue, and M. Konno. 2001. Association of amino acid substitutions in penicillin-binding protein 3 with β-lactam resistance in β-lactamase-negative ampicillin-resistant Haemophilus influenzae. Antimicrob. Agents Chemother. 45:1693-1699.
32. Vicente, M., M. J. Gomez, and J. A. Ayala. 1998. Regulation of transcription of cell division genes in the Escherichia coli dcw cluster. Cell. Mol. Life Sci. 54:317-324.